Mesenchymal Migration as a Therapeutic Target in Glioblastoma

Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the glioblastoma cells renders complete surgical excision difficult and contemporary adjuvant therapies have had little impact on long-term survival...

Full description

Saved in:
Bibliographic Details
Published inJournal of oncology Vol. 2010; no. 2010; pp. 1 - 17
Main Authors Zhong, Jessie, Paul, Andre, Kellie, Stewart J., O'Neill, Geraldine M.
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Puplishing Corporation 01.01.2010
Hindawi Publishing Corporation
Subjects
Review
Online AccessGet full text

Cover

Abstract Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the glioblastoma cells renders complete surgical excision difficult and contemporary adjuvant therapies have had little impact on long-term survival. Thus, deep infiltration and resistance to irradiation and chemotherapy remain a major cause of patient mortality. Modern therapies specifically targeted to this unique aspect of glioblastoma cell biology hold significant promise to substantially improve survival rates for glioblastoma patients. In the present paper, we focus on the role of adhesion signaling molecules and the actin cytoskeleton in the mesenchymal mode of motility that characterizes invading glioblastoma cells. We then review current approaches to targeting these elements of the glioblastoma cell migration machinery and discuss other aspects of cell migration that may improve the treatment of infiltrating glioblastoma.
AbstractList Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the glioblastoma cells renders complete surgical excision difficult and contemporary adjuvant therapies have had little impact on long-term survival. Thus, deep infiltration and resistance to irradiation and chemotherapy remain a major cause of patient mortality. Modern therapies specifically targeted to this unique aspect of glioblastoma cell biology hold significant promise to substantially improve survival rates for glioblastoma patients. In the present paper, we focus on the role of adhesion signaling molecules and the actin cytoskeleton in the mesenchymal mode of motility that characterizes invading glioblastoma cells. We then review current approaches to targeting these elements of the glioblastoma cell migration machinery and discuss other aspects of cell migration that may improve the treatment of infiltrating glioblastoma.
Author Paul, Andre
Kellie, Stewart J.
Zhong, Jessie
O'Neill, Geraldine M.
AuthorAffiliation 3 Oncology Department, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia
2 Discipline of Paediatrics and Child Health, The University of Sydney, Sydney, NSW 2006, Australia
1 Children's Cancer Research Unit, Kids Research Institute, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
AuthorAffiliation_xml – name: 2 Discipline of Paediatrics and Child Health, The University of Sydney, Sydney, NSW 2006, Australia
– name: 1 Children's Cancer Research Unit, Kids Research Institute, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
– name: 3 Oncology Department, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia
Author_xml – sequence: 1
  fullname: Zhong, Jessie
– sequence: 2
  fullname: Paul, Andre
– sequence: 3
  fullname: Kellie, Stewart J.
– sequence: 4
  fullname: O'Neill, Geraldine M.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/20652056$$D View this record in MEDLINE/PubMed
BookMark eNqF0U1rFEEQBuBGIuZDT56VuQnKmurv6YOCBI1Cgpf13NTM1Oy2zHSv3bNK_r2zTFziKadqqIeXLt5zdhJTJMZecnjPudaXAjhcKglciSfsjJvarmql4eTB-5Sdl_ITwChw5hk7FWC0AG3O2IdbKhTb7d2IQ3UbNhmnkGKFpcJqvaWMO9pPoa3WmDc0VSFW10NIzYBlSiM-Z097HAq9uJ8X7MeXz-urr6ub79ffrj7drFot9bRSDUflTEe87shICcoJ0_ZgRCehEbZ31lpTO3KaUBrVuK5rSdS2F11nWy4v2Mcld7dvRpp3cco4-F0OI-Y7nzD4_zcxbP0m_fbCgXbqEPDmPiCnX3sqkx9DaWkYMFLaF2-10tpZDY9LqQBqKd0s3y2yzamUTP3xPxz8oRl_aMYvzcz69cMTjvZfFTN4u4BtiB3-CY-kvVowzYR6PGJluZFa_gVtVaCX
CitedBy_id crossref_primary_10_1007_s12257_016_0625_3
crossref_primary_10_1007_s12035_014_8668_y
crossref_primary_10_1038_srep24912
crossref_primary_10_1371_journal_pcbi_1002556
crossref_primary_10_1038_s41598_018_22681_3
crossref_primary_10_1007_s10571_023_01393_x
crossref_primary_10_3390_mi15050559
crossref_primary_10_1093_neuonc_noab244
crossref_primary_10_1088_1367_2630_15_1_015021
crossref_primary_10_1007_s12035_012_8349_7
crossref_primary_10_3389_fnmol_2017_00420
crossref_primary_10_1158_0008_5472_CAN_13_3294
crossref_primary_10_3390_cancers11050631
crossref_primary_10_1002_anie_201309885
crossref_primary_10_1158_1078_0432_CCR_17_1549
crossref_primary_10_1021_acs_jproteome_5b00765
crossref_primary_10_1155_2014_386470
crossref_primary_10_1007_s10571_015_0293_4
crossref_primary_10_3390_cancers13143419
crossref_primary_10_3892_ijo_2017_4051
crossref_primary_10_3390_chemosensors8040095
crossref_primary_10_3892_or_2022_8431
crossref_primary_10_1093_carcin_bgu123
crossref_primary_10_3389_fonc_2020_00798
crossref_primary_10_1016_j_molmed_2018_07_003
crossref_primary_10_3390_ijms21228491
crossref_primary_10_1039_C6NR00147E
crossref_primary_10_1002_ange_201309885
crossref_primary_10_3390_ijms242216316
crossref_primary_10_3389_fnmol_2019_00066
crossref_primary_10_1002_jbm_a_35947
crossref_primary_10_1155_2013_248507
crossref_primary_10_1371_journal_pone_0171312
crossref_primary_10_1158_1535_7163_MCT_11_0977
crossref_primary_10_1016_j_semcancer_2015_04_007
crossref_primary_10_1016_j_bbcan_2013_07_001
crossref_primary_10_1186_s40478_021_01151_4
crossref_primary_10_1080_10408363_2018_1462759
crossref_primary_10_1186_s12987_021_00242_7
crossref_primary_10_1089_omi_2016_0142
crossref_primary_10_1186_s13041_019_0462_3
crossref_primary_10_1155_2010_174715
crossref_primary_10_1371_journal_pone_0051859
crossref_primary_10_2174_1874471011666180817122427
crossref_primary_10_3109_02688697_2014_887659
crossref_primary_10_3390_cancers11111651
crossref_primary_10_3390_cells12111459
crossref_primary_10_1002_jcp_24841
crossref_primary_10_1007_s12017_014_8309_7
crossref_primary_10_1038_s41598_019_51108_w
crossref_primary_10_3390_ijms20051137
crossref_primary_10_3892_mmr_2017_7888
crossref_primary_10_3389_fcell_2019_00066
crossref_primary_10_1002_adbi_201700221
crossref_primary_10_1007_s11064_021_03476_x
Cites_doi 10.1215/15228517-2009-012
10.1038/nrc1121
10.1083/jcb.200405156
10.1038/onc.2009.2
10.1097/00005072-199401000-00002
10.1007/s00401-007-0243-4
10.1126/science.270.5241.1500
