CircBIRC6 affects prostate cancer progression by regulating miR-574-5p and DNAJB1

• Published in: Cancer biology & therapy Vol. 25; no. 1; p. 2399363
• Main Authors: Zhao, Bin, Yang, Jinye, Ran, Fengming, Shi, Yuanlong, Yang, Libo, Duan, Yuanpeng, Shi, Zhiyu, Li, Xin, Zhang, Jianpeng, Li, Zhiyao, Wang, Jiansong
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 31.12.2024; Taylor & Francis Group
• Subjects: Animals; autophagy; Autophagy - genetics; Cell Line, Tumor; Cell Movement - genetics; Cell Proliferation; circBIRC6; Disease Progression; DNAJB1; Gene Expression Regulation, Neoplastic; HSP40 Heat-Shock Proteins - genetics; HSP40 Heat-Shock Proteins - metabolism; Humans; Male; Mice; MicroRNAs - genetics; MicroRNAs - metabolism; miRNA-574-5p; Prostate cancer; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Research Paper; RNA, Circular - genetics; RNA, Circular - metabolism; DNAJB1; autophagy; circBIRC6; Prostate cancer; miRNA-574-5p

Prostate cancer (PCa) is among the three main types of cancer. Although prostate-specific antigen (PSA) is routinely tested, it has disadvantages, such as poor prognostic ability. Therefore, finding more PCa markers and therapeutic targets remains a subject of study. CircRNAs have been found to have...