Repeatability of Radiomic Features in Non-Small-Cell Lung Cancer [18F]FDG-PET/CT Studies: Impact of Reconstruction and Delineation

• Published in: Molecular imaging and biology Vol. 18; no. 5; pp. 788 - 795
• Main Authors: van Velden, Floris H. P., Kramer, Gerbrand M., Frings, Virginie, Nissen, Ida A., Mulder, Emma R., de Langen, Adrianus J., Hoekstra, Otto S., Smit, Egbert F., Boellaard, Ronald
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2016; Springer Nature B.V
• Subjects: Aged; Carcinoma, Non-Small-Cell Lung - diagnostic imaging; Carcinoma, Non-Small-Cell Lung - pathology; Demography; Female; Fluorodeoxyglucose F18 - chemistry; Humans; Image Processing, Computer-Assisted; Imaging; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Male; Medicine; Medicine & Public Health; Middle Aged; Positron Emission Tomography Computed Tomography; Radiology; Reproducibility of Results; Research Article; Repeatability; Tracer uptake heterogeneity; Non-small-cell lung cancer (NSCLC); PET/CT; Radiomics

Purpose To assess (1) the repeatability and (2) the impact of reconstruction methods and delineation on the repeatability of 105 radiomic features in non-small-cell lung cancer (NSCLC) 2-deoxy-2-[ 18 F]fluoro-D-glucose ([ 18 F]FDG) positron emission tomorgraphy/computed tomography (PET/CT) studies....