High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities - Hart, Traver; Chandrashekhar, Megha; Aregger, Michael; Steinhart, Zachary; Brown, Kevin R.; MacLeod, Graham; Mis, Monika; Zimmermann, Michal; Fradet-Turcotte, Amelie; Sun, Song; Mero, Patricia; Dirks, Peter; et al. (Cell, 2015)
Keywords: analytical methods; Bayes Theorem; Bayesian theory; Cell Line, Tumor; CRISPR-Cas Systems; Gene Knockout Techniques; Gene Library; Genes, Essential; human cell lines; Humans; Mutation; oncogenes; receptor protein-tyrosine kinase; therapeutics