Gut microbiota and oleoylethanolamide in the regulation of intestinal homeostasis

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1135157
• Main Authors: De Filippo, Carlotta, Costa, Alessia, Becagli, Maria Vittoria, Monroy, Mariela Mejia, Provensi, Gustavo, Passani, Maria Beatrice
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.04.2023
• Subjects: Diabetes Mellitus, Type 2; dysbiosis; Endocannabinoids - metabolism; Endocrinology; Gastrointestinal Microbiome - physiology; gut barrier permeability; Homeostasis; Humans; inflammation; intestinal physiology; metabolic diseases; obesity; intestinal physiology; gut barrier permeability; inflammation; metabolic diseases; obesity; dysbiosis

A vast literature strongly suggests that the endocannabinoid (eCB) system and related bioactive lipids (the paracannabinoid system) contribute to numerous physiological processes and are involved in pathological conditions such as obesity, type 2 diabetes, and intestinal inflammation. The gut paraca...