Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study

• Published in: Translational psychiatry Vol. 8; no. 1; pp. 130 - 10
• Main Authors: Pan, Jun-Xi, Xia, Jin-Jun, Deng, Feng-Li, Liang, Wei-Wei, Wu, Jing, Yin, Bang-Min, Dong, Mei-Xue, Chen, Jian-Jun, Ye, Fei, Wang, Hai-Yang, Zheng, Peng, Xie, Peng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 10.07.2018; Nature Publishing Group
• Subjects: 631/378/340; 692/53/2421; 692/699/476/1414; 82/16; 82/58; Behavioral Sciences; Biological Psychology; Biomarkers; Medicine; Medicine & Public Health; Mental depression; Metabolites; Neurosciences; Neurotransmitters; Pharmacotherapy; Plasma; Psychiatry

Major depressive disorder (MDD) is a debilitating psychiatric illness. However, there is currently no objective laboratory-based diagnostic tests for this disorder. Although, perturbations in multiple neurotransmitter systems have been implicated in MDD, the biochemical changes underlying the disord...