Development of psychophysiological motoric reactivity is influenced by peripubertal pharmacological inhibition of gonadotropin releasing hormone action – Results of an ovine model

• Published in: Psychoneuroendocrinology Vol. 37; no. 11; pp. 1876 - 1884
• Main Authors: Evans, Neil P, Robinson, Jane E, Erhard, Hans W, Ropstad, Erik, Fleming, Lynne M, Haraldsen, Ira Ronit Hebold
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.11.2012; Elsevier
• Subjects: Animal biology; Animals; Behavioral psychophysiology; Biological and medical sciences; Cortisol; Emotional reactivity; Emotions - drug effects; Endocrinology & Metabolism; Female; Fundamental and applied biological sciences. Psychology; GnRH; GnRH agonist; Gonadotropin-Releasing Hormone - antagonists & inhibitors; Gonadotropin-Releasing Hormone - physiology; Goserelin - pharmacology; Hormones and behavior; Hydrocortisone - blood; Life Sciences; Litter Size; Male; Motor Activity - drug effects; Motor Activity - physiology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychophysiological motoric reactivity; Puberty; Sex Factors; Sexual Maturation - drug effects; Sheep; Sheep - growth & development; Sheep - physiology; Stress; Vocalization, Animal - drug effects; Puberty; GnRH agonist; Emotional reactivity; Sheep; Cortisol; Psychophysiological motoric reactivity; GnRH; Stress; Affect affectivity; Agonist; Gonadotropin RH; Hydrocortisone; Glucocorticoid; Development; Inhibition; Hormone releasing factor; Ungulata; Psychophysiology; Corticosteroid; Steroid hormone; Antiinflammatory agent; Emotion emotionality; Hypothalamic hormone; Vertebrata; Mammalia; Reactivity; Animal; Adrenal hormone; Models; Artiodactyla; stress; cortisol; psychophysiological motoric reactivity; puberty; emotional reactivity; sheep

Summary This study reports the effects of peripubertal GnRH receptor inactivation on development of psychophysiological motoric reactivity (PMR; sometimes also called emotional reactivity), plasma cortisol concentrations and the relationship between plasma cortisol and PMR in male and female sheep....