10.1083/jcb.200111032
10.1002/mc.20297
10.1021/jm970832g
10.1158/1541-7786.MCR-05-0015
10.1038/ncb1094
10.1038/nrc1075
10.1016/S0002-9440(10)61225-4
10.1074/jbc.M404675200
10.1074/jbc.272.4.2446
10.1016/S0960-9822(00)00177-9
10.1016/j.drudis.2008.09.005
10.1227/01.NEU.0000245622.70344.BE
10.1074/jbc.274.35.24947
10.1128/MCB.16.10.5623
10.1017/S1740925X06000111
10.1586/ern.09.10
10.1056/NEJMoa043330
10.1007/s00018-007-6342-5
10.1111/j.1750-3639.2005.tb00115.x
10.1038/377539a0
10.1073/pnas.0307512101
10.1517/17425240903167942
10.1016/S0360-3016(98)00266-1
10.2174/138161209787846720
10.2174/157489207780832469
10.1128/MCB.21.22.7641-7652.2001
10.1016/j.tcb.2006.08.006
10.1016/j.ceb.2005.11.005
10.1002/(SICI)1097-0029(19981201)43:5<369::AID-JEMT3>3.0.CO;2-6
10.1038/onc.2008.137
10.1016/j.cellbi.2005.07.005
10.1083/jcb.200510115
10.1128/MCB.18.5.2571
10.1242/jcs.112.16.2677
10.1002/glia.20850
10.4161/cam.2.3.6578
10.1016/0092-8674(87)90104-8
10.1242/jcs.109.7.1787
10.1128/MCB.00857-08
10.1038/nrc2148
10.1083/jcb.153.7.1427
10.1073/pnas.0903035106
10.1038/nm0902-918
10.1016/S0092-8674(00)81280-5
10.1242/jcs.03314
10.1517/17425240902988470
10.1158/1078-0432.CCR-08-0797
10.1016/0092-8674(95)90370-4
10.1074/jbc.270.29.17437
10.1016/j.semcancer.2007.08.004
10.1080/07357900701577475
10.1097/00130404-200303000-00008
10.1158/0008-5472.CAN-07-2667
10.1016/j.molonc.2009.01.002
10.1038/ncb0807-858
10.1097/00005072-199611000-00005
10.1097/00001813-200304000-00008
10.1083/jcb.146.5.1107
10.1016/j.ijrobp.2005.11.014
10.1016/j.ceb.2003.11.001
10.1016/0360-3016(93)90203-8
10.1212/01.wnl.0000304121.57857.38
10.1038/35010517
10.1021/bm9010276
10.1101/gad.891601
10.1038/37656
10.1158/1541-7786.595.2.11
10.1007/s11060-004-2751-6
10.1038/sj.pcan.4500387
10.1083/jcb.200406063
10.1083/jcb.200609004
10.1200/JCO.2006.07.4807
10.1007/s12013-007-0036-3
10.1016/S0960-9822(00)00777-6
10.1002/1098-1136(200011)32:2<146::AID-GLIA40>3.0.CO;2-3
10.1038/nrc1886
10.1146/annurev.pharmtox.47.120505.105237
10.1056/NEJMoa012224
10.1083/jcb.140.4.961
10.1242/jcs.052704
10.1080/10623320600698037
10.1038/sj.onc.1206347
10.1002/ana.410360505
10.1128/MCB.15.2.954
10.1042/BJ20031041
10.3171/jns.2006.105.5.739
10.1002/ijc.23809
10.1073/pnas.92.20.9161
10.1126/science.277.5325.567
10.1097/nen.0b013e31804567d7
10.1016/S0165-6147(00)01596-0
10.1097/00006123-200108000-00022
10.1016/j.molmed.2005.06.007
10.1172/JCI115516
10.1016/0092-8674(92)90163-7
10.1182/blood-2006-05-023580
10.1074/jbc.271.42.26329
10.1007/s11060-005-6749-5
10.2174/138161206777947740
10.1126/science.275.5308.1943
10.1242/jcs.114.15.2713
10.1038/nrc839
10.1023/A:1006091608586
10.1126/science.290.5490.333
10.1056/NEJMoa043331
10.1056/NEJMra0708126
10.1091/mbc.E02-04-0244
10.1038/sj.onc.1208080
10.1200/JCO.2008.16.7510
10.1016/j.cub.2005.12.033
10.1023/A:1022983000355
10.1016/S0960-9822(00)00417-6
10.4161/cc.8.10.8490
10.1128/MCB.15.5.2635
10.1016/j.biocel.2008.08.021
10.1161/CIRCRESAHA.107.155655
10.1007/s10637-009-9326-5
10.1083/jcb.134.3.793
10.1073/pnas.84.19.6899
10.1128/MCB.17.12.6906
10.1083/jcb.140.1.211
10.1186/1756-9966-27-86
10.1200/JCO.2006.09.8376
10.1097/00005072-199702000-00009
10.1097/JTO.0b013e31819c78fb
10.1128/MCB.16.6.3169
10.1054/bjoc.2000.1316
10.1126/science.280.5369.1614
10.1159/000028975
10.1073/pnas.91.16.7727
10.1016/j.cell.2007.05.041
10.1038/370527a0
10.1083/jcb.144.6.1235
10.1007/s11060-007-9486-0
10.1158/0008-5472.CAN-05-0077
10.1038/309030a0
10.1091/mbc.E08-03-0319
10.1038/ng0497-356
10.1158/1535-7163.MCT-06-0698
10.4161/cam.3.4.9468
10.2353/ajpath.2007.070011
10.1038/sj.onc.1209199
10.1083/jcb.200703036
10.1158/1078-0432.CCR-04-1223
10.1007/s11060-009-9916-2
10.1016/S0962-8924(99)01714-6
10.1158/0008-5472.CAN-09-0347
10.1124/pr.107.07109
10.1073/pnas.98.4.1853
10.1038/ncb1762
10.1111/j.1750-3639.2000.tb00258.x
10.1021/ar800243b
10.1158/1078-0432.CCR-05-0722
10.1093/emboj/17.1.81
10.1038/ncb1626
10.1016/j.coph.2008.06.012
10.1002/14651858.CD007415
10.1002/jcb.21159
10.1016/j.humpath.2005.03.014
10.1093/annonc/mdm140
10.1200/JCO.2006.06.6514
10.1200/JCO.2005.23.622
10.1016/j.cell.2008.09.043
10.1242/jcs.00712
10.1242/jcs.111.11.1535
10.1016/j.nurt.2009.04.004
10.1074/jbc.M307526200
10.1083/jcb.131.4.989
10.1002/ijc.10265
10.1016/j.biocel.2004.01.013
10.1038/sj.onc.1203422
10.1212/WNL.4.9.718
10.1038/sj.onc.1202758
10.1038/nrc727
10.1081/CNV-200050453
10.1038/35025220
10.1097/00005072-199503000-00010
10.1101/gad.1596707
10.1074/jbc.R000028200
10.1083/jcb.200105109
10.1242/jcs.01631
10.1038/sj.neo.7900102
10.1093/neuonc/1.1.44
10.1016/S0960-9822(99)80286-3
10.1517/13543784.17.8.1225
10.1042/0264-6021:3460561
10.1083/jcb.153.3.569
10.1242/jcs.00792
10.1158/1535-7163.MCT-08-0629
10.1126/science.1092053
10.1083/jcb.200206043
10.1073/pnas.171076798
10.1186/1471-2202-9-S2-S4
10.1038/372786a0
10.1146/annurev.cellbio.12.1.463
10.1016/S0092-8674(00)80732-1
10.1371/journal.pmed.0050008
10.1002/cm.20053
10.1038/nrc822
10.2174/156800906776842948
10.1002/cm.20030
10.1007/s11060-008-9656-8
10.1227/00006123-199604000-00026
10.1093/carcin/22.10.1715
10.1002/pbc.20803
10.1158/1535-7163.MCT-08-0669
ContentType Journal Article
Contributor Paul, Andre
O'Neill, Geraldine M
Zhong, Jessie
Kellie, Stewart J
Contributor_xml – sequence: 1
  fullname: Zhong, Jessie
– sequence: 2
  fullname: Paul, Andre
– sequence: 3
  fullname: Kellie, Stewart J
– sequence: 4
  fullname: O'Neill, Geraldine M
Copyright Copyright © 2010
Copyright © 2010 Jessie Zhong et al. 2010
Copyright_xml – notice: Copyright © 2010
– notice: Copyright © 2010 Jessie Zhong et al. 2010
DBID ADJCN
AHFXO
RHU
RHW
RHX
NPM
AAYXX
CITATION
7X8
7TK
5PM
DOI 10.1155/2010/430142
DatabaseName الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals
معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete
Hindawi Publishing Complete
Hindawi Publishing Subscription Journals
Hindawi Publishing Open Access
PubMed
CrossRef
MEDLINE - Academic
Neurosciences Abstracts
PubMed Central (Full Participant titles)
DatabaseTitle PubMed
CrossRef
MEDLINE - Academic
Neurosciences Abstracts
DatabaseTitleList CrossRef
PubMed



Neurosciences Abstracts
Database_xml – sequence: 1
  dbid: RHX
  name: Hindawi Publishing Open Access
  url: http://www.hindawi.com/journals/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1687-8450
Editor Andl, Claudia D.
Editor_xml – sequence: 1
  givenname: Claudia D.
  surname: Andl
  fullname: Andl, Claudia D.
