NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer - Yu, Min; Ni, Mengdong; Xu, Fei; Liu, Chaohua; Chen, Lihua; Li, Jiana; Xia, Siyu; Diao, Yixin; Chen, Jiaxin; Zhu, Jun; Wu, Xiaohua; Tang, Min; et al. (Molecular cancer, 2024)
Keywords: 3D bioprinted patient-derived organoid; 5-Methylcytosine - analogs & derivatives; 5-Methylcytosine - metabolism; Analysis; Animals; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cell Line, Tumor; Cervical cancer; DNA; Drug resistance; Ethylenediaminetetraacetic acid; Female; Gene Expression Regulation, Neoplastic; Genes; Humans; Intracellular Signaling Peptides and Proteins - genetics; Intracellular Signaling Peptides and Proteins - metabolism; Liquid chromatography; m5C modification; Mass spectrometry; Messenger RNA; Methyltransferases - genetics; Methyltransferases - metabolism; Mice; NSUN6; Prognosis; Radiation; Radiation Tolerance - genetics; Radioresistance; RNA sequencing; RNA, Messenger - genetics; RNA, Messenger - metabolism; Uterine Cervical Neoplasms - genetics; Uterine Cervical Neoplasms - metabolism; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - radiotherapy; Xenograft Model Antitumor Assays; China; Radioresistance; 3D bioprinted patient-derived organoid; NSUN6; Cervical cancer; m5C modification