Tracking the Continuous Evolutionary Processes of an Endogenous Retrovirus of the Domestic Cat: ERV-DC

• Published in: Viruses Vol. 10; no. 4; p. 179
• Main Authors: Kawasaki, Junna, Nishigaki, Kazuo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.04.2018; MDPI
• Subjects: Binding sites; Cats; Cloning; domestic cat; Domestication; endogenous retrovirus; ERV-DC; Evolution; Experiments; Feline leukemia; feline leukemia virus; feline leukemia virus subgroup D; Felis silvestris catus; Genes; Genomes; Genotype & phenotype; Genotypes; Infections; Laboratory animals; Leukemia; Phylogeny; Proviruses; RD-114; Recombination; Refrex-1; retroviral restriction factor; Review; Viral infections; Virulence factors; Viruses; endogenous retrovirus; retroviral restriction factor; RD-114; domestic cat; ERV-DC; Felis silvestris catus; feline leukemia virus; feline leukemia virus subgroup D; Refrex-1

An endogenous retrovirus (ERV) is a remnant of an ancient retroviral infection in the host genome. Although most ERVs have lost their viral productivity, a few ERVs retain their replication capacity. In addition, partially inactivated ERVs can present a potential risk to the host via their encoded v...