Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea

Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also po...

Full description

Saved in:
Bibliographic Details
Published inScience China. Life sciences Vol. 60; no. 4; pp. 370 - 385
Main Authors Peng, Nan, Han, Wenyuan, Li, Yingjun, Liang, Yunxiang, She, Qunxin
Format Journal Article
LanguageEnglish
Published Beijing Science China Press 01.04.2017
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats
CRISPR
DNA fingerprints
Gene Silencing
Genes, Archaeal
Genetic engineering
Genetic Markers
Genetic Vectors
Life Sciences
Microorganisms
Review
Sulfolobus - genetics
shuttle vector
gene knockout
genetic manipulation
selection and counter-selection
CRISPR-based gene editing
Sulfolobus
Online AccessGet full text

Cover

Abstract Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.
AbstractList Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.
Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.
Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.
Author Nan Peng Wenyuan Han Yingjun Li Yunxiang Liang Qunxin She
AuthorAffiliation State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China Archaeal Centre, Department of Biology, University of Copenhagen, Ole Maaloes Vej 5, Copenhagen DK-2200, Denmark
Author_xml – sequence: 1
  givenname: Nan
  surname: Peng
  fullname: Peng, Nan
  organization: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University
– sequence: 2
  givenname: Wenyuan
  surname: Han
  fullname: Han, Wenyuan
  organization: Archaeal Centre, Department of Biology, University of Copenhagen
– sequence: 3
  givenname: Yingjun
  surname: Li
  fullname: Li, Yingjun
  organization: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Archaeal Centre, Department of Biology, University of Copenhagen
– sequence: 4
  givenname: Yunxiang
  surname: Liang
  fullname: Liang, Yunxiang
  organization: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University
– sequence: 5
  givenname: Qunxin
  surname: She
  fullname: She, Qunxin
  email: qunxin@bio.ku.dk
  organization: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Archaeal Centre, Department of Biology, University of Copenhagen
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28251462$$D View this record in MEDLINE/PubMed
BookMark eNp9kU1vFSEUhompsbX2B7gxE924cJSPYYClabSaNHFh94TLHObSMHALM4ld-s9lnFtjuigLIOR5ziHnfYlOYoqA0GuCPxKMxadCSEdFi0nfYsZ5K5-hMyJ71RIp1Um996JrBcP8FF2UcovrYgxTIV6gUyopJ11Pz9DvK4gwe9vMYPcxhTR6KI1LuYFfc4YJwn0z7yFP6bD3oXKTtzmlPJroy1Sa5JqfS3BV3C3lw4o2KVZn3MqasPrZ2NnsAqyvy1_HZogm270B8wo9dyYUuDie5-jm65eby2_t9Y-r75efr1vLGZ9b2Q2ytwbLzjqH5aCsxIZIBT2AcoJwyjrLuBkMAw5yMKpjg6M9x8btFGXn6P1W9pDT3QJl1pMvFkIwEdJSNJGCCUqUIBV99wi9TUuO9XOVUkr0dVOVenOklt0Egz5kP5l8rx9mWwGxAXVgpWRw2vrZzD7FOhAfNMF6DVJvQeoapF6D1LKa5JH5UPwph25OqWwcIf_36Sekt8dG-xTHu-r969QLiplSHWZ_ADulvQw
CitedBy_id crossref_primary_10_1016_j_ijbiomac_2021_10_143
crossref_primary_10_1038_s41467_018_07379_4
crossref_primary_10_3390_biom13010114
crossref_primary_10_1080_15476286_2018_1460993
crossref_primary_10_3390_ijms23158515
crossref_primary_10_1042_ETLS20180023
crossref_primary_10_1128_JB_00580_17
crossref_primary_10_1093_nar_gky844
crossref_primary_10_1002_mlf2_12107
crossref_primary_10_1093_nar_gkae096
crossref_primary_10_1093_nar_gky487
crossref_primary_10_1111_1751_7915_13613
crossref_primary_10_1111_mmi_13973
crossref_primary_10_3389_fbioe_2023_1160012
crossref_primary_10_1093_nar_gkx791
crossref_primary_10_3390_genes9030128
crossref_primary_10_1038_s41467_019_12244_z
crossref_primary_10_1264_jsme2_ME19055
crossref_primary_10_3390_ijms25063137
crossref_primary_10_1016_j_jprot_2022_104681
crossref_primary_10_1371_journal_pone_0185791
crossref_primary_10_1111_1462_2920_15116
crossref_primary_10_1186_s13568_022_01447_1
crossref_primary_10_3389_fmicb_2020_01585
crossref_primary_10_1038_s41467_024_47697_4
crossref_primary_10_1016_j_biotechadv_2019_107433
crossref_primary_10_1093_nar_gkad006
crossref_primary_10_1128_jvi_01438_22
crossref_primary_10_3389_fmicb_2017_02474
crossref_primary_10_1016_j_celrep_2020_108133
crossref_primary_10_3389_fbioe_2022_920639
crossref_primary_10_3389_fmicb_2024_1443342
crossref_primary_10_3390_ijms21113935
crossref_primary_10_1128_AEM_02167_17
crossref_primary_10_1016_j_molcel_2020_07_008
crossref_primary_10_1093_femsml_uqab007
crossref_primary_10_1007_s11427_022_2412_3
crossref_primary_10_1080_15476286_2019_1642725
crossref_primary_10_1038_s41396_021_00984_0
crossref_primary_10_1093_femsre_fuy012
crossref_primary_10_1128_JB_00747_18
crossref_primary_10_3390_ijms18071340
Cites_doi 10.1099/mic.0.051862-0
10.1073/pnas.0801980105
10.1186/s12867-015-0030-z
10.1002/mbo3.198
10.1128/JB.01692-06
10.1128/MMBR.00042-14
10.1038/nature10886
10.1007/s007920050083
10.1074/jbc.M605549200
10.1073/pnas.89.16.7645
10.1016/j.jgg.2011.05.001
10.1093/nar/gkr1111
10.1016/S0966-842X(98)01281-5
10.1128/AEM.71.7.3889-3899.2005
10.1046/j.1365-2958.1999.01573.x
10.1093/nar/gkl615
10.1128/JB.183.9.2943-2946.2001
10.1074/jbc.M111.238485
10.1042/BST0390099
10.1128/JB.00558-06
10.1093/nar/gku215
10.1038/nature12352
10.1007/BF00446886
10.1006/plas.1996.0016
10.1093/nar/gkt767
10.1016/j.plasmid.2006.02.002
10.1016/S0923-2508(03)00074-3
10.1111/j.1365-2958.2011.07586.x
10.3390/life5010506
10.1111/mmi.12152
10.1128/AEM.00855-12
10.1126/science.aad5147
10.1128/JB.00042-07
10.3389/fmicb.2012.00214
10.4014/jmb.1407.07043
10.1099/mic.0.28861-0
10.1128/JB.187.14.4992-4999.2005
10.1038/nrmicro1852
10.1073/pnas.1513740113
10.3389/fmicb.2015.00023
10.1146/annurev.micro.57.030502.090709
10.1042/BST0370042
10.1128/AEM.01608-13
10.1371/journal.pbio.1001265
10.1046/j.1365-2958.2003.03509.x
10.1016/j.jgg.2011.05.003
10.1007/s00792-010-0338-z
10.1007/s00792-016-0807-0
10.1007/BF00408082
10.1006/jmbi.2000.4160
10.1128/jb.177.15.4417-4426.1995
10.1128/AEM.01951-09
10.1007/s11427-012-4325-8
10.1128/JB.182.9.2574-2581.2000
10.1016/j.jmb.2007.12.019
10.1080/106351501750435040
10.1007/s00792-010-0325-4
10.1111/j.1574-6976.1996.tb00229.x
10.1002/mbo3.128
10.1073/pnas.87.12.4576
10.1038/emboj.2010.101
10.1042/BST20120338
10.1007/s00203-008-0392-4
10.1111/j.1365-2958.2009.06908.x
10.1128/JB.185.1.210-220.2003
10.1093/nar/gkl623
10.3389/fmicb.2012.00195
10.1128/JB.01487-10
10.1042/BJ20101334
10.1073/pnas.74.11.5088
10.1016/S0723-2020(11)80333-4
10.1016/j.dnarep.2011.10.009
10.1128/JB.187.2.805-809.2005
10.4161/rna.24154
10.1007/s007920050032
10.4161/rna.23798
10.1016/j.mib.2005.10.001
10.1128/JB.00344-15
10.1261/rna.2679911
10.1016/S0300-9084(00)88892-6
10.1016/j.mib.2015.05.010
10.1016/S0378-1097(01)00504-3
10.1093/nar/gku1302
10.1128/JB.182.24.7014-7020.2000
10.1007/s007920050087
10.1099/mic.0.065854-0
10.1042/BST20120285
10.1042/BST0370092
10.1007/s00792-016-0867-1
10.1111/j.1365-2958.2010.07452.x
10.1007/s00792-016-0847-5
10.1093/nar/gkw286
10.1155/2004/151926
10.1128/JB.00061-06
10.1093/dnares/8.4.123
10.1007/s00792-014-0634-0
10.1128/JB.186.2.427-437.2004
10.1046/j.1365-2958.2001.02377.x
10.1016/j.jgg.2016.03.003
10.1128/JB.185.3.772-778.2003
10.1128/AEM.00455-16
10.1093/nar/gku1383
10.1073/pnas.141222098
10.1038/ismej.2012.20
10.1111/j.1574-6968.2001.tb10699.x
10.1093/nar/gkv1044
10.1007/s11427-012-4292-0
10.3390/life5010783
10.1093/nar/gkm449
10.1099/mic.0.042523-0
10.1016/j.virol.2007.01.035
10.1007/s007920050052
10.1016/j.jgg.2013.05.004
10.1111/j.1574-6976.2011.00265.x
10.1073/pnas.0808945106
10.1016/j.molcel.2006.07.019
10.1007/s00792-009-0254-2
10.1007/s00792-015-0734-5
10.1128/jb.178.11.3396-3398.1996
10.1155/2005/159218
10.1111/j.1365-2958.2007.05697.x
10.1128/AEM.72.1.102-111.2006
10.1128/AEM.06095-11
10.1007/s00253-011-3504-z
10.1128/JB.00638-07
10.1073/pnas.141113098
10.1128/JB.185.15.4657-4661.2003
10.1099/mic.0.058289-0
10.1128/JB.185.2.482-488.2003
10.1007/s00792-010-0304-9
10.1098/rsob.130010
10.1093/nar/gku161
10.1093/gbe/evu274
10.1016/j.celrep.2013.01.002
10.1155/2008/948014
10.1111/j.1574-6968.2008.01303.x
10.1038/nature14447
10.1046/j.1365-2958.2003.03444.x
10.1139/w05-147
10.1042/BST0390051
10.1002/j.1460-2075.1985.tb03702.x
10.1534/g3.116.032482
10.1093/genetics/152.4.1307
10.1093/genetics/152.4.1397
10.1128/JB.180.12.3237-3240.1998
ContentType Journal Article
Copyright Science in China Press and Springer-Verlag GmbH 2017
Science China Life Sciences is a copyright of Springer, 2017.
Copyright_xml – notice: Science in China Press and Springer-Verlag GmbH 2017
– notice: Science China Life Sciences is a copyright of Springer, 2017.
DBID 2RA
92L
CQIGP
~WA
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7QP
7TK
7U9
7X7
7XB
88A
88E
8AO
8FE
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
LK8
M0S
M1P
M7P
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
7X8
DOI 10.1007/s11427-016-0355-8
DatabaseName 维普_期刊
中文科技期刊数据库-CALIS站点
中文科技期刊数据库-7.0平台
中文科技期刊数据库- 镜像站点
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Calcium & Calcified Tissue Abstracts
Neurosciences Abstracts
Virology and AIDS Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Biology Database (Alumni Edition)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Database
ProQuest Central Database Suite (ProQuest)
Natural Science Collection
ProQuest One
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Collection (ProQuest)
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
ProQuest Health & Medical Collection
Medical Database
Biological Science Database
ProQuest Central Premium
ProQuest One Academic
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central China
ProQuest Biology Journals (Alumni Edition)
ProQuest Central
ProQuest One Applied & Life Sciences
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Health & Medical Research Collection
Biological Science Collection
AIDS and Cancer Research Abstracts
ProQuest Central (New)
ProQuest Medical Library (Alumni)
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList
ProQuest Central Student

MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
DocumentTitleAlternate Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea
EISSN 1869-1889
EndPage 385
ExternalDocumentID 28251462
10_1007_s11427_016_0355_8
672039940
Genre Journal Article
Review
GroupedDBID ---
-A0
-EM
-Y2
1N0
2B.
2C.
2RA
2VQ
3V.
