Roles of circular RNAs in immune regulation and autoimmune diseases

• Published in: Cell death & disease Vol. 10; no. 7; pp. 503 - 13
• Main Authors: Zhou, Zheng, Sun, Bao, Huang, Shiqiong, Zhao, Lingling
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.06.2019; Springer Nature B.V
• Subjects: 631/250/38; 692/420/2780; Animals; Antibodies; Autoimmune diseases; Autoimmune Diseases - genetics; Autoimmune Diseases - immunology; Autoimmune Diseases - metabolism; Autoimmunity - genetics; Autoimmunity - immunology; Autoimmunity - physiology; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cholangitis; Evolutionary conservation; Humans; Immune system; Immunology; Immunoregulation; Life Sciences; Liver Cirrhosis, Biliary - genetics; Liver Cirrhosis, Biliary - immunology; Liver Cirrhosis, Biliary - metabolism; Lupus Erythematosus, Systemic - genetics; Lupus Erythematosus, Systemic - immunology; Lupus Erythematosus, Systemic - metabolism; Multiple sclerosis; Multiple Sclerosis - genetics; Multiple Sclerosis - immunology; Multiple Sclerosis - metabolism; Psoriasis; Psoriasis - genetics; Psoriasis - immunology; Psoriasis - metabolism; Review; Review Article; Rheumatoid arthritis; RNA, Circular - genetics; RNA, Circular - physiology; Systemic lupus erythematosus

Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs (ncRNAs), have a high stability and often present tissue-specific expression and evolutionary conservation. Emerging evidence has suggested that circRNAs play an essential role in complex human pathologies. Notably,...