A mushroom-derived amino acid, ergothioneine, is a potential inhibitor of inflammation-related DNA halogenation - Asahi, Takashi; Wu, Xiaohong; Shimoda, Hiroshi; Hisaka, Shinsuke; Harada, Etsuko; Kanno, Tomomi; Nakamura, Yoshimasa; Kato, Yoji; Osawa, Toshihiko (Bioscience, biotechnology, and biochemistry, 2016)
Keywords: Agaricales - chemistry; amino acids; Animals; anti-inflammatory agent; anti-inflammatory agents; Anti-Inflammatory Agents - isolation & purification; Anti-Inflammatory Agents - pharmacology; ascorbic acid; Ascorbic Acid - pharmacology; biotechnology; Bromates - antagonists & inhibitors; Bromates - metabolism; Coprinus comatus; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - antagonists & inhibitors; Deoxyguanosine - biosynthesis; disease progression; DNA; DNA - antagonists & inhibitors; DNA - metabolism; ergothioneine; Ergothioneine - isolation & purification; Ergothioneine - pharmacology; glutathione; Glutathione - pharmacology; Halogenation - drug effects; hypobromous acid; Hypochlorous Acid - antagonists & inhibitors; Hypochlorous Acid - metabolism; Inflammation - drug therapy; Inflammation - etiology; Inflammation - metabolism; Inflammation - pathology; Male; Mice; Mice, Hairless; mushroom; mushrooms; myeloperoxidase; Peroxidase - antagonists & inhibitors; Peroxidase - metabolism; Ultraviolet Rays - adverse effects; ergothioneine; hypobromous acid; myeloperoxidase; mushroom; anti-inflammatory agent