Multiomics resolution of molecular events during a day in the life of Chlamydomonas

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 116; no. 6; pp. 2374 - 2383
• Main Authors: Strenkert, Daniela, Schmollinger, Stefan, Gallaher, Sean D., Salomé, Patrice A., Purvine, Samuel O., Nicora, Carrie D., Mettler-Altmann, Tabea, Soubeyrand, Eric, Weber, Andreas P. M., Lipton, Mary S., Basset, Gilles J., Merchant, Sabeeha S.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 05.02.2019; National Academy of Sciences, Washington, DC (United States)
• Series: PNAS Plus
• Subjects: Aeration; Algae; BASIC BIOLOGICAL SCIENCES; Biological Sciences; Cell Division; Changing environments; Chlamydomonas - genetics; Chlamydomonas - metabolism; Chlamydomonas reinhardtii; chloroplast; DNA Replication; Fermentation; Ferredoxin; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes; Genomes; Genomics - methods; Glycolysis; histone expression; Light intensity; Luminous intensity; Metabolism; Metabolites; Metabolome; Metabolomics - methods; NAD - metabolism; Night; Oxidation-Reduction; photo-bioreactor; Photosynthesis - genetics; Pigments; Plant communities; Plant populations; PNAS Plus; Proteins; Proteome; Proteomes; Proteomics - methods; Signal Transduction; systems biology; Transcriptome; systems biology; cell division; photobioreactor; chloroplast; histone expression

The unicellular green alga Chlamydomonas reinhardtii displays metabolic flexibility in response to a changing environment. We analyzed expression patterns of its three genomes in cells grown under light–dark cycles. Nearly 85% of transcribed genes show differential expression, with different sets of...