Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020

• Published in: Euro surveillance : bulletin européen sur les maladies transmissibles Vol. 25; no. 16; p. 1
• Main Authors: Perera, Ranawaka APM, Mok, Chris KP, Tsang, Owen TY, Lv, Huibin, Ko, Ronald LW, Wu, Nicholas C, Yuan, Meng, Leung, Wai Shing, Chan, Jacky MC, Chik, Thomas SH, Choi, Chris YC, Leung, Kathy, Chan, Kin Ho, Chan, Karl CK, Li, Ka-Chi, Wu, Joseph T, Wilson, Ian A, Monto, Arnold S, Poon, Leo LM, Peiris, Malik
• Format: Journal Article
• Language: English
• Published: Sweden Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS) 23.04.2020; European Centre for Disease Prevention and Control (ECDC)
• Subjects: Adolescent; Adult; Aged; Animals; Betacoronavirus - immunology; Betacoronavirus - isolation & purification; Bioassays; Chlorocebus aethiops; Clinical Laboratory Techniques; Coronavirus Infections - diagnosis; COVID-19; COVID-19 Testing; Enzyme-Linked Immunosorbent Assay; Epidemiology; Female; Humans; Immunoglobulins; Male; Middle Aged; Neutralization Tests; Pandemics; Pneumonia, Viral - diagnosis; Proteins; Public health; Real-Time Polymerase Chain Reaction; SARS-CoV-2; Seroepidemiologic Studies; Serologic Tests - methods; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - analysis; Spike Glycoprotein, Coronavirus - immunology; Vero Cells; Young Adult; receptor binding domain; SARS-CoV-2; COVD19; neutralization; serology; ELISA
• ISSN: 1560-7917; 1025-496X; 1560-7917
• DOI: 10.2807/1560-7917.ES.2020.25.16.2000421

BackgroundThe ongoing coronavirus disease (COVID-19) pandemic has major impacts on health systems, the economy and society. Assessing infection attack rates in the population is critical for estimating disease severity and herd immunity which is needed to calibrate public health interventions. We ha...