The role of axon guidance molecules in the pathogenesis of epilepsy

• Published in: Neural regeneration research Vol. 20; no. 5; pp. 1244 - 1257
• Main Authors: Liu, Zheng, Pan, Chunhua, Huang, Hao
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt. Ltd 01.05.2025; Department of Neurology,Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou Province,China; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: axon guidance; drug-resistant epilepsy; Epilepsy; nerve regeneration; nervous system diseases; Neural networks; neural pathways; neuroinflammatory diseases; neuronal plasticity; neurons; Review; Synapses; synaptic remodeling; drug-resistant epilepsy; epilepsy; neural pathways; neuronal plasticity; nervous system diseases; neuroinflammatory diseases; synaptic remodeling; nerve regeneration; axon guidance; neurons

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence...