Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation - Abdella, Ryan; Aggarwal, Megha; Okura, Takashi; Lamb, Robert A.; He, Yuan (Proceedings of the National Academy of Sciences - PNAS, 2020)
Keywords: Animal diseases; Animal health; Antiviral agents; BASIC BIOLOGICAL SCIENCES; Biological Sciences; Catalytic Domain; Cryo-EM; Cryoelectron Microscopy; Crystallography; Crystallography, X-Ray; DNA-directed RNA polymerase; Domains; Enzymatic activity; Genome, Viral; Genomes; Methyltransferase; Methyltransferases - chemistry; Methyltransferases - genetics; Methyltransferases - metabolism; Models, Molecular; Nucleoproteins - chemistry; Nucleotides; Oligomerization; Parainfluenza; Parainfluenza Virus 5 - chemistry; Paramyxovirinae - enzymology; Paramyxovirinae - genetics; paramyxovirus; Phosphoproteins - chemistry; polymerase; Protein Binding; Protein Conformation; Protein Domains; Protein structure; replication; RNA polymerase; RNA viruses; RNA-directed RNA polymerase; Transcription; Viral Proteins - chemistry; Viral Proteins - metabolism; Viruses; X-ray crystallography; replication; transcription; Cryo-EM; polymerase; paramyxovirus