EndPage 17
ExternalDocumentID 10_1155_2010_430142
20652056
471635
Genre Journal Article
GroupedDBID ---
188
24P
29L
2UF
2WC
4.4
53G
5GY
5VS
7RV
7X7
8FI
8FJ
AAFWJ
AAJEY
AAWTL
ABDBF
ABUWG
ADBBV
ADJCN
ADRAZ
AFKRA
AHFXO
AINHJ
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
BENPR
CCPQU
CEFSP
CNMHZ
DIK
E3Z
EBD
EBS
EJD
EMOBN
ESX
F5P
FYUFA
GROUPED_DOAJ
GX1
H13
HMCUK
HYE
IAO
IEA
IHR
IHW
IL9
INH
INR
KQ8
M48
NAPCQ
O5R
O5S
OK1
PGMZT
PIMPY
RHU
RHX
RPM
TR2
TUS
UKHRP
UZ5
~8M
RHW
NPM
AAYXX
CITATION
7X8
7TK
5PM
ID FETCH-LOGICAL-c535t-4b1a496de18de63304926cf062d30b27f9777689e95ea364b9ddce287f2dd7c13
IEDL.DBID RPM
ISSN 1687-8450
IngestDate Tue Sep 17 21:15:11 EDT 2024
Fri Oct 25 00:03:28 EDT 2024
Fri Oct 25 00:22:18 EDT 2024
Fri Dec 06 05:55:06 EST 2024
Sat Sep 28 07:51:40 EDT 2024
Sun Jun 02 19:22:34 EDT 2024
Tue Nov 26 17:10:16 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2010
Language English
License This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
http://creativecommons.org/licenses/by/3.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c535t-4b1a496de18de63304926cf062d30b27f9777689e95ea364b9ddce287f2dd7c13
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
Academic Editor: Claudia D. Andl
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905941/
PMID 20652056
PQID 734008339
PQPubID 23479
PageCount 17
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_2905941
proquest_miscellaneous_754559750
proquest_miscellaneous_734008339
crossref_primary_10_1155_2010_430142
pubmed_primary_20652056
hindawi_primary_10_1155_2010_430142
emarefa_primary_471635
PublicationCentury 2000
PublicationDate 2010-01-01
PublicationDateYYYYMMDD 2010-01-01
PublicationDate_xml – month: 01
  year: 2010
  text: 2010-01-01
  day: 01
PublicationDecade 2010
PublicationPlace Cairo, Egypt
PublicationPlace_xml – name: Cairo, Egypt
– name: Egypt
PublicationTitle Journal of oncology
PublicationTitleAlternate J Oncol
PublicationYear 2010
Publisher Hindawi Puplishing Corporation
Hindawi Publishing Corporation
Publisher_xml – name: Hindawi Puplishing Corporation
– name: Hindawi Publishing Corporation
References (169) 2008; 26
(44) 2004; 70
TraceyE.BakerD.ChenW.StavrouE.BishopJ.Cancer in New South Wales: Incidence, Mortality and Prevalence, 20052007Sydney, AustraliaCancer Institute NSW
(58) 2009; 42
(67) 2008; 14
(203) 2006; 6
(52) 2003; 20
(209) 2008; 135
(127) 1992; 70
(70) 2006; 25
(152) 2008; 70
(155) 1991; 88
(229) 2008; 87
(24) 1999; 59
(13) 2007; 170
(214) 1989
(166) 2006; 59
(86) 2000; 10
(181) 2006; 64
(230) 2008; 7
(92) 2008; 8
(215) 2002; 2
(126) 2003; 302
(14) 1999; 1
(195) 1997; 272
(208) 2005; 29
(124) 2000; 10
(218) 1994; 4
(173) 2002; 62
(146) 2000; 83
(217) 2002; 2
(57) 1984; 309
(199) 2003; 14
(47) 1996; 12
(220) 1997; 277
(125) 1999; 18
(62) 2005; 11
(179) 2009; 69
(143) 2003; 14
(213) 2006; 6
(78) 1995; 55
(31) 2001; 22
(51) 2002; 2
(93) 1998; 17
(184) 2005; 11
(237) 2009; 6
(56) 2006; 12
(176) 2008; 26
(154) 2009; 11
(59) 1996; 55
(197) 2010; 11
(19) 1994; 54
(186) 2001; 98
(189) 1996; 75
(211) 2002; 62
(90) 2000; 19
(224) 2001; 155
(80) 1995; 15
(231) 2008; 123
(228) 2007; 66
(54) 2000; 3
(82) 1998; 18
(113) 2006; 16
(158) 2006; 13
(201) 2009; 3
(118) 2002; 159
(206) 2005; 60
(25) 2001; 15
(27) 1994; 53
(182) 2009; 3
(11) 2003; 3
(69) 2003; 9
(40) 2003; 3
(112) 2009; 122
(16) 1994; 91
(32) 2007; 48
(87) 2001; 21
(226) 2007; 6
(45) 1996; 84
(148) 2005; 15
(168) 2002; 98
(165) 2008; 27
(227) 2008; 10
(129) 2000; 290
(73) 1999; 112
(123) 2004; 377
(140) 1960; 84
(161) 2000; 407
(68) 2000; 33
(198) 2009; 9
(83) 1996; 271
(153) 2009; 9
(41) 2004; 16
(77) 1998; 140
(28) 1997; 3
(61) 2007; 177
(22) 2000; 2
(151) 2000; 2
(219) 1994; 370
(174) 2007; 46
(116) 1999; 97
(4) 2005; 352
(76) 1996; 109
(35) 2005; 75
(137) 2004; 166
(1) 2007; 64
(39) 2006; 2
(26) 1988; 48
(84) 1996; 16
(160) 1998; 4
(239) 2008; 9
(97) 2004; 279
(185) 2008; 27
(225) 2000; 10
(107) 2007; 179
(139) 1954; 4
(164) 2008; 17
(98) 2005; 3
(42) 2007; 101
(48) 1987; 51
(177) 2007; 67
(122) 1999; 144
(216) 2004; 101
(223) 1997; 15
(71) 2009; 95
(43) 1996; 38
(190) 2003; 22
(115) 1995; 81
(221) 2000; 346
(205) 2000; 32
(149) 2001; 61
(15) 2000; 60
(55) 2002; 8
(95) 2009; 29
(9) 2004; 36
(163) 1999; 42
(38) 2008; 19
(144) 2005; 11
(7) 1999; 43
(156) 2001; 49
(99) 2004; 23
(188) 2005; 23
(133) 1997; 390
(30) 1994; 36
(109) 1995; 131
(110) 2001; 276
(63) 2007; 2
(21) 1987; 84
(159) 2001; 98
(147) 2008
(172) 2007; 18
(222) 1997; 275
(232) 2007; 47
(96) 2003; 278
(18) 2006; 26
(60) 2003; 116
KayeA. H.LawsE. R.Historical perspectiveBrain Tumors1995New York, NY, USAChurchill Livingstone38
(100) 1998; 140
(187) 2008; 5
(106) 1999; 65
(34) 2005; 352
(53) 1999; 59
(178) 2004; 2
(66) 2005; 167
(204) 2007; 7
(50) 2009; 41
(121) 2007; 9
(202) 2008; 18
(8) 2006; 105
(103) 1995; 270
(17) 1997; 56
(134) 2009; 28
(135) 2005; 118
(102) 2009; 8
(91) 2008; 90
(104) 1995; 15
(117) 2006; 16
(94) 2007; 120
(89) 2004; 108
(150) 2009; 57
(142) 1993; 26
(235) 1999; 5
(193) 1998; 43
(191) 2009; 106
(108) 2001; 153
(212) 2003; 116
(234) 2009; 6
(119) 1995; 92
(192) 1995; 54
(75) 1995; 377
(157) 1996; 134
(170) 2007; 25
(37) 2002; 346
(130) 2001; 114
(46) 2001; 153
(194) 1999; 274
(162) 1995; 270
(65) 2007; 101
(200) 2005; 168
(131) 2002; 156
(141) 2008; 359
(171) 2007; 25
(196) 2003
(101) 1999; 146
(175) 2009
(3) 2006; 20
(105) 1994; 372
(85) 1997; 17
(74) 2004; 6
(79) 2007; 129
(167) 2006; 108
(236) 2008; 13
(33) 2007; 25
(128) 1999; 9
(2) 2007; 21
(233) 2008; 60
(29) 2006; 66
(81) 1996; 16
(20) 1997; 57
(12) 2007; 114
(6) 1998; 40
(23) 1998; 280
(88) 2007; 48
(180) 2009; 8
(210) 1999; 65
(136) 2006; 18
(238) 2009; 6
(64) 2005; 36
(72) 2007; 9
(114) 2004; 59
(207) 2006; 173
(120) 1998; 111
(111) 2001; 22
(10) 1998; 18
(49) 2009; 15
(183) 2009; 4
(132) 2008; 2
(145) 2005; 23
(36) 2000; 10
10445846 - Oncogene. 1999 Jul 1;18(26):3831-45
15094120 - Int J Biochem Cell Biol. 2004 Jun;36(6):1046-69
11504114 - Neurosurgery. 2001 Aug;49(2):380-9; discussion 390
9472046 - J Cell Biol. 1998 Feb 23;140(4):961-72
16504759 - Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1197-203
17522712 - Nat Rev Cancer. 2007 Jun;7(6):429-40
17121137 - J Neurosurg. 2006 Nov;105(5):739-44
19690143 - Cancer Res. 2009 Sep 1;69(17):6889-98
11331307 - J Cell Biol. 2001 Apr 30;153(3):569-84
3477813 - Proc Natl Acad Sci U S A. 1987 Oct;84(19):6899-903
11756467 - J Cell Biol. 2001 Dec 24;155(7):1129-35
11005565 - Neoplasia. 2000 Jul-Aug;2(4):306-14
11577014 - Carcinogenesis. 2001 Oct;22(10):1715-9
11929835 - Cancer Res. 2002 Apr 1;62(7):2131-40
17164291 - J Cell Sci. 2007 Jan 1;120(Pt 1):137-48
9616126 - Science. 1998 Jun 5;280(5369):1614-7
9858334 - Microsc Res Tech. 1998 Dec 1;43(5):369-78
11683406 - J Cell Sci. 2001 Aug;114(Pt 15):2713-22
16251422 - Am J Pathol. 2005 Nov;167(5):1379-87
9072974 - Science. 1997 Mar 28;275(5308):1943-7
9989517 - Int J Radiat Oncol Biol Phys. 1999 Jan 1;43(1):79-88
10320939 - Biochem Soc Symp. 1999;65:173-205
14521508 - Biochem J. 2004 Jan 15;377(Pt 2):327-37
16002336 - Trends Mol Med. 2005 Aug;11(8):353-61
11084341 - Curr Biol. 2000 Nov 2;10(21):1387-90
8999957 - J Biol Chem. 1997 Jan 24;272(4):2446-51
1721625 - J Clin Invest. 1991 Dec;88(6):1924-32
8832401 - J Cell Sci. 1996 Jul;109 ( Pt 7):1787-94
8387988 - Int J Radiat Oncol Biol Phys. 1993 May 20;26(2):239-44
19010848 - Clin Cancer Res. 2008 Nov 15;14(22):7330-9
8052651 - Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7727-31
8608589 - Cell. 1996 Feb 9;84(3):359-69
17942320 - Semin Cancer Biol. 2008 Feb;18(1):35-44
18669428 - N Engl J Med. 2008 Jul 31;359(5):492-507
17671451 - Nat Cell Biol. 2007 Aug;9(8):858-67
18215105 - PLoS Med. 2008 Jan 22;5(1):e8