4.4
406
40D
40G
53G
5VR
5VS
7X7
88A
88E
8AO
8FE
8FH
8FI
8FJ
8TC
92E
92I
92L
92Q
93N
AAAVM
AAFGU
AAHNG
AAIAL
AANXM
AANZL
AARHV
AATNV
AATVU
AAUYE
AAYFA
AAYQN
ABDZT
ABECU
ABFGW
ABFTV
ABJNI
ABJOX
ABKAS
ABKCH
ABMQK
ABQBU
ABSXP
ABTEG
ABTKH
ABTMW
ABUWG
ACAOD
ACBMV
ACBRV
ACBXY
ACBYP
ACGFS
ACHSB
ACIGE
ACIHN
ACIPQ
ACOKC
ACPRK
ACREN
ACTTH
ACVWB
ACWMK
ACZOJ
ADINQ
ADKNI
ADKPE
ADMDM
ADOXG
ADRFC
ADURQ
ADYFF
ADZKW
AEAQA
AEFTE
AEJRE
AEOHA
AEPYU
AESKC
AESTI
AEVLU
AEVTX
AEXYK
AFGXO
AFKRA
AFLOW
AFNRJ
AFQWF
AFUIB
AGDGC
AGGBP
AGJBK
AGMZJ
AGQMX
AHBYD
AHMBA
AHSBF
AHYZX
AIAKS
AILAN
AIMYW
AITGF
AJDOV
AJRNO
AJZVZ
AKQUC
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMTXH
AMXSW
AMYLF
AXYYD
BBNVY
BENPR
BGNMA
BHPHI
BPHCQ
BVXVI
C6C
CAG
CCEZO
CCPQU
CCVFK
COF
CQIGP
CSCUP
DIK
DNIVK
DPUIP
EBLON
EBS
EIOEI
EJD
EMOBN
F5P
FA0
FERAY
FIGPU
FINBP
FNLPD
FSGXE
FYUFA
GGCAI
GJIRD
GX1
H4N
HCIFZ
HG6
HMCUK
HZ~
IKXTQ
IWAJR
J-C
JZLTJ
KOV
KQ8
LK8
LLZTM
M0L
M1P
M4Y
M7P
NPVJJ
NQJWS
NU0
O9J
OK1
PQQKQ
PROAC
PSQYO
PT4
Q2X
RIG
RNS
ROL
RSV
SBL
SCL
SNE
SNPRN
SNX
SOHCF
SOJ
SPISZ
SRMVM
SSLCW
STPWE
SV3
TCJ
TGP
TR2
TSG
U2A
UG4
UKHRP
UOJIU
UTJUX
UZXMN
VFIZW
WK8
Z7U
Z87
ZMTXR
~WA
-SA
-S~
0R~
AACDK
AAJBT
AASML
AAXDM
AAYZH
ABAKF
ACDTI
ACPIV
AEFQL
AEMSY
AGQEE
AGRTI
AIGIU
ALIPV
BSONS
CAJEA
CJPJV
H13
Q--
SJYHP
U1G
U5K
AAYXX
ABBRH
ABDBE
ACMFV
AFDZB
AFOHR
AHPBZ
ATHPR
AYFIA
CITATION
PHGZM
PHGZT
CGR
CUY
CVF
ECM
EIF
NPM
7QP
7TK
7U9
7XB
8FK
ABRTQ
AZQEC
DWQXO
GNUQQ
H94
K9.
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQUKI
PRINS
7X8
ID FETCH-LOGICAL-c535t-84d86ca084cff08d9c80a189e6ee9f715234c35ada3e5e8da943df2650afb923
IEDL.DBID 7X7
ISSN 1674-7305
1869-1889
IngestDate Fri Jul 11 02:37:39 EDT 2025
Wed Aug 13 07:28:37 EDT 2025
Wed Feb 19 02:41:46 EST 2025
Tue Jul 01 03:56:16 EDT 2025
Thu Apr 24 23:05:56 EDT 2025
Fri Feb 21 02:34:56 EST 2025
Wed Feb 14 10:04:43 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords shuttle vector
gene knockout
genetic manipulation
selection and counter-selection
CRISPR-based gene editing
Sulfolobus
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c535t-84d86ca084cff08d9c80a189e6ee9f715234c35ada3e5e8da943df2650afb923
Notes 11-5841/Q
Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of the bacterial counterparts but sharing metabolic pathways with organisms of Bacteria, the sister prokaryotic phylum. Archaeal organisms also possess unique features as revealed by genomics and genome comparisons and by biochemical characterization of prominent enzymes. Nevertheless, diverse genetic tools are required for in vivo experiments to verify these interesting discoveries. Considerable efforts have been devoted to the development of genetic tools for archaea ever since their discovery, and great progress has been made in the creation of archaeal genetic tools in the past decade. Versatile genetic toolboxes are now available for several archaeal models, among which Sulfolobus microorganisms are the only genus representing Crenarchaeota because all the remaining genera are from Euryarchaeota. Nevertheless, genetic tools developed for Sulfolobus are probably the most versatile among all archaeal models, and these include viral and plasmid shuttle vectors, conventional and novel genetic manipulation methods, CRISPR-based gene deletion and mutagenesis, and gene silencing, among which CRISPR tools have been reported only for Sulfolobus thus far. In this review, we summarize recent developments in all these useful genetic tools and discuss their possible application to research into archaeal biology by means of Sulfolobus models.
plasmid promoter prokaryotic shuttle mutagenesis deletion silencing genomics diverse genera
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
PMID 28251462
PQID 1899768999
PQPubID 54335
PageCount 16
ParticipantIDs proquest_miscellaneous_1873721971
proquest_journals_1899768999
pubmed_primary_28251462
crossref_citationtrail_10_1007_s11427_016_0355_8
crossref_primary_10_1007_s11427_016_0355_8
springer_journals_10_1007_s11427_016_0355_8
chongqing_primary_672039940
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2017-04-01
PublicationDateYYYYMMDD 2017-04-01
PublicationDate_xml – month: 04
  year: 2017
  text: 2017-04-01
  day: 01
PublicationDecade 2010
PublicationPlace Beijing
PublicationPlace_xml – name: Beijing
– name: China
PublicationTitle Science China. Life sciences
PublicationTitleAbbrev Sci. China Life Sci
PublicationTitleAlternate Sci China Life Sci
PublicationYear 2017
Publisher Science China Press
Springer Nature B.V
Publisher_xml – name: Science China Press
– name: Springer Nature B.V
References Jaubert, Danioux, Oberto, Cortez, Bize, Krupovic, She, Forterre, Prangishvili, Sezonov (CR54) 2013; 3
Chen, Brügger, Skovgaard, Redder, She, Torarinsson, Greve, Awayez, Zibat, Klenk, Garrett (CR21) 2005; 187
Hansen, Dill, Grogan (CR46) 2005; 187
Villafane, Voskoboynik, Ruhl, Sannino, Maezato, Blum, Bini (CR123) 2011; 157
van Wolferen, Wagner, van der Does, Albers (CR122) 2016; 113
Peng, Li, Hallstrøm, Peng, Liang, She (CR86) 2013; 10
Wagner, van Wolferen, Wagner, Lassak, Meyer, Reimann, Albers (CR125) 2012; 3
Reilly, Grogan (CR93) 2001; 183
Stedman, She, Phan, Arnold, Holz, Garrett, Zillig (CR116) 2003; 154
Brock, Brock, Belly, Weiss (CR14) 1972; 84
Hong, Chu, Li, Ni, Sheng, Hou, She, Shen (CR49) 2012; 11
Peng, Deng, Mei, Jiang, Hu, Awayez, Liang, She (CR83) 2012; 78
Ruggero, Londei (CR99) 1996; 178
Prato, Cannio, Klenk, Contursi, Rossi, Bartolucci (CR90) 2006; 56
van Wolferen, Ma, Albers (CR121) 2015; 197
She, Phan, Garrett, Albers, Stedman, Zillig (CR109) 1998; 2
Contursi, Fusco, Cannio, She (CR26) 2014; 18
Li, Pan, Zhang, Ren, Feng, Peng, Chen, Liang, She (CR63) 2016; 44
Chaban, Ng, Jarrell (CR20) 2006; 52
Bitan-Banin, Ortenberg, Mevarech (CR12) 2003; 185
Liu, Han, Liu, Zhou, Xiang (CR68) 2011; 38
Zillig, Arnold, Holz, Prangishvili, Schweier, Stedman, She, Phan, Garrett, Kristjansson (CR145) 1998; 2
Deng, Garrett, Shah, Peng, She (CR30) 2013; 87
Huang, Liu, Liu, Ni, She, Shen (CR51) 2015; 16
Liu, Li, Wang, Ye, Li, Liang, She, Peng (CR69) 2015; 43
Schelert, Drozda, Dixit, Dillman, Blum (CR104) 2006; 188
Manica, Zebec, Teichmann, Schleper (CR74) 2011; 80
Delong, Pace (CR29) 2001; 50
Kletzin, Lieke, Urich, Charlebois, Sensen (CR60) 1999; 152
Redder, Garrett (CR92) 2006; 188
Spang, Saw, Jørgensen, Zaremba-Niedzwiedzka, Martijn, Lind, van Eijk, Schleper, Guy, Ettema (CR114) 2015; 521
She, Zhang, Deng, Peng, Chen, Liang (CR111) 2009; 37
Zebec, Manica, Zhang, White, Schleper (CR136) 2014; 42
Bell, Jackson (CR7) 1998; 6
Zillig, Kletzin, Schleper, Holz, Janekovic, Hain, Lanzendörfer, Kristjansson (CR146) 1993; 16
Jonuscheit, Martusewitsch, Stedman, Schleper (CR55) 2003; 48
Aucelli, Contursi, Girfoglio, Rossi, Cannio (CR6) 2006; 34
Cannio, Contursi, Rossi, Bartolucci (CR19) 1998; 180
Contursi, Cannio, Prato, She, Rossi, Bartolucci (CR22) 2007; 189
Aagaard, Leviev, Aravalli, Forterre, Prieur, Garrett (CR149) 1996; 18
Gudbergsdottir, Deng, Chen, Jensen, Jensen, She, Garrett (CR44) 2011; 79
Leigh, Albers, Atomi, Allers (CR61) 2011; 35
Zhang, Whitaker (CR143) 2012; 158
Albers, Jonuscheit, Dinkelaker, Urich, Kletzin, Tampé, Driessen, Schleper (CR3) 2006; 72
Cadillo-Quiroz, Didelot, Held, Herrera, Darling, Reno, Krause, Whitaker (CR17) 2012; 10
Zillig, Stetter, Wunderl, Schulz, Priess, Scholz (CR147) 1980; 125
Petitjean, Deschamps, López-García, Moreira (CR89) 2015; 7
Elkins, Podar, Graham, Makarova, Wolf, Randau, Hedlund, Brochier-Armanet, Kunin, Anderson, Lapidus, Goltsman, Barry, Koonin, Hugenholtz, Kyrpides, Wanner, Richardson, Keller, Stetter (CR34) 2008; 105
Hwang, Choi, Yoon, Cha (CR52) 2015; 25
Hjort, Bernander (CR48) 2001; 40
Zhang, She, Bi, Whitaker (CR141) 2016; 82
Mao, Grogan (CR75) 2012; 6
Zhang, Krause, Whitaker (CR140) 2013; 41
Song, Huang, Ni, Yu, Shen (CR112) 2016; 20
Stedman, She, Phan, Holz, Singh, Prangishvili, Garrett, Zillig (CR117) 2000; 182
Suzuki, Kurosawa (CR118) 2016; 20
Martusewitsch, Sensen, Schleper (CR77) 2000; 182
Zhang, Guo, Deng, Wu, Liang, Huang, She (CR139) 2010; 156
Berkner, Hinojosa, Prangishvili, Lipps (CR9) 2014; 3
Contursi, Cannio, She (CR23) 2010; 14
Sato, Fukui, Atomi, Imanaka (CR101) 2003; 185
Zheng, Huang, Zhang, Ni, She, Shen (CR144) 2012; 78
Kawarabayasi, Hino, Horikawa, Jin-no, Takahashi, Sekine, Baba, Ankai, Kosugi, Hosoyama, Fukui, Nagai, Nishijima, Otsuka, Nakazawa, Takamiya, Kato, Yoshizawa, Tanaka, Kudoh, Yamazaki, Kushida, Oguchi, Aoki, Masuda, Yanagii, Nishimura, Yamagishi, Oshima, Kikuchi (CR56) 2001; 8
Keeling, Klenk, Singh, Schenk, Sensen, Zillig, Doolittle (CR58) 1998; 2
Wang, Peng, Shah, Huang, She (CR126) 2015; 79
Lipps (CR66) 2009; 37
Manica, Schleper (CR72) 2013; 10
D’Auria, Moracci, Febbraio, Tanfani, Nucci, Rossi (CR27) 1998; 80
Garrett, Shah, Vestergaard, Deng, Gudbergsdottir, Kenchappa, Erdmann, She (CR38) 2011; 39
Hileman, Santangelo (CR47) 2012; 3
Brouns, Walther, Snijders, van de Werken, Willemen, Worm, de Vos, Andersson, Lundgren, Mazon, van den Heuvel, Nilsson, Salmon, de Vos, Wright, Bernander, van der Oost (CR15) 2006; 281
Garrett, Shah, Erdmann, Liu, Mousaei, León-Sobrino, Peng, Gudbergsdottir, Deng, Vestergaard, Peng, She (CR37) 2015; 5
Cammarano, Teichner, Londei, Acca, Nicolaus, Sanz, Amils (CR18) 1985; 4
Sato, Fukui, Atomi, Imanaka (CR102) 2005; 71
Lintner, Kerou, Brumfield, Graham, Liu, Naismith, Sdano, Peng, She, Copié, Young, White, Lawrence (CR65) 2011; 286
Ishino, Narumi (CR53) 2015; 25
Dai, Wang, Zhang, Li, Zhang, Mora-López, Jiang, Liu, Wang, Zhu, Hernández-Ascencio, Dong, Huang (CR28) 2016; 7
Stedman, Schleper, Rumpf, Zillig (CR115) 1999; 152
Maezato, Daugherty, Dana, Soo, Cooper, Tachdjian, Kelly, Blum (CR71) 2011; 17
Liu, She, Garrett (CR67) 2016; 44
Purschke, Schäfer (CR91) 2001; 200
Albers, Jarrell (CR2) 2015; 6
Guo, Brügger, Liu, Shah, Zheng, Zhu, Wang, Lillestøl, Chen, Frank, Prangishvili, Paulin, She, Huang, Garrett (CR45) 2011; 193
Zhang, Cooper, Krause, Whitaker (CR138) 2013; 79
Li, Guo, Deng, Feng, Ren, Chu, She, Huang (CR62) 2011; 38
Kelman, White (CR59) 2005; 8
Contursi, D'Ambrosio, Pirone, Pedone, Aucelli, She, De Simone, Bartolucci (CR24) 2011; 435
Yan, Huang, Ni, Shen (CR135) 2016; 20
Waege, Schmid, Thumann, Thomm, Hausner (CR124) 2010; 76
Manica, Zebec, Steinkellner, Schleper (CR73) 2013; 41
Xiang, Huang, Wang, Huang (CR134) 2015; 5
Arnold, She, Phan, Stedman, Prangishvili, Holz, Kristjansson, Garrett, Zillig (CR5) 1999; 34
Doré, Kilkenny, Jones, Oliver, Roe, Bell, Pearl (CR33) 2006; 34
Schleper, Holz, Janekovic, Murphy, Zillig (CR106) 1995; 177
Peng, Ao, Liang, She (CR82) 2011; 39
Szabó, Sani, Groeneveld, Zolghadr, Schelert, Albers, Blum, Boekema, Driessen (CR119) 2007; 189
Reno, Held, Fields, Burke, Whitaker (CR94) 2009; 106
Fukuda, Morimoto, Imanaka, Fujiwara (CR36) 2008; 287
Ma, Hong, Han, Sheng, Ni, Hou, Shen (CR70) 2011; 15
Berkner, Wlodkowski, Albers, Lipps (CR11) 2010; 14
Deng, Kenchappa, Peng, She, Garrett (CR31) 2012; 40
Brochier-Armanet, Boussau, Gribaldo, Forterre (CR13) 2008; 6
Brügger, Redder, She, Confalonieri, Zivanovic, Garrett (CR16) 2002; 206
Keeling, Klenk, Singh, Feeley, Schleper, Zillig, Doolittle, Sensen (CR57) 1996; 35
Song, Ni, Shen (CR113) 2016; 43
Greve, Jensen, Brügger, Zillig, Garrett (CR40) 2004; 1
Woese, Fox (CR130) 1977; 74
Worthington, Hoang, Perez-Pomares, Blum (CR133) 2003; 185
McCarthy, Gradnigo, Johnson, Payne, Lipzen, Martin, Schackwitz, Moriyama, Blum (CR79) 2015; 3
Zebec, Zink, Kerou, Schleper (CR137) 2016; 6
Huang, Li, Zeng, Song, Yan, Ni, She, Shen (CR50) 2015; 19
Roberts, Bell, White (CR97) 2003; 48
Rudolf, Makrantoni, Ingledew, Stark, White (CR98) 2006; 23
Matsumi, Manabe, Fukui, Atomi, Imanaka (CR78) 2007; 189
Peng, Feng, Feng, Liang, She (CR85) 2015; 43
Richards, Cubeddu, Roberts, Liu, White (CR95) 2008; 376
Contursi, Farina, Pirone, Fusco, Russo, Bartolucci, Fattorusso, Pedone (CR25) 2014; 42
Schelert, Rudrappa, Johnson, Blum (CR105) 2013; 159
She, Singh, Confalonieri, Zivanovic, Allard, Awayez, Chan-Weiher, Groth Clausen, Curtis, De Moors, Erauso, Fletcher, Gordon, Heikamp-de Jong, Jeffries, Kozera, Medina, Peng, Phan Thi-Ngoc, Redder, Schenk, Theriault, Tolstrup, Charlebois, Ford Doolittle, Duguet, Gaasterland, Garrett, Ragan, Sensen, Van der Oost (CR110) 2001; 98
Greve, Jensen, Phan, Brügger, Zillig, She, Garrett (CR41) 2005; 1
Deng, Zhu, Chen, Liang, She (CR32) 2009; 13
Zhang, Tian, Li, Ao, Dalgaard, Gökce, Liang, She (CR142) 2013; 41
Grabowski, Kelman (CR39) 2003; 57
Liang, Han, Huang, Li, Ni, She, Shen (CR64) 2013; 40
Berkner, Lipps (CR10) 2008; 190
Wong, Brown, Suo, Blum, Nohmi, Ling (CR132) 2010; 29
Wang, Duan, Zhu, Guo, Wang, Zhou, She, Huang (CR128) 2007; 363
She, Deng, Zhu, Chen, Dreibrøl, Awayez, Liang, Liu, Drake (CR108) 2008
Woese, Kandler, Wheelis (CR131) 1990; 87
Schleper, Kubo, Zillig (CR107) 1992; 89
Zolghadr, Weber, Szabó, Driessen, Albers (CR148) 2007; 64
Grogan (CR42) 2003; 185
Samson, Xu, Gadelha, Stone, Faqiri, Li, Qin, Pu, Liang, She, Bell (CR100) 2013; 3
Schelert, Dixit, Hoang, Simbahan, Drozda, Blum (CR103) 2004; 186
Martin, Yeats, Janekovic, Reiter, Aicher, Zillig (CR76) 1984; 3
Peng, Garrett, She (CR87) 2012; 55
Berkner, Grogan, Albers, Lipps (CR8) 2007; 35
Erauso, Stedman, van de Werken, Zillig, van der Oost (CR35) 2006; 152
Albers, Driessen (CR1) 2008; 2
Wang, Sheng, Han, Huang, Zhu, Ni, Li, Shen (CR127) 2012; 55
van Wolferen, Ajon, Driessen, Albers (CR120) 2013; 2
Wiedenheft, Sternberg, Doudna (CR129) 2012; 482
Aravalli, Garrett (CR4) 1997; 1
Grogan, Carver, Drake (CR43) 2001; 98
Mohanraju, Makarova, Zetsche, Zhang, Koonin, van der Oost (CR81) 2016; 353
Rinke, Schwientek, Sczyrba, Ivanova, Anderson, Cheng, Darling, Malfatti, Swan, Gies, Dodsworth, Hedlund, Tsiamis, Sievert, Liu, Eisen, Hallam, Kyrpides, Stepanauskas, Rubin, Hugenholtz, Woyke (CR96) 2013; 499
Peng, Xia, Chen, Liang, She (CR84) 2009; 74
Peng, Holz, Zillig, Garrett, She (CR88) 2000; 303
Mei, Peng, Zhao, Hu, Wang, Liang, She (CR80) 2012; 93
J. Schelert (355_CR104) 2006; 188
Z. Zebec (355_CR137) 2016; 6
M. Wolferen van (355_CR121) 2015; 197
P. Mohanraju (355_CR81) 2016; 353
X. Peng (355_CR88) 2000; 303
X. Song (355_CR113) 2016; 43
S.V. Albers (355_CR1) 2008; 2
Y. Mei (355_CR80) 2012; 93
E.F. Delong (355_CR29) 2001; 50
P.J. Keeling (355_CR57) 1996; 35
M. Wagner (355_CR125) 2012; 3
Z. Kelman (355_CR59) 2005; 8
A. Martin (355_CR76) 1984; 3
A. Kletzin (355_CR60) 1999; 152
W. Peng (355_CR85) 2015; 43
K.M. Stedman (355_CR116) 2003; 154
B. Greve (355_CR41) 2005; 1
P. Contursi (355_CR22) 2007; 189
H. Liu (355_CR68) 2011; 38
J. Schelert (355_CR105) 2013; 159
C. Schleper (355_CR107) 1992; 89
M. Jonuscheit (355_CR55) 2003; 48
I. Waege (355_CR124) 2010; 76
L. Wang (355_CR127) 2012; 55
P. Contursi (355_CR26) 2014; 18
P. Redder (355_CR92) 2006; 188
R.A. Garrett (355_CR37) 2015; 5
X. Li (355_CR62) 2011; 38
R. Cannio (355_CR19) 1998; 180
Q. She (355_CR108) 2008
W. Zillig (355_CR146) 1993; 16
D. Ruggero (355_CR99) 1996; 178
T. Liu (355_CR69) 2015; 43
J.E. Hansen (355_CR46) 2005; 187
J.A. Leigh (355_CR61) 2011; 35
P.J. Liang (355_CR64) 2013; 40
J.A. Roberts (355_CR97) 2003; 48
Q. Huang (355_CR50) 2015; 19
A. Manica (355_CR74) 2011; 80
Z. Szabó (355_CR119) 2007; 189
C. Zhang (355_CR138) 2013; 79
L. Guo (355_CR45) 2011; 193
X. Peng (355_CR87) 2012; 55
H.P. Arnold (355_CR5) 1999; 34
D. Mao (355_CR75) 2012; 6
Q. She (355_CR109) 1998; 2
D.W. Grogan (355_CR43) 2001; 98
K. Brügger (355_CR16) 2002; 206
S. McCarthy (355_CR79) 2015; 3
D.W. Grogan (355_CR42) 2003; 185
S. Suzuki (355_CR118) 2016; 20
G. Erauso (355_CR35) 2006; 152
W. Zillig (355_CR145) 1998; 2
T. Aucelli (355_CR6) 2006; 34
S. Gudbergsdottir (355_CR44) 2011; 79
Z. Zebec (355_CR136) 2014; 42
C. Schleper (355_CR106) 1995; 177
A. Villafane (355_CR123) 2011; 157
L. Deng (355_CR32) 2009; 13
Y. Li (355_CR63) 2016; 44
Q. Huang (355_CR51) 2015; 16
S.D. Bell (355_CR7) 1998; 6
G. Liu (355_CR67) 2016; 44
N.G. Lintner (355_CR65) 2011; 286
G. Lipps (355_CR66) 2009; 37
C. Brochier-Armanet (355_CR13) 2008; 6
R. Matsumi (355_CR78) 2007; 189
J.G. Elkins (355_CR34) 2008; 105
B. Chaban (355_CR20) 2006; 52
L. Deng (355_CR31) 2012; 40
W. Fukuda (355_CR36) 2008; 287
A. Spang (355_CR114) 2015; 521
X. Song (355_CR112) 2016; 20
X. Dai (355_CR28) 2016; 7
P.J. Keeling (355_CR58) 1998; 2
G. Bitan-Banin (355_CR12) 2003; 185
X. Ma (355_CR70) 2011; 15
N. Peng (355_CR82) 2011; 39
C. Zhang (355_CR141) 2016; 82
L. Chen (355_CR21) 2005; 187
J. Rudolf (355_CR98) 2006; 23
B. Wiedenheft (355_CR129) 2012; 482
R.Y. Samson (355_CR100) 2013; 3
Q. She (355_CR111) 2009; 37
X. Xiang (355_CR134) 2015; 5
S. Berkner (355_CR11) 2010; 14
H. Wang (355_CR126) 2015; 79
C.R. Woese (355_CR130) 1977; 74
J.D. Richards (355_CR95) 2008; 376
S. Hwang (355_CR52) 2015; 25
M. Wolferen van (355_CR120) 2013; 2
M.L. Reno (355_CR94) 2009; 106
T. Zheng (355_CR144) 2012; 78
P. Contursi (355_CR23) 2010; 14
S. Prato (355_CR90) 2006; 56
J. Schelert (355_CR103) 2004; 186
Y. Hong (355_CR49) 2012; 11
W. Peng (355_CR86) 2013; 10
P. Worthington (355_CR133) 2003; 185
N. Peng (355_CR84) 2009; 74
R.N. Aravalli (355_CR4) 1997; 1
S. Berkner (355_CR9) 2014; 3
Y. Wang (355_CR128) 2007; 363
C. Zhang (355_CR143) 2012; 158
N. Peng (355_CR83) 2012; 78
Y. Kawarabayasi (355_CR56) 2001; 8
S.J.J. Brouns (355_CR15) 2006; 281
W.G. Purschke (355_CR91) 2001; 200
C. Rinke (355_CR96) 2013; 499
T. Sato (355_CR101) 2003; 185
S. D’Auria (355_CR27) 1998; 80
S. Berkner (355_CR10) 2008; 190
M.S. Reilly (355_CR93) 2001; 183
B. Grabowski (355_CR39) 2003; 57
S.V. Albers (355_CR3) 2006; 72
A. Manica (355_CR72) 2013; 10
C. Zhang (355_CR140) 2013; 41
A. Manica (355_CR73) 2013; 41
Z. Yan (355_CR135) 2016; 20
C. Petitjean (355_CR89) 2015; 7
S.V. Albers (355_CR2) 2015; 6
S. Berkner (355_CR8) 2007; 35
L. Deng (355_CR30) 2013; 87
J.H.Y. Wong (355_CR132) 2010; 29
T.D. Brock (355_CR14) 1972; 84
Y. Maezato (355_CR71) 2011; 17
K.M. Stedman (355_CR115) 1999; 152
C.R. Woese (355_CR131) 1990; 87
Y. Ishino (355_CR53) 2015; 25
T. Sato (355_CR102) 2005; 71
C. Aagaard (355_CR149) 1996; 18
K.M. Stedman (355_CR117) 2000; 182
C. Zhang (355_CR139) 2010; 156
B. Greve (355_CR40) 2004; 1
M. Wolferen van (355_CR122) 2016; 113
Q. She (355_CR110) 2001; 98
H. Cadillo-Quiroz (355_CR17) 2012; 10
K. Hjort (355_CR48) 2001; 40
P. Contursi (355_CR25) 2014; 42
T.H. Hileman (355_CR47) 2012; 3
P. Contursi (355_CR24) 2011; 435
W. Zillig (355_CR147) 1980; 125
P. Cammarano (355_CR18) 1985; 4
E. Martusewitsch (355_CR77) 2000; 182
C. Zhang (355_CR142) 2013; 41
A.S. Doré (355_CR33) 2006; 34
B. Zolghadr (355_CR148) 2007; 64
R.A. Garrett (355_CR38) 2011; 39
C. Jaubert (355_CR54) 2013; 3
References_xml – volume: 157
  start-page: 2808
  year: 2011
  end-page: 2817
  ident: CR123
  article-title: CopR of represents a novel class of archaeal-specific copper-responsive activators of transcription
  publication-title: Microbiol
  doi: 10.1099/mic.0.051862-0
– volume: 105
  start-page: 8102
  year: 2008
  end-page: 8107
  ident: CR34
  article-title: A korarchaeal genome reveals insights into the evolution of the archaea
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0801980105
– volume: 16
  start-page: 2
  year: 2015
  ident: CR51
  article-title: Efficient 5′-3′ DNA end resection by HerA and NurA is essential for cell viability in the crenarchaeon
  publication-title: BMC Mol Biol
  doi: 10.1186/s12867-015-0030-z
– volume: 3
  start-page: 688
  year: 2014
  end-page: 701
  ident: CR9
  article-title: Identification of the minimal replicon and the origin of replication of the crenarchaeal plasmid pRN1
  publication-title: Microbiologyopen
  doi: 10.1002/mbo3.198
– volume: 189
  start-page: 2683
  year: 2007
  end-page: 2691
  ident: CR78
  article-title: Disruption of a sugar transporter gene cluster in a hyperthermophilic archaeon using a host-marker system based on antibiotic resistance
  publication-title: J Bacteriol
  doi: 10.1128/JB.01692-06
– volume: 79
  start-page: 117
  year: 2015
  end-page: 152
  ident: CR126
  article-title: Archaeal extrachromosomal genetic elements
  publication-title: Microbiol Mol Biol Rev
  doi: 10.1128/MMBR.00042-14
– volume: 482
  start-page: 331
  year: 2012
  end-page: 338
  ident: CR129
  article-title: RNA-guided genetic silencing systems in bacteria and archaea
  publication-title: Nature
  doi: 10.1038/nature10886
– volume: 2
  start-page: 391
  year: 1998
  end-page: 393
  ident: CR58
  article-title: plasmids pRN1 and pRN2 share distant but common evolutionary ancestry
  publication-title: Extremophiles
  doi: 10.1007/s007920050083
– volume: 281
  start-page: 27378
  year: 2006
  end-page: 27388
  ident: CR15
  article-title: Identification of the missing links in prokaryotic pentose oxidation pathways: evidence for enzyme recruitment
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M605549200
– volume: 3
  start-page: e00549
  year: 2015
  end-page: 15
  ident: CR79
  article-title: Complete genome sequence of strain 98/2 and evolved derivatives
  publication-title: Genome Announc
– volume: 89
  start-page: 7645
  year: 1992
  end-page: 7649
  ident: CR107
  article-title: The particle SSV1 from the extremely thermophilic archaeon is a virus: demonstration of infectivity and of transfection with viral DNA
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.89.16.7645
– volume: 38
  start-page: 253
  year: 2011
  end-page: 259
  ident: CR62
  article-title: Deletion of the topoisomerase III gene in the hyperthermophilic archaeon results in slow growth and defects in cell cycle control
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2011.05.001
– volume: 40
  start-page: 2470
  year: 2012
  end-page: 2480
  ident: CR31
  article-title: Modulation of CRISPR locus transcription by the repeat-binding protein Cbp1 in
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkr1111
– volume: 6
  start-page: 222
  year: 1998
  end-page: 228
  ident: CR7
  article-title: Transcription and translation in archaea: a mosaic of eukaryal and bacterial features
