Ferroptosis: past, present and future

• Published in: Cell death & disease Vol. 11; no. 2; p. 88
• Main Authors: Li, Jie, Cao, Feng, Yin, He-liang, Huang, Zi-jian, Lin, Zhi-tao, Mao, Ning, Sun, Bei, Wang, Gang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.02.2020; Springer Nature B.V
• Subjects: 631/80/82; 631/80/86; Acute Kidney Injury - drug therapy; Acute Kidney Injury - pathology; Antibodies; Antioxidants; Antioxidants - metabolism; Apoptosis; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cell death; Cell Death - drug effects; Cell Death - physiology; Ferroptosis; Ferroptosis - drug effects; Ferroptosis - physiology; Glutathione; Glutathione peroxidase; Hematological diseases; Immunology; Iron; Iron - metabolism; Ischemia; Life Sciences; Lipid Metabolism; Lipid Peroxidation; Molecular modelling; Neoplasms - drug therapy; Neoplasms - pathology; Nervous system; Nervous system diseases; Nervous System Diseases - drug therapy; Nervous System Diseases - pathology; Reactive oxygen species; Reperfusion; Reperfusion Injury - drug therapy; Reperfusion Injury - pathology; Review; Review Article; Tumors

Ferroptosis is a new type of cell death that was discovered in recent years and is usually accompanied by a large amount of iron accumulation and lipid peroxidation during the cell death process; the occurrence of ferroptosis is iron-dependent. Ferroptosis-inducing factors can directly or indirectly...