9427743 - EMBO J. 1998 Jan 2;17(1):81-92
17219439 - Mol Carcinog. 2007 Jun;46(6):488-96
12972425 - J Biol Chem. 2003 Nov 21;278(47):46533-40
18984162 - Cell. 2008 Oct 31;135(3):510-23
19489579 - Acc Chem Res. 2009 Jul 21;42(7):969-80
9927060 - Cancer Res. 1999 Jan 15;59(2):442-9
9228007 - Science. 1997 Jul 25;277(5325):567-70
16728329 - Endothelium. 2006 Mar-Apr;13(2):113-35
17721515 - Nat Cell Biol. 2007 Sep;9(9):1046-56
8816475 - Mol Cell Biol. 1996 Oct;16(10):5623-33
11832530 - N Engl J Med. 2002 Feb 7;346(6):420-7
9331071 - Cancer Res. 1997 Oct 1;57(19):4183-6
16288224 - Oncogene. 2006 Mar 16;25(12):1721-32
18625340 - Curr Opin Pharmacol. 2008 Aug;8(4):427-32
7820549 - Curr Biol. 1994 Sep 1;4(9):798-806
17260089 - Cell Mol Life Sci. 2007 Feb;64(4):458-78
17442989 - J Clin Oncol. 2007 Apr 20;25(12):1470-5
12189386 - Nat Rev Cancer. 2002 Jun;2(6):442-54
9034372 - J Neuropathol Exp Neurol. 1997 Feb;56(2):180-5
19124607 - Mol Cell Biol. 2009 Mar;29(6):1506-14
14657486 - Science. 2003 Dec 5;302(5651):1704-9
19262107 - Cell Adh Migr. 2008 Jul-Sep;2(3):174-6
11604500 - Mol Cell Biol. 2001 Nov;21(22):7641-52
12631719 - Mol Biol Cell. 2003 Mar;14(3):1002-16
7568093 - Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9161-5
18848640 - Drug Discov Today. 2008 Dec;13(23-24):1099-106
9580561 - J Cell Sci. 1998 Jun;111 ( Pt 11):1535-44
16723991 - Nat Rev Cancer. 2006 Jun;6(6):449-58
15037300 - Curr Opin Cell Biol. 2004 Feb;16(1):14-23
15615780 - J Cell Sci. 2005 Jan 1;118(Pt 1):19-26
7566154 - Nature. 1995 Oct 12;377(6549):539-44
7997267 - Nature. 1994 Dec 22-29;372(6508):786-91
8052307 - Nature. 1994 Aug 18;370(6490):527-32
16651380 - J Cell Biol. 2006 May 8;173(3):395-404
16712460 - Curr Cancer Drug Targets. 2006 May;6(3):245-56
2509387 - Int J Cancer Suppl. 1989;4:69-75
18648907 - J Neurooncol. 2008 Nov;90(2):181-9
16461277 - Curr Biol. 2006 Feb 7;16(3):242-51
7987821 - Cancer Res. 1994 Dec 15;54(24):6321-4
19240653 - J Thorac Oncol. 2009 Apr;4(4):448-54
16203762 - Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6767-71
19538036 - Expert Opin Drug Deliv. 2009 Jul;6(7):705-18
18006843 - Cancer Res. 2007 Nov 15;67(22):10976-83
19190119 - Mol Cancer Ther. 2009 Feb;8(2):394-406
11425873 - J Cell Biol. 2001 Jun 25;153(7):1427-40
11920637 - Int J Cancer. 2002 Apr 10;98(5):690-7
17277694 - Neurosurgery. 2006 Dec;59(6):1304-12; discussion 1312
10675905 - Trends Cell Biol. 2000 Mar;10(3):111-9
9815715 - Clin Cancer Res. 1997 Apr;3(4):523-30
10698680 - Biochem J. 2000 Mar 15;346 Pt 3:561-76
10375527 - Curr Biol. 1999 Jun 17;9(12):640-8
17226777 - J Cell Biochem. 2007 Jul 1;101(4):805-15
7529876 - Mol Cell Biol. 1995 Feb;15(2):954-63
12835669 - Nat Rev Cancer. 2003 Jul;3(7):489-501
9892097 - J Neurooncol. 1998 Nov;40(2):151-60
19114005 - J Exp Clin Cancer Res. 2008 Dec 29;27:86
14743221 - Nat Cell Biol. 2004 Feb;6(2):154-61
17618441 - Acta Neuropathol. 2007 Aug;114(2):97-109
15128949 - Proc Natl Acad Sci U S A. 2004 May 18;101(20):7618-23
17974913 - Genes Dev. 2007 Nov 1;21(21):2683-710
9403696 - Nature. 1997 Dec 11;390(6660):632-6
10806474 - Nat Cell Biol. 2000 May;2(5):249-56
16961459 - Annu Rev Pharmacol Toxicol. 2007;47:323-55
19692590 - J Cell Sci. 2009 Sep 1;122(Pt 17):3037-49
9566877 - Mol Cell Biol. 1998 May;18(5):2571-85
19732031 - Expert Opin Drug Deliv. 2009 Oct;6(10):1017-32
11550301 - Neuro Oncol. 1999 Jan;1(1):44-51
16195804 - J Neurooncol. 2005 Dec;75(3):267-72
8824286 - J Biol Chem. 1996 Oct 18;271(42):26329-34
17470853 - J Clin Oncol. 2007 May 1;25(13):1637-8
7615549 - J Biol Chem. 1995 Jul 21;270(29):17437-41
10219243 - Cell. 1999 Apr 16;97(2):221-31
8939197 - J Neuropathol Exp Neurol. 1996 Nov;55(11):1143-9
13214273 - Neurology. 1954 Sep;4(9):718-21
17641225 - Circ Res. 2007 Sep 14;101(6):570-80
19541645 - Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10666-71
18852145 - Mol Cancer Ther. 2008 Oct;7(10):3420-8
12635172 - Nat Rev Cancer. 2002 Feb;2(2):91-100
16397228 - Cancer Res. 2006 Jan 1;66(1):159-67
17485491 - J Cell Biol. 2007 May 7;177(3):515-25
1643657 - Cell. 1992 Aug 7;70(3):389-99
9829725 - Clin Cancer Res. 1998 Nov;4(11):2625-34
10037179 - Clin Cancer Res. 1999 Feb;5(2):309-17
17201132 - Anticancer Res. 2006 Nov-Dec;26(6B):4191-4
15716379 - J Cell Biol. 2005 Feb 14;168(4):619-31
19234490 - Oncogene. 2009 Apr 2;28(13):1570-83
17703068 - Cell Biochem Biophys. 2007;48(1):54-72
15561776 - Mol Cancer Res. 2004 Nov;2(11):595-605
7537852 - Mol Cell Biol. 1995 May;15(5):2635-45
16021573 - Hum Pathol. 2005 Jun;36(6):665-9
10477763 - J Cell Biol. 1999 Sep 6;146(5):1107-16
12784878 - Cancer J. 2003 Mar-Apr;9(2):126-33
19355970 - Curr Pharm Des. 2009;15(12):1309-17
11096123 - J Biol Chem. 2001 Feb 16;276(7):4527-30
19191326 - Glia. 2009 Sep;57(12):1306-15
10087266 - J Cell Biol. 1999 Mar 22;144(6):1235-44
18981465 - J Clin Oncol. 2008 Dec 1;26(34):5610-7
2901288 - Cancer Res. 1988 Oct 1;48(19):5546-51
18560012 - Pharmacol Rev. 2008 Jun;60(2):196-209
16918408 - Curr Pharm Des. 2006;12(22):2723-47
18004504 - J Neurooncol. 2008 Mar;87(1):71-8
19560743 - Neurotherapeutics. 2009 Jul;6(3):539-46
15662725 - Cell Motil Cytoskeleton. 2005 Mar;60(3):153-65
11025423 - Pediatr Neurosurg. 2000 Jul;33(1):49-55
10713673 - Oncogene. 2000 Mar 2;19(10):1318-28
17456751 - Am J Pathol. 2007 May;170(5):1445-53
3315233 - Cell. 1987 Dec 4;51(5):813-9
18843749 - Cochrane Database Syst Rev. 2008 Oct 08;(4):CD007415
17766839 - Mol Cancer Ther. 2007 Sep;6(9):2505-14
16835373 - Blood. 2006 Nov 1;108(9):3035-44
11165670 - Trends Pharmacol Sci. 2001 Jan;22(1):32-9
15972849 - Mol Cancer Res. 2005 Jun;3(6):307-15
11504908 - Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10314-9
18259944 - Cancer Invest. 2008 Mar;26(2):145-51
19221171 - Neuro Oncol. 2009 Dec;11(6):747-56
17483698 - J Neuropathol Exp Neurol. 2007 May;66(5):405-17
18316689 - Neurology. 2008 Mar 4;70(10):779-87
19160483 - Nat Cell Biol. 2008 Sep;10(9):1027-38
7490299 - J Cell Biol. 1995 Nov;131(4):989-1002
16144931 - Clin Cancer Res. 2005 Sep 1;11(17):6270-9
16949823 - Trends Cell Biol. 2006 Oct;16(10):522-9
15362118 - Cell Motil Cytoskeleton. 2004 Oct;59(2):141-52
15221336 - Acta Neuropathol. 2004 Sep;108(3):224-30
12741679 - Clin Exp Metastasis. 2003;20(3):203-13
12094235 - Nat Rev Cancer. 2002 Jul;2(7):489-501
15674479 - J Neurooncol. 2004 Nov;70(2):217-28
17470857 - J Clin Oncol. 2007 May 1;25(13):1651-7
7796399 - Cancer Res. 1995 Jul 1;55(13):2752-5
6325925 - Nature. 1984 May 3-9;309(5963):30-3
8970735 - Annu Rev Cell Dev Biol. 1996;12:463-518
18221059 - Recent Pat Anticancer Drug Discov. 2007 Jun;2(2):143-58
9703890 - Anticancer Res. 1998 Jul-Aug;18(4A):2435-47
16301112 - Cell Biol Int. 2005 Nov;29(11):877-83
11008214 - Glia. 2000 Nov;32(2):146-54
15758009 - N Engl J Med. 2005 Mar 10;352(10):987-96
14587300 - Biochem Soc Symp. 2003;(70):277-85
16389942 - Brain Pathol. 2005 Oct;15(4):297-310
14576354 - J Cell Sci. 2003 Nov 15;116(Pt 22):4605-13
8707856 - J Cell Biol. 1996 Aug;134(3):793-9
15998902 - J Clin Oncol. 2005 Aug 10;23(23):5294-304
18798255 - Int J Cancer. 2008 Dec 1;123(11):2676-83
15489911 - Oncogene. 2004 Oct 18;23(48):7928-46
18504440 - Oncogene. 2008 Aug 28;27(37):4998-5010
10320936 - Biochem Soc Symp. 1999;65:111-23
16609952 - Pediatr Blood Cancer. 2007 Apr;48(4):403-7
12205444 - Nat Med. 2002 Sep;8(9):918-21
11559524 - Cancer Res. 2001 Sep 15;61(18):6624-8
9372922 - Mol Cell Biol. 1997 Dec;17(12):6906-14
11172040 - Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1853-8
7536630 - Cell. 1995 Apr 7;81(1):53-62
15813507 - Cancer Invest. 2005;23(2):138-44
12642872 - Oncogene. 2003 Mar 20;22(11):1688-702
18790075 - Int J Biochem Cell Biol. 2009 Feb;41(2):341-8
19436954 - J Neurooncol. 2009 Nov;95(2):151-63
