Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease and mortality in the general population

• Published in: Diabetologia Vol. 62; no. 2; pp. 269 - 280
• Main Authors: van Waateringe, Robert P., Fokkens, Bernardina T., Slagter, Sandra N., van der Klauw, Melanie M., van Vliet-Ostaptchouk, Jana V., Graaff, Reindert, Paterson, Andrew D., Smit, Andries J., Lutgers, Helen L., Wolffenbuttel, Bruce H. R.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2019; Springer Nature B.V
• Subjects: Adult; Aged; Aging; Blood Glucose; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - diagnostic imaging; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - mortality; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - diagnostic imaging; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - mortality; Female; Human Physiology; Humans; Incidence; Internal Medicine; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic syndrome; Middle Aged; Mortality; Myocardial infarction; Optical Imaging - methods; Population studies; Prospective Studies; Risk Factors; Skin - diagnostic imaging; Skin diseases; Stroke; Surgery; Transient ischemic attack; Skin autofluorescence; Diabetes; Cardiovascular; Ageing; Mortality; Prediction

Aims/hypothesis Earlier studies have shown that skin autofluorescence measured with an AGE reader estimates the accumulation of AGEs in the skin, which increases with ageing and is associated with the metabolic syndrome and type 2 diabetes. In the present study, we examined whether the measurement o...