Epigenetic modification of ferroptosis by non-coding RNAs in cancer drug resistance

• Published in: Molecular cancer Vol. 23; no. 1; pp. 177 - 22
• Main Authors: Wang, Hongquan, Fleishman, Joshua S., Cheng, Sihang, Wang, Weixue, Wu, Fan, Wang, Yumin, Wang, Yu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.08.2024; BioMed Central; BMC
• Subjects: Animals; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Cancer; Cell death; Chemotherapy; Development and progression; Drug resistance; Drug Resistance, Neoplasm - genetics; Drug therapy; Epigenesis, Genetic; Epigenetic inheritance; Ferroptosis; Ferroptosis - drug effects; Ferroptosis - genetics; Gene Expression Regulation, Neoplastic - drug effects; Humans; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - metabolism; Neoplasms - pathology; Non-coding RNAs; Review; RNA, Untranslated - genetics; Non-coding RNAs; Ferroptosis; Drug resistance; Cancer

The development of drug resistance remains a major challenge in cancer treatment. Ferroptosis, a unique type of regulated cell death, plays a pivotal role in inhibiting tumour growth, presenting new opportunities in treating chemotherapeutic resistance. Accumulating studies indicate that epigenetic...