10764044 - Brain Pathol. 2000 Apr;10(2):249-59
8649427 - Mol Cell Biol. 1996 Jun;16(6):3169-78
15337778 - J Cell Biol. 2004 Aug 30;166(5):697-708
10455171 - J Biol Chem. 1999 Aug 27;274(35):24947-52
7979217 - Ann Neurol. 1994 Nov;36(5):714-21
16337782 - Curr Opin Cell Biol. 2006 Feb;18(1):26-31
12679735 - Anticancer Drugs. 2003 Apr;14(4):305-12
12724734 - Nat Rev Cancer. 2003 May;3(5):362-74
19372747 - Cell Cycle. 2009 May 15;8(10):1484-7
8973477 - Lab Invest. 1996 Dec;75(6):819-26
18634584 - Neuron Glia Biol. 2006 May;2(2):105-14
10753747 - Curr Biol. 2000 Apr 6;10(7):401-4
11001068 - Nature. 2000 Sep 14;407(6801):249-57
16709036 - Neurosurg Focus. 2006 Apr 15;20(4
230
110
231
111
232
112
233
113
234
114
236
237
117
238
118
239
119
12
13
16
121
1
122
2
123
124
4
125
126
6
127
7
128
8
129
9
22
23
25
29
131
133
134
135
136
137
30
32
33
34
35
37
38
39
141
143
144
145
147
40
41
42
44
45
46
47
49
150
152
153
154
156
158
159
50
52
55
56
58
161
163
164
165
166
168
169
60
61
62
64
65
69
170
171
172
174
175
176
177
179
70
71
72
74
77
79
180
181
182
183
184
185
186
187
188
83
86
87
88
(5) 2007
190
191
193
194
195
197
198
199
(138) 1995
91
92
93
94
95
96
97
98
99
200
202
203
204
205
206
207
208
209
212
213
216
218
219
220
100
221
101
222
223
103
224
225
226
227
107
228
229
109
References_xml – volume: 47
  start-page: 323
  year: 2007
  end-page: 355
  ident: 232
  article-title: Drug targeting to the brain
– volume: 22
  start-page: 32
  issue: 1
  year: 2001
  end-page: 39
  ident: 111
  article-title: Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
– volume: 377
  start-page: 327
  issue: 2
  year: 2004
  end-page: 337
  ident: 123
  article-title: Rho GTPases have diverse effects on the organization of the actin filament system
– volume: 10
  start-page: 1027
  issue: 9
  year: 2008
  end-page: 1038
  ident: 227
  article-title: Identification of genes that regulate epithelial cell migration using an siRNA screening approach
– volume: 156
  start-page: 725
  issue: 4
  year: 2002
  end-page: 736
  ident: 131
  article-title: Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold
– volume: 11
  start-page: 6270
  issue: 17
  year: 2005
  end-page: 6279
  ident: 62
  article-title: Inhibition of integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy
– volume: 43
  start-page: 369
  issue: 5
  year: 1998
  end-page: 378
  ident: 193
  article-title: Cell migration strategies in 3-D extracellular matrix: differences in morphology, cell matrix interactions, and integrin function
– volume: 5
  issue: 1, article e8
  year: 2008
  ident: 187
  article-title: Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
– volume: 48
  start-page: 403
  issue: 4
  year: 2007
  end-page: 407
  ident: 32
  article-title: MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
– volume: 15
  start-page: 1309
  issue: 12
  year: 2009
  end-page: 1317
  ident: 49
  article-title: Cellular receptors of extracellular matrix molecules
– volume: 370
  start-page: 527
  issue: 6490
  year: 1994
  end-page: 532
  ident: 219
  article-title: Phosphatidylinositol-3-OH kinase as a direct target of Ras
– volume: 8
  start-page: 1484
  issue: 10
  year: 2009
  end-page: 1487
  ident: 102
  article-title: Rho-GTPase signaling drives melanoma cell plasticity
– volume: 23
  start-page: 7928
  issue: 48
  year: 2004
  end-page: 7946
  ident: 99
  article-title: The interplay between Src and integrins in normal and tumor biology
– volume: 108
  start-page: 3035
  issue: 9
  year: 2006
  end-page: 3044
  ident: 167
  article-title: Blockade of v 3 and v 5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells
– volume: 7
  start-page: 429
  issue: 6
  year: 2007
  end-page: 440
  ident: 204
  article-title: The cofilin pathway in breast cancer invasion and metastasis
– volume: 173
  start-page: 395
  issue: 3
  year: 2006
  end-page: 404
  ident: 207
  article-title: The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
– volume: 55
  start-page: 2752
  issue: 13
  year: 1995
  end-page: 2755
  ident: 78
  article-title: Overexpression of the focal adhesion kinase (p ) in invasive human tumors
– volume: 15
  start-page: 954
  issue: 2
  year: 1995
  end-page: 963
  ident: 80
  article-title: Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases
– volume: 3
  start-page: 307
  issue: 6
  year: 2005
  end-page: 315
  ident: 98
  article-title: Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of Src-transformed cells
– volume: 5
  start-page: 309
  issue: 2
  year: 1999
  end-page: 317
  ident: 235
  article-title: Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer
– volume: 11
  start-page: 747
  issue: 6
  year: 2009
  end-page: 756
  ident: 154
  article-title: Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro
– volume: 32
  start-page: 146
  issue: 2
  year: 2000
  end-page: 154
  ident: 205
  article-title: Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression
– volume: 278
  start-page: 46533
  issue: 47
  year: 2003
  end-page: 46540
  ident: 96
  article-title: Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells
– volume: 275
  start-page: 1943
  issue: 5308
  year: 1997
  end-page: 1947
  ident: 222
  article-title: PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
– volume: 10
  start-page: 1387
  issue: 21
  year: 2000
  end-page: 1390
  ident: 124
  article-title: The novel Rho-family GTPase Rif regulates coordinated actin-based membrane rearrangements
– volume: 25
  start-page: 1651
  issue: 13
  year: 2007
  end-page: 1657
  ident: 170
  article-title: Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma
– volume: 309
  start-page: 30
  issue: 5963
  year: 1984
  end-page: 33
  ident: 57
  article-title: Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
– volume: 140
  start-page: 961
  issue: 4
  year: 1998
  end-page: 972
  ident: 100
  article-title: CAS/Crk coupling serves as a “molecular switch” for induction of cell migration
– volume: 36
  start-page: 714
  issue: 5
  year: 1994
  end-page: 721
  ident: 30
  article-title: The retinoblastoma gene is involved in malignant progression of astrocytomas
– volume: 97
  start-page: 221
  issue: 2
  year: 1999
  end-page: 231
  ident: 116
  article-title: The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
– volume: 91
  start-page: 7727
  issue: 16
  year: 1994
  end-page: 7731
  ident: 16
  article-title: A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
– volume: 10
  start-page: 249
  issue: 2
  year: 2000
  end-page: 259
  ident: 36
  article-title: Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas
– volume: 3
  start-page: 523
  issue: 4
  year: 1997
  end-page: 530
  ident: 28
  article-title: Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies
– volume: 12
  start-page: 463
  year: 1996
  end-page: 519
  ident: 47
  article-title: Focal adhesions, contractility, and signaling
– volume: 40
  start-page: 151
  issue: 2
  year: 1998
  end-page: 160
  ident: 6
  article-title: Brain tumor survival: results from the national cancer data base
– volume: 66
  start-page: 159
  issue: 1
  year: 2006
  end-page: 167
  ident: 29
  article-title: Distinct transcription profiles of primary and secondary glioblastoma subgroups
– volume: 23
  start-page: 5294
  issue: 23
  year: 2005
  end-page: 5304
  ident: 188
  article-title: Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a north central cancer treatment group study
– volume: 13
  start-page: 1099
  issue: 23-24
  year: 2008
  end-page: 1106
  ident: 236
  article-title: The targeted delivery of cancer drugs across the blood-brain barrier: chemical modifications of drugs or drug-nanoparticles?