  publication-title: Trends Microbiol
  doi: 10.1016/S0966-842X(98)01281-5
– volume: 71
  start-page: 3889
  year: 2005
  end-page: 3899
  ident: CR102
  article-title: Improved and versatile transformation system allowing multiple genetic manipulations of the hyperthermophilic archaeon
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.71.7.3889-3899.2005
– volume: 34
  start-page: 217
  year: 1999
  end-page: 226
  ident: CR5
  article-title: The genetic element pSSVx of the extremely thermophilic crenarchaeon is a hybrid between a plasmid and a virus
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.1999.01573.x
– volume: 34
  start-page: e114
  year: 2006
  end-page: e114
  ident: CR6
  article-title: A spreadable, non-integrative and high copy number shuttle vector for based on the genetic element pSSVx from
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkl615
– volume: 183
  start-page: 2943
  year: 2001
  end-page: 2946
  ident: CR93
  article-title: Characterization of intragenic recombination in a hyperthermophilic archaeon via conjugational DNA exchange
  publication-title: J Bacteriol
  doi: 10.1128/JB.183.9.2943-2946.2001
– volume: 286
  start-page: 21643
  year: 2011
  end-page: 21656
  ident: CR65
  article-title: Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE)
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M111.238485
– volume: 39
  start-page: 99
  year: 2011
  end-page: 103
  ident: CR82
  article-title: Archaeal promoter architecture and mechanism of gene activation: figure 1
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0390099
– volume: 188
  start-page: 7141
  year: 2006
  end-page: 7150
  ident: CR104
  article-title: Regulation of mercury resistance in the crenarchaeote
  publication-title: J Bacteriol
  doi: 10.1128/JB.00558-06
– volume: 42
  start-page: 5993
  year: 2014
  end-page: 6011
  ident: CR25
  article-title: Structural and functional studies of Stf76 from the plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku215
– volume: 499
  start-page: 431
  year: 2013
  end-page: 437
  ident: CR96
  article-title: Insights into the phylogeny and coding potential of microbial dark matter
  publication-title: Nature
  doi: 10.1038/nature12352
– volume: 7
  start-page: 1902
  year: 2016
  ident: CR28
  article-title: Genome sequencing of sp. A20 from costa rica and comparative analyses of the putative pathways of carbon, nitrogen, and sulfur metabolism in various strains
  publication-title: Front Microbiol
– volume: 125
  start-page: 259
  year: 1980
  end-page: 269
  ident: CR147
  article-title: The group: taxonomy on the basis of the structure of DNA-dependent RNA polymerases
  publication-title: Arch Microbiol
  doi: 10.1007/BF00446886
– volume: 35
  start-page: 141
  year: 1996
  end-page: 144
  ident: CR57
  article-title: Complete nucleotide sequence of the multicopy plasmid pRN1
  publication-title: Plasmid
  doi: 10.1006/plas.1996.0016
– volume: 41
  start-page: 10509
  year: 2013
  end-page: 10517
  ident: CR73
  article-title: Unexpectedly broad target recognition of the CRISPR-mediated virus defence system in the archaeon
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkt767
– volume: 56
  start-page: 35
  year: 2006
  end-page: 45
  ident: CR90
  article-title: pIT3, a cryptic plasmid isolated from the hyperthermophilic crenarchaeon IT3
  publication-title: Plasmid
  doi: 10.1016/j.plasmid.2006.02.002
– volume: 154
  start-page: 295
  year: 2003
  end-page: 302
  ident: CR116
  article-title: Relationships between fuselloviruses infecting the extremely thermophilic archaeon : SSV1 and SSV2
  publication-title: Res Microbiol
  doi: 10.1016/S0923-2508(03)00074-3
– volume: 80
  start-page: 481
  year: 2011
  end-page: 491
  ident: CR74
  article-title: activity of CRISPR-mediated virus defence in a hyperthermophilic archaeon
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2011.07586.x
– volume: 5
  start-page: 506
  year: 2015
  end-page: 520
  ident: CR134
  article-title: pTC plasmids from species in the geothermal area of Tengchong, China: genomic conservation and naturally-occurring variations as a result of transposition by mobile genetic elements
  publication-title: Life
  doi: 10.3390/life5010506
– volume: 87
  start-page: 1088
  year: 2013
  end-page: 1099
  ident: CR30
  article-title: A novel interference mechanism by a type IIIB CRISPR-Cmr module in
  publication-title: Mol Microbiol
  doi: 10.1111/mmi.12152
– volume: 78
  start-page: 5630
  year: 2012
  end-page: 5637
  ident: CR83
  article-title: A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.00855-12
– volume: 353
  start-page: aad5147
  year: 2016
  ident: CR81
  article-title: Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
  publication-title: Science
  doi: 10.1126/science.aad5147
– volume: 189
  start-page: 4305
  year: 2007
  end-page: 4309
  ident: CR119
  article-title: Flagellar motility and structure in the hyperthermoacidophilic archaeon
  publication-title: J Bacteriol
  doi: 10.1128/JB.00042-07
– volume: 3
  start-page: 214
  year: 2012
  ident: CR125
  article-title: Versatile genetic tool box for the crenarchaeote
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2012.00214
– volume: 180
  start-page: 3237
  year: 1998
  end-page: 3240
  ident: CR19
  article-title: An autonomously replicating transforming vector for
  publication-title: J Bacteriol
– volume: 25
  start-page: 196
  year: 2015
  end-page: 205
  ident: CR52
  article-title: Improvement of a shuttle vector for heterologous gene expression in
  publication-title: J Microbiol Biotechnol
  doi: 10.4014/jmb.1407.07043
– volume: 152
  start-page: 1951
  year: 2006
  end-page: 1968
  ident: CR35
  article-title: Two novel conjugative plasmids from a single strain of
  publication-title: Microbiol
  doi: 10.1099/mic.0.28861-0
– volume: 187
  start-page: 4992
  year: 2005
  end-page: 4999
  ident: CR21
  article-title: The genome of , a model organism of the crenarchaeota
  publication-title: J Bacteriol
  doi: 10.1128/JB.187.14.4992-4999.2005
– volume: 6
  start-page: 245
  year: 2008
  end-page: 252
  ident: CR13
  article-title: Mesophilic crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota
  publication-title: Nat Rev Micro
  doi: 10.1038/nrmicro1852
– volume: 113
  start-page: 2496
  year: 2016
  end-page: 2501
  ident: CR122
  article-title: The archaeal Ced system imports DNA
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1513740113
– volume: 6
  start-page: 23
  year: 2015
  ident: CR2
  article-title: The archaellum: how archaea swim
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2015.00023
– volume: 57
  start-page: 487
  year: 2003
  end-page: 516
  ident: CR39
  article-title: Archaeal DNA replication: eukaryal proteins in a bacterial context
  publication-title: Annu Rev Microbiol
  doi: 10.1146/annurev.micro.57.030502.090709
– volume: 37
  start-page: 42
  year: 2009
  end-page: 45
  ident: CR66
  article-title: Molecular biology of the pRN1 plasmid from
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0370042
– volume: 79
  start-page: 5539
  year: 2013
  end-page: 5549
  ident: CR138
  article-title: Augmenting the genetic toolbox for with a stringent positive selectable marker for agmatine prototrophy
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01608-13
– volume: 10
  start-page: e1001265
  year: 2012
  ident: CR17
  article-title: Patterns of gene flow define species of thermophilic archaea
  publication-title: PLoS Biol
  doi: 10.1371/journal.pbio.1001265
– volume: 48
  start-page: 1241
  year: 2003
  end-page: 1252
  ident: CR55
  article-title: A reporter gene system for the hyperthermophilic archaeon based on a selectable and integrative shuttle vector
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2003.03509.x
– volume: 38
  start-page: 261
  year: 2011
  end-page: 269
  ident: CR68
  article-title: Development of pyrF-based gene knockout systems for genome-wide manipulation of the archaea and
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2011.05.003
– volume: 15
  start-page: 67
  year: 2011
  end-page: 76
  ident: CR70
  article-title: Single-stranded DNA binding activity of XPBI, but not XPBII, from causes double-stranded DNA melting
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0338-z
– volume: 20
  start-page: 139
  year: 2016
  end-page: 148
  ident: CR118
  article-title: Disruption of the gene encoding restriction endonuclease SuaI and development of a host-vector system for the thermoacidophilic archaeon
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0807-0
– volume: 84
  start-page: 54
  year: 1972
  end-page: 68
  ident: CR14
  article-title: Sulfolobus: a new genus of sulfur-oxidizing bacteria living at low pH and high temperature
  publication-title: Archiv Mikrobiol
  doi: 10.1007/BF00408082
– volume: 303
  start-page: 449
  year: 2000
  end-page: 454
  ident: CR88
  article-title: Evolution of the family of pRN plasmids and their integrase-mediated insertion into the chromosome of the crenarchaeon
  publication-title: J Mol Biol
  doi: 10.1006/jmbi.2000.4160
– volume: 177
  start-page: 4417
  year: 1995
  end-page: 4426
  ident: CR106
  article-title: A multicopy plasmid of the extremely thermophilic archaeon effects its transfer to recipients by mating
  publication-title: J Bacteriol
  doi: 10.1128/jb.177.15.4417-4426.1995
– volume: 76
  start-page: 3308
  year: 2010
  end-page: 3313
  ident: CR124
  article-title: Shuttle vector-based transformation system for
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01951-09
– volume: 55
  start-page: 422
  year: 2012
  end-page: 433
  ident: CR87
  article-title: Archaeal viruses—novel, diverse and enigmatic
  publication-title: Sci China Life Sci
  doi: 10.1007/s11427-012-4325-8
– volume: 182
  start-page: 2574
  year: 2000
  end-page: 2581
  ident: CR77
  article-title: High spontaneous mutation rate in the hyperthermophilic archaeon is mediated by transposable elements
  publication-title: J Bacteriol
  doi: 10.1128/JB.182.9.2574-2581.2000
– volume: 376
  start-page: 634
  year: 2008
  end-page: 644
  ident: CR95
  article-title: The archaeal XPB protein is a ssDNA-dependent ATPase with a novel partner
  publication-title: J Mol Biol
  doi: 10.1016/j.jmb.2007.12.019
– volume: 50
  start-page: 470
  year: 2001
  end-page: 478
  ident: CR29
  article-title: Environmental diversity of bacteria and archaea
  publication-title: Syst Biol
  doi: 10.1080/106351501750435040
– volume: 14
  start-page: 453
  year: 2010
  end-page: 463
  ident: CR23
  article-title: Transcription termination in the plasmid/virus hybrid pSSVx from
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0325-4
– volume: 18
  start-page: 93
  year: 1996
  end-page: 104
  ident: CR149
  article-title: General vectors for archaeal hyperthermophiles: strategies based on a mobile intron and a plasmid
  publication-title: FEMS Microbiol Rev
