Drug-Induced Conditioned Place Preference and Its Practical Use in Substance Use Disorder Research

• Published in: Frontiers in behavioral neuroscience Vol. 14; p. 582147
• Main Authors: McKendrick, Greer, Graziane, Nicholas M.
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 29.09.2020; Frontiers Media S.A
• Subjects: addiction-like behavior; Animal behavior; Behavioral Neuroscience; conditioned place preference; CPP; Drug abuse; drug reward; Drug use; drugs of abuse; Emotional behavior; Motivation; Narcotics; Nervous system; Neurosciences; Place preference conditioning; Reinforcement; Self-administration; Substance use disorder

The conditioned place preference (CPP) paradigm is a well-established model utilized to study the role of context associations in reward-related behaviors, including both natural rewards and drugs of abuse. In this review, we discuss the basic history, various uses, and considerations that are tied...