– volume: 27
  start-page: 86
  issue: 1
  year: 2008
  ident: 165
  article-title: Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/Src/AKT pathway
– volume: 57
  start-page: 1306
  issue: 12
  year: 2009
  end-page: 1315
  ident: 150
  article-title: Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis
– volume: 346
  start-page: 561
  issue: 3
  year: 2000
  end-page: 576
  ident: 221
  article-title: The PI3K-PBK1 connection: more than just a road to PKB
– volume: 108
  start-page: 224
  issue: 3
  year: 2004
  end-page: 230
  ident: 89
  article-title: Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas
– volume: 7
  start-page: 3420
  issue: 10
  year: 2008
  end-page: 3428
  ident: 230
  article-title: Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma
– volume: 377
  start-page: 539
  issue: 6549
  year: 1995
  end-page: 544
  ident: 75
  article-title: Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
– volume: 390
  start-page: 632
  issue: 6660
  year: 1997
  end-page: 636
  ident: 133
  article-title: Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
– volume: 46
  start-page: 488
  issue: 6
  year: 2007
  end-page: 496
  ident: 174
  article-title: A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth
– volume: 25
  start-page: 1470
  issue: 12
  year: 2007
  end-page: 1475
  ident: 33
  article-title: Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide
– volume: 22
  start-page: 1688
  issue: 11
  year: 2003
  end-page: 1702
  ident: 190
  article-title: integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells
– volume: 9
  start-page: 1046
  issue: 9
  year: 2007
  end-page: 1056
  ident: 121
  article-title: Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
– volume: 14
  start-page: 1002
  issue: 3
  year: 2003
  end-page: 1016
  ident: 199
  article-title: Specification of actin filament function and molecular composition by tropomyosin isoforms
– volume: 48
  start-page: 54
  issue: 1
  year: 2007
  end-page: 72
  ident: 88
  article-title: Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
– volume: 179
  start-page: 1043
  issue: 5
  year: 2007
  end-page: 1057
  ident: 107
  article-title: Vinculin controls focal adhesion formation by direct interactions with talin and actin
– volume: 140
  start-page: 211
  issue: 1
  year: 1998
  end-page: 221
  ident: 77
  article-title: Identification of p as a mediator of focal adhesion kinase-promoted cell migration
– volume: 114
  start-page: 97
  issue: 2
  year: 2007
  end-page: 109
  ident: 12
  article-title: The 2007 WHO classification of tumours of the central nervous system
– volume: 75
  start-page: 267
  issue: 3
  year: 2005
  end-page: 272
  ident: 35
  article-title: Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches
– volume: 54
  start-page: 6321
  issue: 24
  year: 1994
  end-page: 6324
  ident: 19
  article-title: CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
– volume: 70
  start-page: 217
  issue: 2
  year: 2004
  end-page: 228
  ident: 44
  article-title: Molecular mechanisms of glioma cell migration and invasion
– volume: 36
  start-page: 665
  issue: 6
  year: 2005
  end-page: 669
  ident: 64
  article-title: Integrin in central nervous system tumors
– volume: 10
  start-page: 111
  issue: 3
  year: 2000
  end-page: 119
  ident: 86
  article-title: Integrin signalling: a new Cas(t) of characters enters the stage
– volume: 3
  start-page: 489
  issue: 7
  year: 2003
  end-page: 501
  ident: 11
  article-title: Molecular mechanisms of glioma invasiveness: the role of proteases
– volume: 16
  start-page: 242
  issue: 3
  year: 2006
  end-page: 251
  ident: 117
  article-title: Purified integrin adhesion complexes exhibit actin-polymerization activity
– volume: 8
  start-page: 427
  issue: 4
  year: 2008
  end-page: 432
  ident: 92
  article-title: Src and focal adhesion kinase as therapeutic targets in cancer
– volume: 65
  start-page: 173
  year: 1999
  end-page: 205
  ident: 106
  article-title: Organization and polarity of actin filament networks in cells: implications for the mechanism of myosin-based cell motility
– volume: 135
  start-page: 510
  issue: 3
  year: 2008
  end-page: 523
  ident: 209
  article-title: Rac activation and inactivation control plasticity of tumor cell movement
– volume: 4
  start-page: 798
  issue: 9
  year: 1994
  end-page: 806
  ident: 218
  article-title: The activation of phosphatidylinositol 3-kinase by Ras
– volume: 111
  start-page: 1535
  issue: 11
  year: 1998
  end-page: 1544
  ident: 120
  article-title: Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin
– volume: 16
  start-page: 5623
  issue: 10
  year: 1996
  end-page: 5633
  ident: 81
  article-title: Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
– volume: 4
  start-page: 448
  issue: 4
  year: 2009
  end-page: 454
  ident: 183
  article-title: The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells
– volume: 168
  start-page: 619
  issue: 4
  year: 2005
  end-page: 631
  ident: 200
  article-title: Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin
– volume: 9
  start-page: 640
  issue: 12
  year: 1999
  end-page: 648
  ident: 128
  article-title: Interplay between Rac and Rho in the control of substrate contact dynamics
– volume: 95
  start-page: 151
  issue: 2
  year: 2009
  end-page: 163
  ident: 71
  article-title: Improving the prognosis for patients with glioblastoma: the rationale for targeting Src
– volume: 25
  start-page: 1637
  issue: 13
  year: 2007
  end-page: 1638
  ident: 171
  article-title: Integrin inhibitors reaching the clinic
– volume: 159
  start-page: 881
  issue: 5
  year: 2002
  end-page: 891
  ident: 118
  article-title: Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion
– volume: 2
  start-page: 143
  issue: 2
  year: 2007
  end-page: 158
  ident: 63
  article-title: Integrin v 3 antagonists for anti-angiogenic cancer treatment
– volume: 109
  start-page: 1787
  issue: 7
  year: 1996
  end-page: 1794
  ident: 76
  article-title: Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
– volume: 6
  start-page: 245
  issue: 3
  year: 2006
  end-page: 256
  ident: 203
  article-title: Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy
– volume: 129
  start-page: 1177
  issue: 6
  year: 2007
  end-page: 1187
  ident: 79
  article-title: Structural basis for the autoinhibition of focal adhesion kinase
– volume: 98
  start-page: 690
  issue: 5
  year: 2002
  end-page: 697
  ident: 168
  article-title: -integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin
– volume: 2
  start-page: 489
  issue: 7
  year: 2002
  end-page: 501
  ident: 217
  article-title: The phosphatidylinositol 3-kinase-AKT pathway in human cancer
– volume: 42
  start-page: 3033
  issue: 16
  year: 1999
  end-page: 3040
  ident: 163
  article-title: -methylated cyclic RGD peptides as highly active and selective integrin antagonists
– volume: 16
  start-page: 3169
  issue: 6
  year: 1996
  end-page: 3178
  ident: 84
  article-title: An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
– volume: 16
  start-page: 14
  issue: 1
  year: 2004
  end-page: 23
  ident: 41
  article-title: Prespecification and plasticity: shifting mechanisms of cell migration
– volume: 271
  start-page: 26329
  issue: 42
  year: 1996
  end-page: 26334
  ident: 83
  article-title: Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
– volume: 17
  start-page: 1225
  issue: 8
  year: 2008
  end-page: 1235
  ident: 164
  article-title: Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme
– volume: 88
  start-page: 1924
  issue: 6
  year: 1991
  end-page: 1932
  ident: 155
  article-title: Glioblastoma expression of vitronectin and the integrin. Adhesion mechanism for transformed glial cells
– volume: 14
  start-page: 305
  issue: 4
  year: 2003
  end-page: 312
  ident: 143
  article-title: Survival and prognostic factors of patients with unresectable glioblastoma multiforme
– volume: 2
  start-page: 595
  issue: 11
  year: 2004
  end-page: 605
  ident: 178
  article-title: Src regulates actin dynamics and invasion of malignant glial cells in three dimensions
– start-page: 1
  year: 2009
  end-page: 9
  ident: 175
  article-title: TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis
– volume: 6
  start-page: 154
  issue: 2
  year: 2004
  end-page: 161
  ident: 74
  article-title: FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
– volume: 359
  start-page: 492
  issue: 5
  year: 2008
  end-page: 507
  ident: 141
  article-title: Malignant gliomas in adults
– volume: 2
  start-page: 442
  issue: 6
  year: 2002
  end-page: 454
  ident: 215
  article-title: Epithelial-mesenchymal transitions in tumour progression
– volume: 146
  start-page: 1107
  issue: 5
  year: 1999
  end-page: 1116
  ident: 101
  article-title: Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
– volume: 75
  start-page: 819
  issue: 6
  year: 1996
  end-page: 826
  ident: 189
  article-title: Diffuse brain invasion of glioma cells requires beta 1 integrins
– volume: 9
  year: 2008
  ident: 239
  article-title: Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS
– volume: 372
  start-page: 786
  issue: 6508
  year: 1994
  end-page: 791
  ident: 105
  article-title: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
– volume: 92
  start-page: 9161
  issue: 20
  year: 1995
  end-page: 9165
  ident: 119
  article-title: Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion
– volume: 11
  start-page: 353
  issue: 8
  year: 2005
  end-page: 361
  ident: 184
  article-title: An expanding role for mTOR in cancer
– volume: 18
  start-page: 3831
  issue: 26
  year: 1999
  end-page: 3845
  ident: 125
  article-title: Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth
– volume: 98
  start-page: 1853
  issue: 4
  year: 2001
  end-page: 1858
  ident: 159
  article-title: Integrin activation controls metastasis in human breast cancer
– volume: 8
  start-page: 394
  issue: 2
  year: 2009
  end-page: 406
  ident: 180
  article-title: Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma
– volume: 29
  start-page: 877
  issue: 11
  year: 2005
  end-page: 883
  ident: 208
