Mesenchymal Migration as a Therapeutic Target in Glioblastoma

• Published in: Journal of oncology Vol. 2010; no. 2010; pp. 1 - 17
• Main Authors: Zhong, Jessie, Paul, Andre, Kellie, Stewart J., O'Neill, Geraldine M.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Puplishing Corporation 01.01.2010; Hindawi Publishing Corporation
• Subjects: Review

Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the glioblastoma cells renders complete surgical excision difficult and contemporary adjuvant therapies have had little impact on long-term survival...