The Akt Pathway Is Involved in Rapid Ischemic Tolerance in Focal Ischemia in Rats

• Published in: Translational stroke research Vol. 1; no. 3; pp. 202 - 209
• Main Authors: Gao, Xuwen, Zhang, Hanfeng, Steinberg, Gary, Zhao, Heng
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 01.09.2010; Springer Nature B.V
• Subjects: Antibodies; Apoptosis; Biomedical and Life Sciences; Biomedicine; Brain; Cardiology; Hypothermia; Ischemia; Kinases; Laboratory animals; Lasers; Membranes; Neurology; Neurosciences; Neurosurgery; Original Article; Phosphorylation; Proteins; Vascular Surgery; Veins & arteries; Ischemic tolerance; Focal ischemia; Neuroprotection; Cerebral ischemia; Rapid preconditioning; Akt

Although the protective mechanisms of delayed ischemic preconditioning have received extensive studies, few have addressed the mechanisms associated with rapid ischemic preconditioning. We investigated whether ischemic tolerance induced by rapid preconditioning is regulated by the Akt survival signa...