Intravenous leiomyomatosis: an unusual intermediate between benign and malignant uterine smooth muscle tumors

• Published in: Modern pathology Vol. 29; no. 5; pp. 500 - 510
• Main Authors: Ordulu, Zehra, Nucci, Marisa R, Dal Cin, Paola, Hollowell, Monica L, Otis, Christopher N, Hornick, Jason L, Park, Peter J, Kim, Tae-Min, Quade, Bradley J, Morton, Cynthia C
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.05.2016; Elsevier Limited
• Subjects: 13/106; 13/51; 14/32; 38/61; 631/208/1405; 631/337/103; 631/67/1517; 692/420/755; 692/699/2732; Cytogenetic Analysis; Female; Fibroids; Gene Expression Profiling; Humans; Hybridization; Informatics; Laboratory Medicine; Leiomyoma - genetics; Leiomyoma - pathology; Leiomyomatosis - genetics; Leiomyomatosis - pathology; Medicine; Medicine & Public Health; original-article; Pathogenesis; Pathology; Smooth muscle; Smooth Muscle Tumor - genetics; Smooth Muscle Tumor - pathology; Transcriptome; Tumors; Uterine Neoplasms - genetics; Uterine Neoplasms - pathology; Uterus; Vascular Neoplasms - genetics; Vascular Neoplasms - pathology; Women; United States > US

Intravenous leiomyomatosis is an unusual smooth muscle neoplasm with quasi-malignant intravascular growth but a histologically banal appearance. Herein, we report expression and molecular cytogenetic analyses of a series of 12 intravenous leiomyomatosis cases to better understand the pathogenesis of...