Chlorhexidine - Pharmacology and Clinical Applications

• Published in: Anaesthesia and intensive care Vol. 36; no. 4; pp. 502 - 512
• Main Authors: Lim, K. -S., Kam, P.C.A.
• Format: Journal Article
• Language: English
• Published: Edgecliff Anaesthesia and Intensive Care 01.07.2008; Sage Publications Ltd. (UK); Sage Publications Ltd
• Subjects: Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anti-Infective Agents, Local - adverse effects; Anti-Infective Agents, Local - pharmacology; Bacteremia - microbiology; Bacteremia - prevention & control; Biological and medical sciences; Catheterization - adverse effects; Catheterization - methods; Chlorhexidine; Chlorhexidine - adverse effects; Chlorhexidine - pharmacology; Cross Infection - prevention & control; Dermatomycoses - prevention & control; Diagnosis; Dosage and administration; Drug Hypersensitivity - etiology; Drug therapy; Equipment Contamination - prevention & control; Hand Disinfection - methods; Humans; Iodine - pharmacology; Medical sciences; Oral Hygiene - methods; Pharmacokinetics; Sepsis; Treatment Outcome; United States; Immunopathology; Allergy; Biguanides; Antiseptic; pharmacology; Clinical pharmacology; adverse effects; Anesthesia; clinical uses; Guanidines; Chlorhexidine; Disinfecting agent

chlorhexidine is a widely used skin antisepsis preparation and is an ingredient in toothpaste and mouthwash. It is an especially effective antiseptic when combined with alcohol. Its antimicrobial effects persist because it is binds strongly to proteins in the skin and mucosa, making it an effective...