Chromosome substitution strain assessment of a Huntington’s disease modifier locus - Ramos, Eliana Marisa; Kovalenko, Marina; Guide, Jolene R.; St. Claire, Jason; Gillis, Tammy; Mysore, Jayalakshmi S.; Sequeiros, Jorge; Wheeler, Vanessa C.; Alonso, Isabel; MacDonald, Marcy E. (Mammalian genome, 2015)
Keywords: Alleles; Animal Genetics and Genomics; Animals; Biomedical and Life Sciences; Body Weight; Cell Biology; chromosome substitution; Chromosomes, Human; Chromosomes, Mammalian; Crosses, Genetic; crossing; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics; Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism; Female; Gene Knock-In Techniques; genes; Genetic Variation; Genomic Instability; Genotype; Human Genetics; Humans; Huntingtin Protein; Huntington Disease - genetics; Life Sciences; liver; loci; Male; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins - genetics; neurodegenerative diseases; Neurons - metabolism; Phenotype; progeny; Quantitative Trait Loci; Trinucleotide Repeats; weight gain; Mutant Huntingtin; Somatic Instability; Intranuclear Inclusion; Repeat Instability; Chromosome Substitution Strain