Three-dimensional conformal radiotherapy (3D-CRT) versus intensity modulated radiation therapy (IMRT) in squamous cell carcinoma of the head and neck: A randomized controlled trial

• Published in: Radiotherapy and oncology Vol. 104; no. 3; pp. 343 - 348
• Main Authors: Gupta, Tejpal, Agarwal, JaiPrakash, Jain, Sandeep, Phurailatpam, Reena, Kannan, Sadhana, Ghosh-Laskar, Sarbani, Murthy, Vedang, Budrukkar, Ashwini, Dinshaw, Ketayun, Prabhash, Kumar, Chaturvedi, Pankaj, D’Cruz, Anil
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.09.2012
• Subjects: 3D-CRT; Adult; Aged; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - radiotherapy; Female; Head and Neck Neoplasms - mortality; Head and Neck Neoplasms - radiotherapy; Head-neck cancer; Hematology, Oncology and Palliative Medicine; Humans; IMRT; Male; Middle Aged; Radiotherapy, Conformal - adverse effects; Radiotherapy, Conformal - methods; Radiotherapy, Intensity-Modulated - adverse effects; Radiotherapy, Intensity-Modulated - methods; Squamous Cell Carcinoma of Head and Neck; Subcutaneous fibrosis; Xerostomia; Subcutaneous fibrosis; Head-neck cancer; 3D-CRT; IMRT; Xerostomia

To compare three-dimensional conformal radiotherapy (3D-CRT) with intensity modulated radiation therapy (IMRT) in curative-intent irradiation of head-neck squamous cell carcinoma (HNSCC). Previously untreated patients with biopsy-proven squamous carcinoma of oropharynx, larynx, or hypopharynx (T1-3,...