A Physiologically-Based Pharmacokinetic Model to Describe Ciprofloxacin Pharmacokinetics Over the Entire Span of Life - Schlender, Jan-Frederik; Teutonico, Donato; Coboeken, Katrin; Schnizler, Katrin; Eissing, Thomas; Willmann, Stefan; Jaehde, Ulrich; Stass, Heino (Clinical pharmacokinetics, 2018)
Keywords: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Adults; Age; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacokinetics; Antibiotics; Area Under Curve; Child; Child, Preschool; Ciprofloxacin - administration & dosage; Ciprofloxacin - pharmacokinetics; Clinical trials; Computer Simulation; Cystic fibrosis; Drug dosages; Drug therapy; Female; Geriatrics; Humans; Infant; Infant, Newborn; Internal Medicine; Male; Medicine; Medicine & Public Health; Metabolism; Metabolites; Middle Aged; Models, Biological; Original; Original Research Article; Patients; Pediatrics; Pharmacokinetics; Pharmacology/Toxicology; Pharmacotherapy; Physiology; Reproducibility of Results; Studies; Young Adult