  doi: 10.1111/j.1574-6976.1996.tb00229.x
– volume: 2
  start-page: 928
  year: 2013
  end-page: 937
  ident: CR120
  article-title: Molecular analysis of the UV-inducible pili operon from
  publication-title: Microbiologyopen
  doi: 10.1002/mbo3.128
– volume: 87
  start-page: 4576
  year: 1990
  end-page: 4579
  ident: CR131
  article-title: Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.87.12.4576
– volume: 29
  start-page: 2059
  year: 2010
  end-page: 2069
  ident: CR132
  article-title: Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4
  publication-title: EMBO J
  doi: 10.1038/emboj.2010.101
– volume: 41
  start-page: 458
  year: 2013
  end-page: 462
  ident: CR140
  article-title: : a model system for evolutionary genomics
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST20120338
– volume: 190
  start-page: 217
  year: 2008
  end-page: 230
  ident: CR10
  article-title: Genetic tools for spp.: vectors and first applications
  publication-title: Arch Microbiol
  doi: 10.1007/s00203-008-0392-4
– volume: 74
  start-page: 928
  year: 2009
  end-page: 939
  ident: CR84
  article-title: An upstream activation element exerting differential transcriptional activation on an archaeal promoter
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2009.06908.x
– volume: 185
  start-page: 210
  year: 2003
  end-page: 220
  ident: CR101
  article-title: Targeted gene disruption by homologous recombination in the hyperthermophilic archaeon KOD1
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.1.210-220.2003
– volume: 34
  start-page: 4515
  year: 2006
  end-page: 4526
  ident: CR33
  article-title: Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkl623
– volume: 3
  start-page: 195
  year: 2012
  ident: CR47
  article-title: Genetics techniques for
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2012.00195
– volume: 193
  start-page: 1672
  year: 2011
  end-page: 1680
  ident: CR45
  article-title: Genome analyses of icelandic strains of , model organisms for genetic and virushost interaction studies
  publication-title: J Bacteriol
  doi: 10.1128/JB.01487-10
– volume: 435
  start-page: 157
  year: 2011
  end-page: 166
  ident: CR24
  article-title: C68 from the plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family
  publication-title: Biochem J
  doi: 10.1042/BJ20101334
– volume: 74
  start-page: 5088
  year: 1977
  end-page: 5090
  ident: CR130
  article-title: Phylogenetic structure of the prokaryotic domain: the primary kingdoms
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.74.11.5088
– start-page: 151
  year: 2008
  end-page: 156
  ident: CR108
  article-title: Host-vector systems for hyperthermophilic archaeon
  publication-title: Microbes and the Environment: Perspective and Challenges
– volume: 16
  start-page: 609
  year: 1993
  end-page: 628
  ident: CR146
  article-title: Screening for , their plasmids and their viruses in icelandic solfataras
  publication-title: Syst Appl Microbiol
  doi: 10.1016/S0723-2020(11)80333-4
– volume: 11
  start-page: 102
  year: 2012
  end-page: 111
  ident: CR49
  article-title: Dissection of the functional domains of an archaeal Holliday junction helicase
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2011.10.009
– volume: 187
  start-page: 805
  year: 2005
  end-page: 809
  ident: CR46
  article-title: Conjugational genetic exchange in the hyperthermophilic archaeon : intragenic recombination with minimal dependence on marker separation
  publication-title: J Bacteriol
  doi: 10.1128/JB.187.2.805-809.2005
– volume: 10
  start-page: 671
  year: 2013
  end-page: 678
  ident: CR72
  article-title: CRISPR-mediated defense mechanisms in the hyperthermophilic archaeal genus
  publication-title: RNA Biol
  doi: 10.4161/rna.24154
– volume: 1
  start-page: 183
  year: 1997
  end-page: 192
  ident: CR4
  article-title: Shuttle vectors for hyperthermophilic archaea
  publication-title: Extremophiles
  doi: 10.1007/s007920050032
– volume: 10
  start-page: 738
  year: 2013
  end-page: 748
  ident: CR86
  article-title: Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in
  publication-title: RNA Biol
  doi: 10.4161/rna.23798
– volume: 8
  start-page: 669
  year: 2005
  end-page: 676
  ident: CR59
  article-title: Archaeal DNA replication and repair
  publication-title: Curr Opin Microbiol
  doi: 10.1016/j.mib.2005.10.001
– volume: 197
  start-page: 2941
  year: 2015
  end-page: 2951
  ident: CR121
  article-title: DNA processing proteins involved in the UV-induced stress response of
  publication-title: J Bacteriol
  doi: 10.1128/JB.00344-15
– volume: 6
  start-page: 3161
  year: 2016
  end-page: 3168
  ident: CR137
  article-title: Efficient CRISPR-mediated post-transcriptional gene silencing in a hyperthermophilic archaeon using multiplexed crRNA expression
  publication-title: G3 (Bethesda)
– volume: 17
  start-page: 1381
  year: 2011
  end-page: 1392
  ident: CR71
  article-title: VapC6, a ribonucleolytic toxin regulates thermophilicity in the crenarchaeote
  publication-title: RNA
  doi: 10.1261/rna.2679911
– volume: 80
  start-page: 949
  year: 1998
  end-page: 957
  ident: CR27
  article-title: Structure-function studies on β-glycosidase from . Molecular bases of thermostability
  publication-title: Biochimie
  doi: 10.1016/S0300-9084(00)88892-6
– volume: 25
  start-page: 103
  year: 2015
  end-page: 112
  ident: CR53
  article-title: DNA repair in hyperthermophilic and hyperradioresistant microorganisms
  publication-title: Curr Opin Microbiol
  doi: 10.1016/j.mib.2015.05.010
– volume: 152
  start-page: 1307
  year: 1999
  end-page: 1314
  ident: CR60
  article-title: Molecular analysis of pDL10 from Acidianus ambivalens reveals a family of related plasmids from extremely thermophilic and acidophilic archaea
  publication-title: Genetics
– volume: 206
  start-page: 131
  year: 2002
  end-page: 141
  ident: CR16
  article-title: Mobile elements in archaeal genomes
  publication-title: FEMS Microbiol Lett
  doi: 10.1016/S0378-1097(01)00504-3
– volume: 43
  start-page: 406
  year: 2015
  end-page: 417
  ident: CR85
  article-title: An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku1302
– volume: 182
  start-page: 7014
  year: 2000
  end-page: 7020
  ident: CR117
  article-title: pING family of conjugative plasmids from the extremely thermophilic archaeon : insights into recombination and conjugation in crenarchaeota
  publication-title: J Bacteriol
  doi: 10.1128/JB.182.24.7014-7020.2000
– volume: 4
  start-page: 811
  year: 1985
  end-page: 816
  ident: CR18
  article-title: Insensitivity of archaebacterial ribosomes to protein synthesis inhibitors. Evolutionary implications
  publication-title: EMBO J
– volume: 2
  start-page: 417
  year: 1998
  end-page: 425
  ident: CR109
  article-title: Genetic profile of pNOB8 from : the first conjugative plasmid from an archaeon
  publication-title: Extremophiles
  doi: 10.1007/s007920050087
– volume: 159
  start-page: 1198
  year: 2013
  end-page: 1208
  ident: CR105
  article-title: Role of MerH in mercury resistance in the archaeon
  publication-title: Microbiology
  doi: 10.1099/mic.0.065854-0
– volume: 41
  start-page: 405
  year: 2013
  end-page: 410
  ident: CR142
  article-title: Genetic manipulation in and functional analysis of DNA repair genes
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST20120285
– volume: 37
  start-page: 92
  year: 2009
  end-page: 96
  ident: CR111
  article-title: Genetic analyses in the hyperthermophilic archaeon
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0370092
– volume: 20
  start-page: 785
  year: 2016
  end-page: 793
  ident: CR135
  article-title: Distinct catalytic activity and in vivo roles of the ExoIII and EndoIV AP endonucleases from
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0867-1
– volume: 79
  start-page: 35
  year: 2011
  end-page: 49
  ident: CR44
  article-title: Dynamic properties of the CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2010.07452.x
– volume: 20
  start-page: 537
  year: 2016
  end-page: 546
  ident: CR112
  article-title: Knockout and functional analysis of two DExD/H-box family helicase genes in REY15A
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0847-5
– volume: 44
  start-page: 4233
  year: 2016
  end-page: 4242
  ident: CR67
  article-title: Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugated species
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkw286
– volume: 3
  start-page: 2165
  year: 1984
  end-page: 2168
  ident: CR76
  article-title: SAV 1, a temperate u.v.-inducible DNA virus-like particle from the archaebacterium isolate B12
  publication-title: EMBO^J
– volume: 1
  start-page: 231
  year: 2004
  end-page: 239
  ident: CR40
  article-title: Genomic comparison of archaeal conjugative plasmids from
  publication-title: Archaea
  doi: 10.1155/2004/151926
– volume: 188
  start-page: 4198
  year: 2006
  end-page: 4206
  ident: CR92
  article-title: Mutations and rearrangements in the genome of P2
  publication-title: J Bacteriol
  doi: 10.1128/JB.00061-06
– volume: 8
  start-page: 123
  year: 2001
  end-page: 140
  ident: CR56
  article-title: Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, strain7
  publication-title: DNA Res
  doi: 10.1093/dnares/8.4.123
– volume: 18
  start-page: 473
  year: 2014
  end-page: 489
  ident: CR26
  article-title: Molecular biology of fuselloviruses and their satellites
  publication-title: Extremophiles
  doi: 10.1007/s00792-014-0634-0
– volume: 186
  start-page: 427
  year: 2004
  end-page: 437
  ident: CR103
  article-title: Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon by use of gene disruption
  publication-title: J Bacteriol
  doi: 10.1128/JB.186.2.427-437.2004
– volume: 40
  start-page: 225
  year: 2001
  end-page: 234
  ident: CR48
  article-title: Cell cycle regulation in the hyperthermophilic crenarchaeon
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2001.02377.x
– volume: 43
  start-page: 405
  year: 2016
  end-page: 413
  ident: CR113
  article-title: Structure-based genetic analysis of Hel308a in the hyperthermophilic archaeon
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2016.03.003
– volume: 185
  start-page: 772
  year: 2003
  end-page: 778
  ident: CR12
  article-title: Development of a gene knockout system for the halophilic archaeon by use of the gene
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.3.772-778.2003
– volume: 82
  start-page: 3070
  year: 2016
  end-page: 3081
  ident: CR141
  article-title: The /6-methylpurine counterselection system and its applications in genetic studies of the hyperthermophilic archaeon
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.00455-16
– volume: 43
  start-page: 1044
  year: 2015
  end-page: 1055
  ident: CR69
  article-title: Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR spacer acquisition
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku1383
