Root remodeling mechanisms and salt tolerance trade-offs: The roles of HKT1, TMAC2, and TIP2;2 in Arabidopsis

• Published in: PLoS genetics Vol. 21; no. 6; p. e1011713
• Main Authors: Alshareef, Nouf O., Melino, Vanessa J., Saber, Noha, De Rosa, Annamaria, Rey, Elodie, Wang, Jian You, AlBabili, Salim, Byrt, Caitlin, Tester, Mark A., Julkowska, Magdalena M.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.06.2025; Public Library of Science (PLoS)
• Subjects: Abscisic Acid - metabolism; Aquaporins - genetics; Aquaporins - metabolism; Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Basic-Leucine Zipper Transcription Factors - genetics; Basic-Leucine Zipper Transcription Factors - metabolism; Cation Transport Proteins - genetics; Cation Transport Proteins - metabolism; Environmental aspects; Gene Expression Regulation, Plant; Genetic aspects; Plant genetics; Plant Roots - genetics; Plant Roots - growth & development; Plant Roots - metabolism; Salt stress (Botany); Salt Stress - genetics; Salt Tolerance - genetics; Signal Transduction; Sodium - metabolism; Symporters - genetics; Symporters - metabolism; Transcription Factors - genetics; United States

Plant responses to salt stress involve regulatory networks integrating ion transport, hormonal signaling, and root system architecture remodeling. A key adaptive mechanism is the regulation of sodium (Na⁺) transport by Class 1 HKT1 transporters, which compertamentalize Na⁺ in non-photosynthetic tiss...