Comparison of sevelamer and calcium carbonate on endothelial function and inflammation in patients on peritoneal dialysis

• Published in: Journal of renal care Vol. 39; no. 2; p. 82
• Main Authors: Chennasamudram, Sudha P, Noor, Tanjila, Vasylyeva, Tetyana L
• Format: Journal Article
• Language: English
• Published: United States 01.06.2013
• Subjects: Adult; Aged; Biomarkers; Calcium - blood; Calcium Carbonate - therapeutic use; Chelating Agents - therapeutic use; Cross-Over Studies; Cytokines - blood; Diabetes Mellitus, Type 2 - complications; Endothelial Cells - physiology; Female; Humans; Hyperphosphatemia - etiology; Hyperphosphatemia - therapy; Inflammation - physiopathology; Lipids - blood; Male; Middle Aged; Peritoneal Dialysis; Phosphates - blood; Polyamines - therapeutic use; Serum Albumin; Sevelamer; Treatment Outcome

Hyperphosphataemia is a known independent risk factor for cardiovascular mortality. The objective of the study was to compare the effects of two phosphate binders, sevelamer carbonate and calcium carbonate on endothelial function (EF) and inflammation in patients on peritoneal dialysis (PD) with Typ...