– volume: 98
  start-page: 7835
  year: 2001
  end-page: 7840
  ident: CR110
  article-title: The complete genome of the crenarchaeon P2
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.141222098
– volume: 6
  start-page: 1613
  year: 2012
  end-page: 1616
  ident: CR75
  article-title: Genomic evidence of rapid, global-scale gene flow in a species
  publication-title: ISME J
  doi: 10.1038/ismej.2012.20
– volume: 200
  start-page: 97
  year: 2001
  end-page: 102
  ident: CR91
  article-title: Independent replication of the plasmids pRN1 and pRN2 in the archaeon
  publication-title: FEMS Microbiol Lett
  doi: 10.1111/j.1574-6968.2001.tb10699.x
– volume: 44
  start-page: e34
  year: 2016
  end-page: e34
  ident: CR63
  article-title: Harnessing type I and type III CRISPR-Cas systems for genome editing
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkv1044
– volume: 55
  start-page: 261
  year: 2012
  end-page: 267
  ident: CR127
  article-title: RadA paralog, stRadC2, is involved in DNA recombination via interaction with RadA and Hjc
  publication-title: Sci China Life Sci
  doi: 10.1007/s11427-012-4292-0
– volume: 5
  start-page: 783
  year: 2015
  end-page: 817
  ident: CR37
  article-title: CRISPR-Cas adaptive immune systems of the : unravelling their complexity and diversity
  publication-title: Life
  doi: 10.3390/life5010783
– volume: 35
  start-page: e88
  year: 2007
  end-page: e88
  ident: CR8
  article-title: Small multicopy, non-integrative shuttle vectors based on the plasmid pRN1 for and , model organisms of the (cren-)archaea
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkm449
– volume: 156
  start-page: 3386
  year: 2010
  end-page: 3397
  ident: CR139
  article-title: Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method
  publication-title: Microbiol
  doi: 10.1099/mic.0.042523-0
– volume: 363
  start-page: 124
  year: 2007
  end-page: 133
  ident: CR128
  article-title: A novel Sulfolobus non-conjugative extrachromosomal genetic element capable of integration into the host genome and spreading in the presence of a fusellovirus
  publication-title: Virology
  doi: 10.1016/j.virol.2007.01.035
– volume: 2
  start-page: 131
  year: 1998
  end-page: 140
  ident: CR145
  article-title: Genetic elements in the extremely thermophilic archaeon Sulfolobus
  publication-title: Extremophiles
  doi: 10.1007/s007920050052
– volume: 40
  start-page: 533
  year: 2013
  end-page: 542
  ident: CR64
  article-title: Knockouts of RecA-like proteins RadC1 and RadC2 have distinct responses to DNA damage agents in
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2013.05.004
– volume: 152
  start-page: 1397
  year: 1999
  end-page: 1405
  ident: CR115
  article-title: Genetic requirements for the function of the archaeal virus SSV1 in : construction and testing of viral shuttle vectors
  publication-title: Genetics
– volume: 35
  start-page: 577
  year: 2011
  end-page: 608
  ident: CR61
  article-title: Model organisms for genetics in the domain Archaea: methanogens, halophiles, and
  publication-title: FEMS Microbiol Rev
  doi: 10.1111/j.1574-6976.2011.00265.x
– volume: 106
  start-page: 8605
  year: 2009
  end-page: 8610
  ident: CR94
  article-title: Biogeography of the pan-genome
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0808945106
– volume: 23
  start-page: 801
  year: 2006
  end-page: 808
  ident: CR98
  article-title: The DNA repair helicases XPD and FancJ have essential ironsulfur domains
  publication-title: Mol Cell
  doi: 10.1016/j.molcel.2006.07.019
– volume: 13
  start-page: 735
  year: 2009
  end-page: 746
  ident: CR32
  article-title: Unmarked gene deletion and host-vector system for the hyperthermophilic crenarchaeon
  publication-title: Extremophiles
  doi: 10.1007/s00792-009-0254-2
– volume: 19
  start-page: 505
  year: 2015
  end-page: 514
  ident: CR50
  article-title: Genetic analysis of the Holliday junction resolvases Hje and Hjc in
  publication-title: Extremophiles
  doi: 10.1007/s00792-015-0734-5
– volume: 178
  start-page: 3396
  year: 1996
  end-page: 3398
  ident: CR99
  article-title: Differential antibiotic sensitivity determined by the large ribosomal subunit in thermophilic archaea
  publication-title: J Bacteriol
  doi: 10.1128/jb.178.11.3396-3398.1996
– volume: 1
  start-page: 319
  year: 2005
  end-page: 325
  ident: CR41
  article-title: Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 from
  publication-title: Archaea
  doi: 10.1155/2005/159218
– volume: 64
  start-page: 795
  year: 2007
  end-page: 806
  ident: CR148
  article-title: Identification of a system required for the functional surface localization of sugar binding proteins with class III signal peptides in
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2007.05697.x
– volume: 72
  start-page: 102
  year: 2006
  end-page: 111
  ident: CR3
  article-title: Production of recombinant and tagged proteins in the hyperthermophilic archaeon
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.72.1.102-111.2006
– volume: 78
  start-page: 568
  year: 2012
  end-page: 574
  ident: CR144
  article-title: Development of a simvastatin selection marker for a hyperthermophilic acidophile,
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.06095-11
– volume: 93
  start-page: 1965
  year: 2012
  end-page: 1974
  ident: CR80
  article-title: Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host
  publication-title: Appl Microbiol Biotechnol
  doi: 10.1007/s00253-011-3504-z
– volume: 189
  start-page: 6339
  year: 2007
  end-page: 6350
  ident: CR22
  article-title: Transcriptional analysis of the genetic element pSSVx: differential and temporal regulation of gene expression reveals correlation between transcription and replication
  publication-title: J Bacteriol
  doi: 10.1128/JB.00638-07
– volume: 98
  start-page: 7928
  year: 2001
  end-page: 7933
  ident: CR43
  article-title: Genetic fidelity under harsh conditions: analysis of spontaneous mutation in the thermoacidophilic archaeon
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.141113098
– volume: 185
  start-page: 4657
  year: 2003
  end-page: 4661
  ident: CR42
  article-title: Cytosine methylation by the I restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.15.4657-4661.2003
– volume: 158
  start-page: 1513
  year: 2012
  end-page: 1522
  ident: CR143
  article-title: A broadly applicable gene knockout system for the thermoacidophilic archaeon based on simvastatin selection
  publication-title: Microbiol
  doi: 10.1099/mic.0.058289-0
– volume: 185
  start-page: 482
  year: 2003
  end-page: 488
  ident: CR133
  article-title: Targeted disruption of the α-amylase gene in the hyperthermophilic archaeon
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.2.482-488.2003
– volume: 14
  start-page: 249
  year: 2010
  end-page: 259
  ident: CR11
  article-title: Inducible and constitutive promoters for genetic systems in
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0304-9
– volume: 3
  start-page: 130010
  year: 2013
  end-page: 130010
  ident: CR54
  article-title: Genomics and genetics of LAL14/1, a model hyperthermophilic archaeon
  publication-title: Open Biol
  doi: 10.1098/rsob.130010
– volume: 42
  start-page: 5280
  year: 2014
  end-page: 5288
  ident: CR136
  article-title: CRISPR-mediated targeted mRNA degradation in the archaeon
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku161
– volume: 7
  start-page: 191
  year: 2015
  end-page: 204
  ident: CR89
  article-title: Rooting the domain archaea by phylogenomic analysis supports the foundation of the new kingdom proteoarchaeota
  publication-title: Genome Biol Evol
  doi: 10.1093/gbe/evu274
– volume: 3
  start-page: 485
  year: 2013
  end-page: 496
  ident: CR100
  article-title: Specificity and function of archaeal DNA replication initiator proteins
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2013.01.002
– volume: 2
  start-page: 145
  year: 2008
  end-page: 149
  ident: CR1
  article-title: Conditions for gene disruption by homologous recombination of exogenous DNA into the genome
  publication-title: Archaea
  doi: 10.1155/2008/948014
– volume: 287
  start-page: 113
  year: 2008
  end-page: 120
  ident: CR36
  article-title: Agmatine is essential for the cell growth of
  publication-title: FEMS Microbiol Lett
  doi: 10.1111/j.1574-6968.2008.01303.x
– volume: 521
  start-page: 173
  year: 2015
  end-page: 179
  ident: CR114
  article-title: Complex archaea that bridge the gap between prokaryotes and eukaryotes
  publication-title: Nature
  doi: 10.1038/nature14447
– volume: 48
  start-page: 361
  year: 2003
  end-page: 371
  ident: CR97
  article-title: An archaeal XPF repair endonuclease dependent on a heterotrimeric PCNA
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2003.03444.x
– volume: 52
  start-page: 73
  year: 2006
  end-page: 116
  ident: CR20
  article-title: Archaeal habitats—from the extreme to the ordinary
  publication-title: Can J Microbiol
  doi: 10.1139/w05-147
– volume: 39
  start-page: 51
  year: 2011
  end-page: 57
  ident: CR38
  article-title: CRISPR-based immune systems of the : complexity and diversity
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0390051
– volume: 187
  start-page: 4992
  year: 2005
  ident: 355_CR21
  publication-title: J Bacteriol
  doi: 10.1128/JB.187.14.4992-4999.2005
– volume: 8
  start-page: 123
  year: 2001
  ident: 355_CR56
  publication-title: DNA Res
  doi: 10.1093/dnares/8.4.123
– volume: 499
  start-page: 431
  year: 2013
  ident: 355_CR96
  publication-title: Nature
  doi: 10.1038/nature12352
– start-page: 151
  volume-title: Microbes and the Environment: Perspective and Challenges
  year: 2008
  ident: 355_CR108
– volume: 182
  start-page: 7014
  year: 2000
  ident: 355_CR117
  publication-title: J Bacteriol
  doi: 10.1128/JB.182.24.7014-7020.2000
– volume: 1
  start-page: 231
  year: 2004
  ident: 355_CR40
  publication-title: Archaea
  doi: 10.1155/2004/151926
– volume: 44
  start-page: e34
  year: 2016
  ident: 355_CR63
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkv1044
– volume: 8
  start-page: 669
  year: 2005
  ident: 355_CR59
  publication-title: Curr Opin Microbiol
  doi: 10.1016/j.mib.2005.10.001
– volume: 3
  start-page: e00549
  year: 2015
  ident: 355_CR79
  publication-title: Genome Announc
– volume: 287
  start-page: 113
  year: 2008
  ident: 355_CR36
  publication-title: FEMS Microbiol Lett
  doi: 10.1111/j.1574-6968.2008.01303.x
– volume: 5
  start-page: 506
  year: 2015
  ident: 355_CR134
  publication-title: Life
  doi: 10.3390/life5010506
– volume: 125
  start-page: 259
  year: 1980
  ident: 355_CR147
  publication-title: Arch Microbiol
  doi: 10.1007/BF00446886
– volume: 43
  start-page: 1044
  year: 2015
  ident: 355_CR69
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku1383
– volume: 20
  start-page: 537
  year: 2016
  ident: 355_CR112
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0847-5
