Biomimetic proteolipid vesicles for targeting inflamed tissues

• Published in: Nature materials Vol. 15; no. 9; pp. 1037 - 1046
• Main Authors: Molinaro, R., Corbo, C., Martinez, J. O., Taraballi, F., Evangelopoulos, M., Minardi, S., Yazdi, I. K., Zhao, P., De Rosa, E., Sherman, M. B., De Vita, A., Toledano Furman, N. E., Wang, X., Parodi, A., Tasciotti, E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2016; Nature Publishing Group
• Subjects: 639/925/352/152; 692/308/575; Biomaterials; Biomimetics; Carriers; Condensed Matter Physics; Dexamethasone; Drug delivery systems; Formulations; Leukocytes; Lipids; Materials Science; Mathematical models; Nanoparticles; Nanotechnology; Optical and Electronic Materials; Physicochemical properties; Proteins; Strategy; Vesicles; Walls

A multitude of micro- and nanoparticles have been developed to improve the delivery of systemically administered pharmaceuticals, which are subject to a number of biological barriers that limit their optimal biodistribution. Bioinspired drug-delivery carriers formulated by bottom-up or top-down stra...