The genetic risk factors for cerebral venous thrombosis: a case-control study in a Chinese national comprehensive hospital

• Published in: Thrombosis journal Vol. 22; no. 1; pp. 50 - 11
• Main Authors: Wang, Shaoying, Yao, Ming, Yang, Xinzhuang, Zhu, Yicheng, Peng, Bin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.06.2024; BioMed Central; BMC
• Subjects: Brain damage; Care and treatment; Cerebral venous thrombosis; Complications and side effects; Genetic aspects; Health aspects; Hereditary thrombophilia; Intracranial hypertension; MAP kinase signaling pathway; Oral contraceptives; Risk factor; Risk factors; Venous thrombosis; Whole exome sequencing; China; Hereditary thrombophilia; Whole exome sequencing; MAP kinase signaling pathway; Cerebral venous thrombosis; Risk factor

About 13-25% of cerebral venous thrombosis (CVT) cases lack clear etiology, which may be associated with underlying genetic factors. This study aims to investigate genetic factors in CVT patients using whole exome sequencing (WES). Thirty-eight CVT patients hospitalized underwent WES. 977 subjects w...