Transcranial Focused Ultrasound Neuromodulation: A Review of the Excitatory and Inhibitory Effects on Brain Activity in Human and Animals

• Published in: Frontiers in human neuroscience Vol. 15; p. 749162
• Main Authors: Zhang, Tingting, Pan, Na, Wang, Yuping, Liu, Chunyan, Hu, Shimin
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 28.09.2021; Frontiers Media S.A
• Subjects: Ablation; animal; Animals; Brain research; Cavitation; Cell membranes; human; Ion channels; Mental disorders; Neurodegenerative diseases; Neuromodulation; Neuroscience; non-invasive brain stimulation; Peripheral nerves; Reflexes; Thalamus; Thermal injury; transcranial focused ultrasound; Ultrasonic imaging; Ultrasound

Non-invasive neuromodulation technology is important for the treatment of brain diseases. The effects of focused ultrasound on neuronal activity have been investigated since the 1920s. Low intensity transcranial focused ultrasound (tFUS) can exert non-destructive mechanical pressure effects on cellu...