– volume: 5
  start-page: 783
  year: 2015
  ident: 355_CR37
  publication-title: Life
  doi: 10.3390/life5010783
– volume: 29
  start-page: 2059
  year: 2010
  ident: 355_CR132
  publication-title: EMBO J
  doi: 10.1038/emboj.2010.101
– volume: 40
  start-page: 533
  year: 2013
  ident: 355_CR64
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2013.05.004
– volume: 4
  start-page: 811
  year: 1985
  ident: 355_CR18
  publication-title: EMBO J
  doi: 10.1002/j.1460-2075.1985.tb03702.x
– volume: 74
  start-page: 928
  year: 2009
  ident: 355_CR84
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2009.06908.x
– volume: 98
  start-page: 7835
  year: 2001
  ident: 355_CR110
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.141222098
– volume: 35
  start-page: 141
  year: 1996
  ident: 355_CR57
  publication-title: Plasmid
  doi: 10.1006/plas.1996.0016
– volume: 1
  start-page: 183
  year: 1997
  ident: 355_CR4
  publication-title: Extremophiles
  doi: 10.1007/s007920050032
– volume: 35
  start-page: 577
  year: 2011
  ident: 355_CR61
  publication-title: FEMS Microbiol Rev
  doi: 10.1111/j.1574-6976.2011.00265.x
– volume: 376
  start-page: 634
  year: 2008
  ident: 355_CR95
  publication-title: J Mol Biol
  doi: 10.1016/j.jmb.2007.12.019
– volume: 76
  start-page: 3308
  year: 2010
  ident: 355_CR124
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01951-09
– volume: 6
  start-page: 3161
  year: 2016
  ident: 355_CR137
  publication-title: G3 (Bethesda)
  doi: 10.1534/g3.116.032482
– volume: 185
  start-page: 210
  year: 2003
  ident: 355_CR101
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.1.210-220.2003
– volume: 14
  start-page: 453
  year: 2010
  ident: 355_CR23
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0325-4
– volume: 189
  start-page: 2683
  year: 2007
  ident: 355_CR78
  publication-title: J Bacteriol
  doi: 10.1128/JB.01692-06
– volume: 3
  start-page: 130010
  year: 2013
  ident: 355_CR54
  publication-title: Open Biol
  doi: 10.1098/rsob.130010
– volume: 72
  start-page: 102
  year: 2006
  ident: 355_CR3
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.72.1.102-111.2006
– volume: 13
  start-page: 735
  year: 2009
  ident: 355_CR32
  publication-title: Extremophiles
  doi: 10.1007/s00792-009-0254-2
– volume: 37
  start-page: 92
  year: 2009
  ident: 355_CR111
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0370092
– volume: 87
  start-page: 4576
  year: 1990
  ident: 355_CR131
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.87.12.4576
– volume: 42
  start-page: 5280
  year: 2014
  ident: 355_CR136
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku161
– volume: 41
  start-page: 458
  year: 2013
  ident: 355_CR140
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST20120338
– volume: 35
  start-page: e88
  year: 2007
  ident: 355_CR8
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkm449
– volume: 152
  start-page: 1307
  year: 1999
  ident: 355_CR60
  publication-title: Genetics
  doi: 10.1093/genetics/152.4.1307
– volume: 521
  start-page: 173
  year: 2015
  ident: 355_CR114
  publication-title: Nature
  doi: 10.1038/nature14447
– volume: 3
  start-page: 195
  year: 2012
  ident: 355_CR47
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2012.00195
– volume: 185
  start-page: 482
  year: 2003
  ident: 355_CR133
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.2.482-488.2003
– volume: 39
  start-page: 99
  year: 2011
  ident: 355_CR82
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0390099
– volume: 152
  start-page: 1397
  year: 1999
  ident: 355_CR115
  publication-title: Genetics
  doi: 10.1093/genetics/152.4.1397
– volume: 37
  start-page: 42
  year: 2009
  ident: 355_CR66
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0370042
– volume: 113
  start-page: 2496
  year: 2016
  ident: 355_CR122
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1513740113
– volume: 80
  start-page: 949
  year: 1998
  ident: 355_CR27
  publication-title: Biochimie
  doi: 10.1016/S0300-9084(00)88892-6
– volume: 188
  start-page: 4198
  year: 2006
  ident: 355_CR92
  publication-title: J Bacteriol
  doi: 10.1128/JB.00061-06
– volume: 20
  start-page: 785
  year: 2016
  ident: 355_CR135
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0867-1
– volume: 2
  start-page: 391
  year: 1998
  ident: 355_CR58
  publication-title: Extremophiles
  doi: 10.1007/s007920050083
– volume: 79
  start-page: 5539
  year: 2013
  ident: 355_CR138
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01608-13
– volume: 52
  start-page: 73
  year: 2006
  ident: 355_CR20
  publication-title: Can J Microbiol
  doi: 10.1139/w05-147
– volume: 55
  start-page: 422
  year: 2012
  ident: 355_CR87
  publication-title: Sci China Life Sci
  doi: 10.1007/s11427-012-4325-8
– volume: 48
  start-page: 1241
  year: 2003
  ident: 355_CR55
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2003.03509.x
– volume: 16
  start-page: 2
  year: 2015
  ident: 355_CR51
  publication-title: BMC Mol Biol
  doi: 10.1186/s12867-015-0030-z
– volume: 189
  start-page: 4305
  year: 2007
  ident: 355_CR119
  publication-title: J Bacteriol
  doi: 10.1128/JB.00042-07
– volume: 25
  start-page: 196
  year: 2015
  ident: 355_CR52
  publication-title: J Microbiol Biotechnol
  doi: 10.4014/jmb.1407.07043
– volume: 286
  start-page: 21643
  year: 2011
  ident: 355_CR65
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M111.238485
– volume: 105
  start-page: 8102
  year: 2008
  ident: 355_CR34
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0801980105
– volume: 57
  start-page: 487
  year: 2003
  ident: 355_CR39
  publication-title: Annu Rev Microbiol
  doi: 10.1146/annurev.micro.57.030502.090709
– volume: 64
  start-page: 795
  year: 2007
  ident: 355_CR148
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2007.05697.x
– volume: 15
  start-page: 67
  year: 2011
  ident: 355_CR70
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0338-z
– volume: 10
  start-page: e1001265
  year: 2012
  ident: 355_CR17
  publication-title: PLoS Biol
  doi: 10.1371/journal.pbio.1001265
– volume: 19
  start-page: 505
  year: 2015
  ident: 355_CR50
  publication-title: Extremophiles
  doi: 10.1007/s00792-015-0734-5
– volume: 48
  start-page: 361
  year: 2003
  ident: 355_CR97
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2003.03444.x
– volume: 178
  start-page: 3396
  year: 1996
  ident: 355_CR99
  publication-title: J Bacteriol
  doi: 10.1128/jb.178.11.3396-3398.1996
– volume: 50
  start-page: 470
  year: 2001
  ident: 355_CR29
  publication-title: Syst Biol
  doi: 10.1080/106351501750435040
– volume: 182
  start-page: 2574
  year: 2000
  ident: 355_CR77
  publication-title: J Bacteriol
  doi: 10.1128/JB.182.9.2574-2581.2000
– volume: 158
  start-page: 1513
  year: 2012
  ident: 355_CR143
  publication-title: Microbiol
  doi: 10.1099/mic.0.058289-0
– volume: 156
  start-page: 3386
  year: 2010
  ident: 355_CR139
  publication-title: Microbiol
  doi: 10.1099/mic.0.042523-0
– volume: 154
  start-page: 295
  year: 2003
  ident: 355_CR116
  publication-title: Res Microbiol
  doi: 10.1016/S0923-2508(03)00074-3
– volume: 435
  start-page: 157
  year: 2011
  ident: 355_CR24
  publication-title: Biochem J
  doi: 10.1042/BJ20101334
– volume: 44
  start-page: 4233
  year: 2016
  ident: 355_CR67
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkw286
– volume: 3
  start-page: 485
  year: 2013
  ident: 355_CR100
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2013.01.002
– volume: 188
  start-page: 7141
  year: 2006
  ident: 355_CR104
  publication-title: J Bacteriol
  doi: 10.1128/JB.00558-06
– volume: 84
  start-page: 54
  year: 1972
  ident: 355_CR14
  publication-title: Archiv Mikrobiol
  doi: 10.1007/BF00408082
– volume: 78
  start-page: 568
  year: 2012
  ident: 355_CR144
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.06095-11
– volume: 18
  start-page: 473
  year: 2014
  ident: 355_CR26
  publication-title: Extremophiles
  doi: 10.1007/s00792-014-0634-0
– volume: 1
  start-page: 319
  year: 2005
  ident: 355_CR41
  publication-title: Archaea
  doi: 10.1155/2005/159218
– volume: 200
  start-page: 97
  year: 2001
  ident: 355_CR91
  publication-title: FEMS Microbiol Lett
  doi: 10.1111/j.1574-6968.2001.tb10699.x
– volume: 6
  start-page: 23
  year: 2015
  ident: 355_CR2
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2015.00023
– volume: 281
  start-page: 27378
  year: 2006
  ident: 355_CR15
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M605549200
– volume: 25
  start-page: 103
  year: 2015
  ident: 355_CR53
  publication-title: Curr Opin Microbiol
  doi: 10.1016/j.mib.2015.05.010
– volume: 193
  start-page: 1672
  year: 2011
  ident: 355_CR45
  publication-title: J Bacteriol
  doi: 10.1128/JB.01487-10
– volume: 78
  start-page: 5630
  year: 2012
  ident: 355_CR83
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.00855-12
– volume: 6
  start-page: 222
  year: 1998
  ident: 355_CR7
  publication-title: Trends Microbiol
  doi: 10.1016/S0966-842X(98)01281-5
– volume: 42
  start-page: 5993
  year: 2014
  ident: 355_CR25
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku215
– volume: 2
  start-page: 928
  year: 2013
  ident: 355_CR120
  publication-title: Microbiologyopen
  doi: 10.1002/mbo3.128
– volume: 157
  start-page: 2808
  year: 2011
  ident: 355_CR123
  publication-title: Microbiol
  doi: 10.1099/mic.0.051862-0
– volume: 353
  start-page: aad5147
  year: 2016
  ident: 355_CR81
  publication-title: Science
  doi: 10.1126/science.aad5147
– volume: 177
  start-page: 4417
  year: 1995
  ident: 355_CR106
  publication-title: J Bacteriol
  doi: 10.1128/jb.177.15.4417-4426.1995
– volume: 71
  start-page: 3889
  year: 2005
  ident: 355_CR102
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.71.7.3889-3899.2005
– volume: 43
  start-page: 405
  year: 2016
  ident: 355_CR113
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2016.03.003
– volume: 18
  start-page: 93
  year: 1996
  ident: 355_CR149
  publication-title: FEMS Microbiol Rev
  doi: 10.1111/j.1574-6976.1996.tb00229.x
– volume: 159
  start-page: 1198
  year: 2013
  ident: 355_CR105
  publication-title: Microbiology
  doi: 10.1099/mic.0.065854-0
– volume: 6
  start-page: 245
  year: 2008
  ident: 355_CR13
  publication-title: Nat Rev Micro
  doi: 10.1038/nrmicro1852
– volume: 10
  start-page: 671
  year: 2013
  ident: 355_CR72
  publication-title: RNA Biol
  doi: 10.4161/rna.24154
– volume: 363
  start-page: 124
  year: 2007
  ident: 355_CR128
  publication-title: Virology
  doi: 10.1016/j.virol.2007.01.035
– volume: 185
  start-page: 4657
  year: 2003
  ident: 355_CR42
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.15.4657-4661.2003
– volume: 10
  start-page: 738
  year: 2013
  ident: 355_CR86
  publication-title: RNA Biol
  doi: 10.4161/rna.23798
– volume: 3
  start-page: 2165
  year: 1984
  ident: 355_CR76
  publication-title: EMBO^J
