Nutrition and Training Influences on the Regulation of Mitochondrial Adenosine Diphosphate Sensitivity and Bioenergetics

• Published in: Sports medicine (Auckland) Vol. 47; no. Suppl 1; pp. 13 - 21
• Main Author: Holloway, Graham P.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.03.2017; Springer Nature B.V
• Subjects: Adaptation; Adenosine; Adenosine Diphosphate; Athletes; Bioenergetics; Biosynthesis; Efficiency; Electron transport; Electron transport chain; Energy Metabolism; Exercise; Exercise - physiology; Fitness training programs; Humans; Influence; Medicine; Medicine & Public Health; Metabolism; Mitochondria; Mitochondria - metabolism; Mitochondria, Muscle; Muscle, Skeletal - metabolism; Musculoskeletal system; Nitrates; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical fitness; Physiology; Reactive oxygen species; Respiration; Review; Review Article; Skeletal muscle; Sodium; Sodium nitrate; Species; Sports Medicine; Transcription; Transcription Factors - metabolism; Mitochondrial Reactive Oxygen Species; Exercise Performance; Mitochondrial Biogenesis; Exercise Training; Mitochondrial Content

Since the seminal finding almost 50 years ago that exercise training increases mitochondrial content in skeletal muscle, a considerable amount of research has been dedicated to elucidate the mechanisms inducing mitochondrial biogenesis. The discovery of peroxisome proliferator-activated receptor γ c...