Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects - Burgess, Stephen; Thompson, Simon G. (American journal of epidemiology, 2015)
Keywords: Biomarkers - blood; Cardiovascular disease; Cardiovascular diseases; Causality; Cholesterol; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Coronary Disease - blood; Coronary Disease - diagnosis; Coronary Disease - epidemiology; Coronary Disease - genetics; Epidemiology; Genetic Pleiotropy - genetics; Genetic variance; Genetic Variation - genetics; Genetics; Genotype & phenotype; Humans; Lipids; Low density lipoprotein; Mathematical Computing; Mendelian Randomization Analysis - methods; Models, Genetic; Practice of Epidemiology; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Triglycerides - blood; United Kingdom - epidemiology; lipid fractions; epidemiologic methods; instrumental variables; Mendelian randomization; causal inference; pleiotropy