– volume: 303
  start-page: 449
  year: 2000
  ident: 355_CR88
  publication-title: J Mol Biol
  doi: 10.1006/jmbi.2000.4160
– volume: 41
  start-page: 10509
  year: 2013
  ident: 355_CR73
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkt767
– volume: 98
  start-page: 7928
  year: 2001
  ident: 355_CR43
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.141113098
– volume: 189
  start-page: 6339
  year: 2007
  ident: 355_CR22
  publication-title: J Bacteriol
  doi: 10.1128/JB.00638-07
– volume: 87
  start-page: 1088
  year: 2013
  ident: 355_CR30
  publication-title: Mol Microbiol
  doi: 10.1111/mmi.12152
– volume: 74
  start-page: 5088
  year: 1977
  ident: 355_CR130
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.74.11.5088
– volume: 56
  start-page: 35
  year: 2006
  ident: 355_CR90
  publication-title: Plasmid
  doi: 10.1016/j.plasmid.2006.02.002
– volume: 186
  start-page: 427
  year: 2004
  ident: 355_CR103
  publication-title: J Bacteriol
  doi: 10.1128/JB.186.2.427-437.2004
– volume: 39
  start-page: 51
  year: 2011
  ident: 355_CR38
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST0390051
– volume: 79
  start-page: 117
  year: 2015
  ident: 355_CR126
  publication-title: Microbiol Mol Biol Rev
  doi: 10.1128/MMBR.00042-14
– volume: 185
  start-page: 772
  year: 2003
  ident: 355_CR12
  publication-title: J Bacteriol
  doi: 10.1128/JB.185.3.772-778.2003
– volume: 206
  start-page: 131
  year: 2002
  ident: 355_CR16
  publication-title: FEMS Microbiol Lett
  doi: 10.1016/S0378-1097(01)00504-3
– volume: 14
  start-page: 249
  year: 2010
  ident: 355_CR11
  publication-title: Extremophiles
  doi: 10.1007/s00792-010-0304-9
– volume: 41
  start-page: 405
  year: 2013
  ident: 355_CR142
  publication-title: Biochm Soc Trans
  doi: 10.1042/BST20120285
– volume: 2
  start-page: 145
  year: 2008
  ident: 355_CR1
  publication-title: Archaea
  doi: 10.1155/2008/948014
– volume: 7
  start-page: 1902
  year: 2016
  ident: 355_CR28
  publication-title: Front Microbiol
– volume: 40
  start-page: 2470
  year: 2012
  ident: 355_CR31
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkr1111
– volume: 93
  start-page: 1965
  year: 2012
  ident: 355_CR80
  publication-title: Appl Microbiol Biotechnol
  doi: 10.1007/s00253-011-3504-z
– volume: 190
  start-page: 217
  year: 2008
  ident: 355_CR10
  publication-title: Arch Microbiol
  doi: 10.1007/s00203-008-0392-4
– volume: 79
  start-page: 35
  year: 2011
  ident: 355_CR44
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2010.07452.x
– volume: 40
  start-page: 225
  year: 2001
  ident: 355_CR48
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.2001.02377.x
– volume: 152
  start-page: 1951
  year: 2006
  ident: 355_CR35
  publication-title: Microbiol
  doi: 10.1099/mic.0.28861-0
– volume: 38
  start-page: 261
  year: 2011
  ident: 355_CR68
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2011.05.003
– volume: 187
  start-page: 805
  year: 2005
  ident: 355_CR46
  publication-title: J Bacteriol
  doi: 10.1128/JB.187.2.805-809.2005
– volume: 16
  start-page: 609
  year: 1993
  ident: 355_CR146
  publication-title: Syst Appl Microbiol
  doi: 10.1016/S0723-2020(11)80333-4
– volume: 34
  start-page: 4515
  year: 2006
  ident: 355_CR33
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkl623
– volume: 3
  start-page: 214
  year: 2012
  ident: 355_CR125
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2012.00214
– volume: 7
  start-page: 191
  year: 2015
  ident: 355_CR89
  publication-title: Genome Biol Evol
  doi: 10.1093/gbe/evu274
– volume: 2
  start-page: 417
  year: 1998
  ident: 355_CR109
  publication-title: Extremophiles
  doi: 10.1007/s007920050087
– volume: 197
  start-page: 2941
  year: 2015
  ident: 355_CR121
  publication-title: J Bacteriol
  doi: 10.1128/JB.00344-15
– volume: 55
  start-page: 261
  year: 2012
  ident: 355_CR127
  publication-title: Sci China Life Sci
  doi: 10.1007/s11427-012-4292-0
– volume: 6
  start-page: 1613
  year: 2012
  ident: 355_CR75
  publication-title: ISME J
  doi: 10.1038/ismej.2012.20
– volume: 106
  start-page: 8605
  year: 2009
  ident: 355_CR94
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0808945106
– volume: 11
  start-page: 102
  year: 2012
  ident: 355_CR49
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2011.10.009
– volume: 23
  start-page: 801
  year: 2006
  ident: 355_CR98
  publication-title: Mol Cell
  doi: 10.1016/j.molcel.2006.07.019
– volume: 3
  start-page: 688
  year: 2014
  ident: 355_CR9
  publication-title: Microbiologyopen
  doi: 10.1002/mbo3.198
– volume: 80
  start-page: 481
  year: 2011
  ident: 355_CR74
  publication-title: Mol Microbiol
  doi: 10.1111/j.1365-2958.2011.07586.x
– volume: 34
  start-page: e114
  year: 2006
  ident: 355_CR6
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkl615
– volume: 482
  start-page: 331
  year: 2012
  ident: 355_CR129
  publication-title: Nature
  doi: 10.1038/nature10886
– volume: 43
  start-page: 406
  year: 2015
  ident: 355_CR85
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku1302
– volume: 89
  start-page: 7645
  year: 1992
  ident: 355_CR107
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.89.16.7645
– volume: 183
  start-page: 2943
  year: 2001
  ident: 355_CR93
  publication-title: J Bacteriol
  doi: 10.1128/JB.183.9.2943-2946.2001
– volume: 2
  start-page: 131
  year: 1998
  ident: 355_CR145
  publication-title: Extremophiles
  doi: 10.1007/s007920050052
– volume: 180
  start-page: 3237
  year: 1998
  ident: 355_CR19
  publication-title: J Bacteriol
  doi: 10.1128/JB.180.12.3237-3240.1998
– volume: 82
  start-page: 3070
  year: 2016
  ident: 355_CR141
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.00455-16
– volume: 20
  start-page: 139
  year: 2016
  ident: 355_CR118
  publication-title: Extremophiles
  doi: 10.1007/s00792-016-0807-0
– volume: 17
  start-page: 1381
  year: 2011
  ident: 355_CR71
  publication-title: RNA
  doi: 10.1261/rna.2679911
– volume: 34
  start-page: 217
  year: 1999
  ident: 355_CR5
  publication-title: Mol Microbiol
  doi: 10.1046/j.1365-2958.1999.01573.x
– volume: 38
  start-page: 253
  year: 2011
  ident: 355_CR62
  publication-title: J Genet Genomics
  doi: 10.1016/j.jgg.2011.05.001
SSID ssj0000330277
Score 2.3020585
SecondaryResourceType review_article
Snippet Archaea represents the third domain of life, with the information-processing machineries more closely resembling those of eukaryotes than the machineries of...
SourceID proquest
pubmed
crossref
springer
chongqing
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 370
SubjectTerms Biomedical and Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats
CRISPR
DNA fingerprints
Gene Silencing
Genes, Archaeal
Genetic engineering
Genetic Markers
Genetic Vectors
Life Sciences
Microorganisms
Review
Sulfolobus - genetics
SummonAdditionalLinks – databaseName: Springer Open Access Hybrid - NESLI2 2011-2012
  dbid: 40G
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV27T94wED8VKiQWRFseAVoZqVNLpDzsxB4rBEWVygJIbJHj2DB8XwLky8DIf86d86AIisSSIfbZSe7i-9n3AvhOGe8Uqp0wwrUONyhOhtIkIjQc-e9yIypvPf97mp1c8D-X4nKI425Hb_fRJOlX6qdgt5gn5CaJO2BUkqFcgo-UTYxEmUe_p4OVKCVTnC-qkpGvIQr0aM18bRTKqXDd1Fe3OONz3fQCcL4wlnoddLwOawN4ZL96bn-CD7b-DCt9Ocn7L_BAOaSxiS3G83LcBjNEpQxXYDoHnN0zwnvz5oaOUQybkzdeX9epnbesceysmzkkLLv2gLqypkaaq35YPSN6iqqicCu623kaxJ21T7lk9QacHx-dH56EQ4mF0IhULELJK5kZHUlunItkpYyMdCyVzaxVLkflnnKTCl3p1AorK614WrkEYZ12JWLDTVium9puA6twydV5XCZOc14KUVYiSktdprm0NEMAu9N3Lm76TBpFRkZgpTi2RuOXL8yQnJxqZMyKp7TKxLiCHNKIcYUM4MdEMo73Rue9kZ3F8JO2Bb4ngjG8qAD2p2b8vchmomvbdNSH6vjEKo8D2OrFYJrNh_3yLAng5ygX_wz-v0fZeVfvXVhNCEh4X6E9WF7cdfYrwqBF-c2L_SNl6P3_
  priority: 102
  providerName: Springer Nature
Title Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea
URI http://lib.cqvip.com/qk/60112X/201704/672039940.html
https://link.springer.com/article/10.1007/s11427-016-0355-8
https://www.ncbi.nlm.nih.gov/pubmed/28251462
https://www.proquest.com/docview/1899768999
https://www.proquest.com/docview/1873721971
Volume 60
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB71ISQuCMqjoe3KSJyAiDzsxDmhFloKiApBK-0tcvwoh91kSzaHHvnnzDiPgip6iZTY40SeiefzzHgG4CVlvCtQ7YQRrnW4QXEylDoRoebIf5drYbz3_OtZdnrBP8_FfDC4tUNY5bgm-oXaNJps5G9j3BggNEY88251FVLVKPKuDiU0NmGbUpeRVOfzfLKxRCl55Xx9lYzCDlG2R8emPz0X84TiLnFLjVo3lJRe4WdTX16h0vhXTd3Cnrf8pl4dnTyEBwOOZIc94x_Bhq134F5fWfL6MfymdNLYxNaj6Rx3xAwBKsPFmEyCi2tG0G_ZrMiiotmSAvP6Ek_tsmWNYz-6hUPCqmvfUFfW1Ehz2Q-rFkRPB6zo5BU97TwNQtDaZ1-y6gmcnxyfvz8Nh2oLoRapWIeSG5lpFUmunYukKbSMFM66zawtXI56PuU6Fcqo1AorjSp4alyCCE-5CmHiU9iqm9ruAjO4-qo8rhKnOK-EqIyI0kpVaS4tvSGAvWmey1WfVKPMyB9cFBxbo3HmSz3kKadyGYvyJsMyMa6k2DRiXCkDeDWRjOPd0Xl_ZGc5_K9teSNdAbyYmvFPI_eJqm3TUR8q6RMXeRzAs14Mprf5E8A8SwJ4PcrFX4P_71Oe3_0pe3A_IRDh44T2YWv9q7MHCIHW1Qw2efRx5qV9BttHx2ffvuPdh09f8HqRHP4BMY4GQw
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtR3LbtQwcFQVIbgg3qQtYCS4ABF52IlzQAgB1ZY-LizS3izHscthN9k2G6E98kH8IzPOJgVV9NZr7HGizHjeD4CX1PGuQLETRsjr0EBxMpQmEaHhiH-XG1H56PnxSTb5zr_OxGwLfg-1MJRWOfBEz6irxpCP_F2MhgGqxqjPfFiehTQ1iqKrwwiNniwO7fonmmzt-4PPiN9XSbL_ZfppEm6mCoRGpGIVSl7JzOhIcuNcJKvCyEjj6TaztnA5yrOUm1ToSqdWWFnpgqeVS1CT0a4sqM8BcvwbKHcjsvXyWT66dKKUgoB-nEtGWY54lYY4qi_Wi3lCaZ5owaOQDyV1c_jR1KdnKKP-lYqXVN1LYVov_fbvwp2N2so-9nR2D7ZsfR9u9oMs1w_gF3WvxiW2Gjz1aIAz1IcZ8n7yQM7XjDTNRbMkB45hC8oD7CdKtYuWNY596-YOAcuufUtbWVMjzGl_rJ4TPNVzUaEXPe08DGq8tW_2ZPVDmF4HGh7Bdt3U9gmwCpm9zuMycZrzUoiyElFa6jLNpaU3BLA7_me17Ht4qIzCz0XBcTUa_rwym7boNJ1jri4aOhPiFKXCEeKUDOD1CDKcd8XmvQGdasMeWnVBzAG8GJfxYlO0Rte26WgPTRCKizwO4HFPBuPbfMExz5IA3gx08dfh__uUnas_5TncmkyPj9TRwcnhLtxOSH_xKUp7sL067-xT1L5W5TNP8wzUNd-xPxefPxo
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Jb9UwEB5BEaiXirWEtmAkTkDULHZiHyvoU9kqJFqpt8jxUg7vJa8kOfTYf85MtoIKSFxyiD124rE9nz0bwCuKeKdQ7IQR7nV4QPEylCYRoeHIf58bYXvt-Zfj7OiUfzwTZ2Oe02aydp9UkoNPA0Vpqtr9tfX7145vMU_IZBJPwygwQ3kb7nByBsYJfZoczJcsUUpquT7BSkZ2hzi5J83mn1qh-Arf6-r8Anv_XU7dAJ83FKe9PFrch60RSLKDgfMP4JarHsLdIbXk5SO4onjSWMTa6e4cj8QMESrD3ZjuBJeXjLDfql7TlYphK7LMG3I8NauG1Z5965YeCcuueUtVWV0hzfnQrF4SPXlYkesVve16GsSgVR9-yenHcLI4PHl3FI7pFkIjUtGGkluZGR1JbryPpFVGRjqWymXOKZ-joE-5SYW2OnXCSasVT61PEOJpXyJOfAIbVV25p8Asbr86j8vEa85LIUororTUZZpLRz0EsDOPc7EeomoUGSmEleJYGk0jX5gxUDnly1gW1yGWiXEFGacR4woZwOuZZGrvH5V3J3YW44JtCvxPBGb4UAG8nItxqZH-RFeu7qgO5fSJVR4HsD1Mg7m33gWYZ0kAb6Z58Uvjf_uUZ_9V-wXc-_p-UXz-cPxpBzYTwhe9CdEubLQ_OreH6Kgtn_cr4Cc_HAVg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Genetic+technologies+for+extremely+thermophilic+microorganisms+of+Sulfolobus%2C+the+only+genetically+tractable+genus+of+crenarchaea&rft.jtitle=Science+China.+Life+sciences&rft.au=Peng%2C+Nan&rft.au=Han%2C+Wenyuan&rft.au=Li%2C+Yingjun&rft.au=Liang%2C+Yunxiang&rft.date=2017-04-01&rft.issn=1674-7305&rft.eissn=1869-1889&rft.volume=60&rft.issue=4&rft.spage=370&rft.epage=385&rft_id=info:doi/10.1007%2Fs11427-016-0355-8&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s11427_016_0355_8
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fimage.cqvip.com%2Fvip1000%2Fqk%2F60112X%2F60112X.jpg