The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic

• Published in: NPJ microgravity Vol. 3; no. 1; pp. 15 - 9
• Main Authors: Tirumalai, Madhan R., Karouia, Fathi, Tran, Quyen, Stepanov, Victor G., Bruce, Rebekah J., Ott, C. Mark, Pierson, Duane L., Fox, George E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.05.2017; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326; 704/158/855; Adaptation; Antibiotic resistance; Applied Microbiology; Bacteria; Biomedical and Life Sciences; Biotechnology; Cell culture; Classical and Continuum Physics; Deoxyribonucleic acid; DNA; E coli; Escherichia coli; Fluid flow; Immunology; Life Sciences; Mechanical stimuli; Microgravity; Mutation; Nucleotide sequence; Space Exploration and Astronautics; Space flight; Space Sciences (including Extraterrestrial Physics

Microorganisms impact spaceflight in a variety of ways. They play a positive role in biological systems, such as waste water treatment but can be problematic through buildups of biofilms that can affect advanced life support. Of special concern is the possibility that during extended missions, the m...