  article-title: Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin
– volume: 36
  start-page: 1046
  issue: 6
  year: 2004
  end-page: 1069
  ident: 9
  article-title: Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
– volume: 2
  start-page: 249
  issue: 5
  year: 2000
  end-page: 256
  ident: 22
  article-title: FAK integrates growth-factor and integrin signals to promote cell migration
– volume: 116
  start-page: 4409
  issue: 21
  year: 2003
  end-page: 4417
  ident: 212
  article-title: Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
– volume: 118
  start-page: 19
  issue: 1
  year: 2005
  end-page: 26
  ident: 135
  article-title: Cofilin takes the lead
– volume: 2
  start-page: 174
  issue: 3
  year: 2008
  end-page: 176
  ident: 132
  article-title: v-Crk regulates membrane dynamics and Rac activation
– volume: 131
  start-page: 989
  issue: 4
  year: 1995
  end-page: 1002
  ident: 109
  article-title: Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles
– issue: 4, article no. CD007415
  year: 2008
  ident: 147
  article-title: Temozolomide for high grade glioma
– volume: 8
  start-page: 918
  issue: 9
  year: 2002
  end-page: 921
  ident: 55
  article-title: A reevaluation of integrins as regulators of angiogenesis
– volume: 59
  start-page: 1304
  issue: 6
  year: 2006
  end-page: 1312
  ident: 166
  article-title: Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice
– volume: 69
  start-page: 6889
  issue: 17
  year: 2009
  end-page: 6898
  ident: 179
  article-title: Fyn and Src are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients
– volume: 57
  start-page: 4183
  issue: 19
  year: 1997
  end-page: 4186
  ident: 20
  article-title: Somatic mutations of PTEN in glioblastoma multiforme
– volume: 116
  start-page: 4605
  issue: 22
  year: 2003
  end-page: 4613
  ident: 60
  article-title: Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells
– volume: 62
  start-page: 2131
  issue: 7
  year: 2002
  end-page: 2140
  ident: 211
  article-title: Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes
– volume: 12
  start-page: 2723
  issue: 22
  year: 2006
  end-page: 2747
  ident: 56
  article-title: Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting
– volume: 290
  start-page: 333
  issue: 5490
  year: 2000
  end-page: 337
  ident: 129
  article-title: Localized Rac activation dynamics visualized in living cells
– volume: 18
  start-page: 35
  issue: 1
  year: 2008
  end-page: 44
  ident: 202
  article-title: Tropomyosins as interpreters of the signalling environment to regulate the local cytoskeleton
– volume: 83
  start-page: 588
  issue: 5
  year: 2000
  end-page: 593
  ident: 146
  article-title: A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
– volume: 56
  start-page: 180
  issue: 2
  year: 1997
  end-page: 185
  ident: 17
  article-title: Amplification and overexpression of MDM2 in primary (de novo) glioblastomas
– volume: 87
  start-page: 71
  issue: 1
  year: 2008
  end-page: 78
  ident: 229
  article-title: Variation of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
– volume: 15
  start-page: 2635
  issue: 5
  year: 1995
  end-page: 2645
  ident: 104
  article-title: pp -dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
– volume: 272
  start-page: 2446
  issue: 4
  year: 1997
  end-page: 2451
  ident: 195
  article-title: Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
– volume: 64
  start-page: 458
  issue: 4
  year: 2007
  end-page: 478
  ident: 1
  article-title: Molecular targets of glioma invasion
– volume: 155
  start-page: 1129
  issue: 7
  year: 2001
  end-page: 1135
  ident: 224
  article-title: The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
– volume: 53
  start-page: 11
  issue: 1
  year: 1994
  end-page: 21
  ident: 27
  article-title: The p53 gene and protein in human brain tumors
– volume: 59
  start-page: 141
  issue: 2
  year: 2004
  end-page: 152
  ident: 114
  article-title: Cellular localization of activated N-WASP using a conformation-sensitive antibody
– volume: 65
  start-page: 111
  year: 1999
  end-page: 123
  ident: 210
  article-title: Rho family proteins and cell migration
– volume: 29
  start-page: 1506
  issue: 6
  year: 2009
  end-page: 1514
  ident: 95
  article-title: Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction
– volume: 51
  start-page: 813
  issue: 5
  year: 1987
  end-page: 819
  ident: 48
  article-title: Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)
– volume: 26
  start-page: 145
  issue: 2
  year: 2008
  end-page: 151
  ident: 176
  article-title: TAE226 inhibits human neuroblastoma cell survival
– volume: 101
  start-page: 805
  issue: 4
  year: 2007
  end-page: 815
  ident: 42
  article-title: Tumor microenvironment: the role of the tumor stroma in cancer
– volume: 90
  start-page: 181
  issue: 2
  year: 2008
  end-page: 189
  ident: 91
  article-title: Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts
– volume: 98
  start-page: 10314
  issue: 18
  year: 2001
  end-page: 10319
  ident: 186
  article-title: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
– volume: 84
  start-page: 359
  issue: 3
  year: 1996
  end-page: 369
  ident: 45
  article-title: Cell migration: a physically integrated molecular process
– volume: 352
  start-page: 987
  issue: 10
  year: 2005
  end-page: 996
  ident: 4
  article-title: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
– volume: 62
  start-page: 4263
  issue: 15
  year: 2002
  end-page: 4272
  ident: 173
  article-title: Cilengitide targeting of integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts
– volume: 280
  start-page: 1614
  issue: 5369
  year: 1998
  end-page: 1617
  ident: 23
  article-title: Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
– volume: 60
  start-page: 1383
  issue: 5
  year: 2000
  end-page: 1387
  ident: 15
  article-title: Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
– volume: 9
  start-page: 126
  issue: 2
  year: 2003
  end-page: 133
  ident: 69
  article-title: FAK signaling in anaplastic astrocytoma and glioblastoma tumors
– volume: 106
  start-page: 10666
  issue: 26
  year: 2009
  end-page: 10671
  ident: 191
  article-title: Activation of tumor cell integrin alphavbeta3 controls angiogenesis and metastatic growth in the brain
– volume: 22
  start-page: 1715
  issue: 10
  year: 2001
  end-page: 1719
  ident: 31
  article-title: Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C → A:T mutations of the TP53 tumor suppressor gene
– volume: 19
  start-page: 1318
  issue: 10
  year: 2000
  end-page: 1328
  ident: 90
  article-title: RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion
– volume: 4
  start-page: 2625
  issue: 11
  year: 1998
  end-page: 2634
  ident: 160
  article-title: Vascular integrin : a new prognostic indicator in breast cancer
– volume: 6
  start-page: 705
  issue: 7
  year: 2009
  end-page: 718
  ident: 234
  article-title: Targeted drug delivery for treatment and imaging of glioblastoma multiforme
– volume: 170
  start-page: 1445
  issue: 5
  year: 2007
  end-page: 1453
  ident: 13
  article-title: Genetic pathways to primary and secondary glioblastoma
– volume: 25
  start-page: 1721
  issue: 12
  year: 2006
  end-page: 1732
  ident: 70
  article-title: HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
– volume: 81
  start-page: 53
  issue: 1
  year: 1995
  end-page: 62
  ident: 115
  article-title: Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
– volume: 84
  start-page: 610
  year: 1960
  end-page: 628
  ident: 140
  article-title: Radiation therapy in the management of neoplasms of the central nervous system, with a special note in regard to children: twenty years experience
– volume: 14
  start-page: 7330
  issue: 22
  year: 2008
  end-page: 7339
  ident: 67
  article-title: Integrin -targeted radioimmunotherapy of glioblastoma multiforme
– volume: 60
  start-page: 196
  issue: 2
  year: 2008
  end-page: 209
  ident: 233
  article-title: Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy
– volume: 19
  start-page: 3357
  issue: 8
  year: 2008
  end-page: 3368
  ident: 38
  article-title: The role of myosin II in glioma invasion of the brain
– volume: 122
  start-page: 3037
  issue: 17
  year: 2009
  end-page: 3049
  ident: 112
  article-title: Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions
– volume: 55
  start-page: 1143
  issue: 11
  year: 1996
  end-page: 1149
  ident: 59
  article-title: Expression of integrin in small blood vessels of glioblastoma tumors
– volume: 3
  start-page: 6
  issue: 1
  year: 2000
  end-page: 12
  ident: 54
  article-title: Cell adhesion and chemotaxis in prostate cancer metastasis to bone: a minireview
– volume: 134
  start-page: 793
  issue: 3
  year: 1996
  end-page: 799
  ident: 157
  article-title: Control of adhesion-dependent cell survival by focal adhesion kinase
– volume: 2
  start-page: 91
  issue: 2
  year: 2002
  end-page: 100
  ident: 51
  article-title: Role of integrins in cell invasion and migration
– volume: 3
  start-page: 248
  issue: 3
  year: 2009
  end-page: 261
  ident: 182
  article-title: Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530
– volume: 54
  start-page: 236
  issue: 2
  year: 1995
  end-page: 244
  ident: 192
  article-title: Effects of transforming growth factor- 1 on collagen synthesis, integrin expression, adhesion and invasion of glioma cells
– volume: 20
  start-page: 203
  issue: 3
  year: 2003
  end-page: 213
  ident: 52
  article-title: Integrin adhesion receptors in tumor metastasis
– volume: 177
  start-page: 515
  issue: 3
  year: 2007
  end-page: 525
  ident: 61
  article-title: v 3 and 5 1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration
– volume: 9
  start-page: 858
  issue: 8
  year: 2007
  end-page: 867
  ident: 72
  article-title: Functional atlas of the integrin adhesome
– volume: 15
  start-page: 297
  issue: 4
  year: 2005
  end-page: 310
  ident: 148
  article-title: Angiogenesis in gliomas: biology and molecular pathophysiology
– volume: 60
  start-page: 153
  issue: 3
  year: 2005
  end-page: 165
  ident: 206
  article-title: The motility of glioblastoma tumour cells is modulated by intracellular cofilin expression in a concentration-dependent manner
– volume: 270
  start-page: 17437
  issue: 29
  year: 1995
  end-page: 17441
  ident: 103
  article-title: Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase
– volume: 6
  start-page: 1017
  issue: 10
  year: 2009
  end-page: 1032
  ident: 238
  article-title: New strategies to deliver anticancer drugs to brain tumors
– volume: 38
  start-page: 755
  issue: 4
  year: 1996
  end-page: 764
  ident: 43
  article-title: Migration of human glioma cells on myelin
– volume: 64
  start-page: 1197
  issue: 4
  year: 2006
  end-page: 1203
  ident: 181
  article-title: Src family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation
– volume: 9
  start-page: 519
  issue: 4
  year: 2009
  end-page: 534
  ident: 198
  article-title: Therapeutic strategies for inhibiting invasion in glioblastoma
– volume: 84
  start-page: 6899
  issue: 19
  year: 1987
  end-page: 6903
  ident: 21
  article-title: Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
– volume: 18
  start-page: 26
  issue: 1
  year: 2006
  end-page: 31
  ident: 136
  article-title: Cofilin phosphatases and regulation of actin dynamics
– volume: 66
  start-page: 405
  issue: 5
  year: 2007
  end-page: 417
  ident: 228
  article-title: IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients
– volume: 23
  start-page: 138
  issue: 2
  year: 2005
  end-page: 144
  ident: 145
  article-title: Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life
– volume: 27
  start-page: 4998
  issue: 37
  year: 2008
  end-page: 5010
  ident: 185
  article-title: Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins
– volume: 41
  start-page: 341
  issue: 2
  year: 2009
  end-page: 348
  ident: 50
  article-title: Evolution of collagen-based adhesion systems
– volume: 26
  start-page: 4191
  issue: 6B
  year: 2006
  end-page: 4194
  ident: 18
  article-title: Uniform MDM2 overexpression in a panel of glioblastoma multiforme cell lines with divergent EGFR and p53 expression status
– volume: 59
  start-page: 241
  issue: 1
  year: 1999
  end-page: 248
  ident: 53
  article-title: Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for human micrometastases
– volume: 16
  start-page: 522
  issue: 10
  year: 2006
  end-page: 529
  ident: 113
  article-title: Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
– volume: 15
  start-page: 356
  issue: 4
  year: 1997
  end-page: 362
  ident: 223
  article-title: Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
– volume: 42
  start-page: 969
  issue: 7
  year: 2009
  end-page: 980
  ident: 58
  article-title: Ligands for mapping -integrin expression in vivo
– volume: 9
  start-page: 519
  issue: 4
  year: 2009
  end-page: 534
  ident: 153
  article-title: Therapeutic strategies for inhibiting invasion in glioblastoma
– volume: 21
  start-page: 2683
  issue: 21
  year: 2007
  end-page: 2710
  ident: 2
  article-title: Malignant astrocytic glioma: genetics, biology, and paths to treatment
– volume: 101
  start-page: 7618
  issue: 20
  year: 2004
  end-page: 7623
  ident: 216
  article-title: Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
– volume: 6
  start-page: 2505
  issue: 9
  year: 2007
  end-page: 2514
  ident: 226
  article-title: The phosphatidylinositol 3-kinase inhibitor, PX-866, is a potent inhibitor of cancer cell motility and growth in three-dimensional cultures
– volume: 123
  start-page: 2676
  issue: 11
  year: 2008
  end-page: 2683
  ident: 231
  article-title: Original triazine inductor of new specific molecular targets, with antitumor activity against nonsmall cell lung cancer
– volume: 407
  start-page: 249
  issue: 6801
  year: 2000
  end-page: 257
  ident: 161
  article-title: Angiogenesis in cancer and other diseases
– volume: 33
  start-page: 49
  issue: 1
  year: 2000
  end-page: 55
  ident: 68
  article-title: Molecular events implicated in brain tumor angiogenesis and invasion
– volume: 26
  start-page: 239
  issue: 2
  year: 1993
  end-page: 244
  ident: 142
  article-title: Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials
– volume: 17
  start-page: 81
  issue: 1
  year: 1998
  end-page: 92
  ident: 93
  article-title: The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
– volume: 4
  start-page: 718
  issue: 9
  year: 1954
  end-page: 721
  ident: 139
  article-title: Total left cerebral hemispherectomy for malignant glioma
– volume: 352
  start-page: 997
  issue: 10
  year: 2005
  end-page: 1003
  ident: 34
  article-title: MGMT gene silencing and benefit from temozolomide in glioblastoma
– volume: 166
  start-page: 697
  issue: 5
  year: 2004
  end-page: 708
  ident: 137
  article-title: Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
– volume: 59
  start-page: 442
  issue: 2
  year: 1999
  end-page: 449
  ident: 24
  article-title: Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas
– volume: 277
  start-page: 567
  issue: 5325
  year: 1997
  end-page: 570
  ident: 220
  article-title: Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
– volume: 10
  start-page: 401
  issue: 7
  year: 2000
  end-page: 404
  ident: 225
  article-title: Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
– volume: 20
  start-page: E5
  issue: 4
  year: 2006
  ident: 3
  article-title: Recurrent glioblastoma multiforme: a review of natural history and management options
– volume: 21
  start-page: 7641
  issue: 22
  year: 2001
  end-page: 7652
  ident: 87
  article-title: Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src
– volume: 105
  start-page: 739
  issue: 5
  year: 2006
  end-page: 744
  ident: 8
  article-title: Genetic profiling of a distant second glioblastoma multiforme after radiotherapy: recurrence or second primary tumor?
– volume: 17
  start-page: 6906
  issue: 12
  year: 1997
  end-page: 6914
  ident: 85
  article-title: Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation
– volume: 153
  start-page: 569
  issue: 3
  year: 2001
  end-page: 584
  ident: 108
  article-title: Rho-kinase—mediated contraction of isolated stress fibers
– start-page: 69
  issue: 4
  year: 1989
  end-page: 75
  ident: 214
  article-title: Reversible transition towards a fibroblastic phenotype in a rat carcinoma cell line
– volume: 18
  start-page: 2435
  issue: 4A
  year: 1998
  end-page: 2447
  ident: 10
  article-title: Glioma cell adhesion and migration on human brain sections
– volume: 28
  start-page: 1570
  issue: 13
  year: 2009
  end-page: 1583
  ident: 134
  article-title: Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
– volume: 26
  start-page: 5610
  issue: 34
  year: 2008
  end-page: 5617
  ident: 169
  article-title: Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
– volume: 11
  start-page: 160
  issue: 1
  year: 2010
  end-page: 167
  ident: 197
  article-title: Two-step synthesis of multivalent cancer-targeting constructs
– volume: 101
  start-page: 570
  issue: 6
  year: 2007
  end-page: 580
  ident: 65
  article-title: Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis
– volume: 11
  start-page: 6767
  issue: 19, part 1
  year: 2005
  end-page: 6771
  ident: 144
  article-title: Food and drug administration drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme
– volume: 3
  start-page: 355
  issue: 4
  year: 2009
  end-page: 357
  ident: 201
  article-title: The coordination between actin filaments and adhesion in mesenchymal migration
– volume: 114
  start-page: 2713
  issue: 15
  year: 2001
  end-page: 2722
  ident: 130
  article-title: Rho GTPases and cell migration
– volume: 70
  start-page: 779
  issue: 10
  year: 2008
  end-page: 787
  ident: 152
  article-title: Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence
– volume: 120
  start-page: 137
  issue: 1
  year: 2007
  end-page: 148
  ident: 94
  article-title: A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions
– volume: 279
  start-page: 38331
  issue: 37
  year: 2004
  end-page: 38337
  ident: 97
  article-title: Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration
– volume: 67
  start-page: 10976
  issue: 22
  year: 2007
  end-page: 10983
  ident: 177
  article-title: Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma
– volume: 1
  start-page: 44
  issue: 1
  year: 1999
  end-page: 51
  ident: 14
  article-title: Primary and secondary glioblastomas: from concept to clinical diagnosis
– volume: 18
  start-page: 2571
  issue: 5
  year: 1998
  end-page: 2585
  ident: 82
  article-title: Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events?
– volume: 112
  start-page: 2677
  issue: 16
  year: 1999
  end-page: 2691
  ident: 73
  article-title: Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
– volume: 49
  start-page: 380
  issue: 2
  year: 2001
  end-page: 390
  ident: 156
  article-title: and integrin expression in glioma periphery
– volume: 6
  start-page: 449
  issue: 6
  year: 2006
  end-page: 458
  ident: 213
  article-title: Metastasis: a question of life or death
– volume: 346
  start-page: 420
  issue: 6
  year: 2002
  end-page: 427
  ident: 37
  article-title: Expression of p53 and prognosis in children with malignant gliomas
– volume: 302
  start-page: 1704
  issue: 5651
  year: 2003
  end-page: 1709
  ident: 126
  article-title: Cell Migration: integrating signals from front to back
– volume: 15
  start-page: 1311
  issue: 11
  year: 2001
  end-page: 1333
  ident: 25
  article-title: Malignant glioma: genetics and biology of a grave matter
– volume: 48
  start-page: 5546
  issue: 19
  year: 1988
  end-page: 5551
  ident: 26
  article-title: Clonal genomic alterations in glioma malignancy stages
– volume: 276
  start-page: 4527
  issue: 7
  year: 2001
  end-page: 4530
  ident: 110
  article-title: Dedicated myosin light chain kinases with diverse cellular functions
– start-page: 277
  issue: 70
  year: 2003
  end-page: 285
  ident: 196
  article-title: Proteolytic and non-proteolytic migration of tumour cells and leucocytes
– volume: 70
  start-page: 389
  issue: 3
  year: 1992
  end-page: 399
  ident: 127
  article-title: The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
– volume: 18
  start-page: 1400
  issue: 8
  year: 2007
  end-page: 1407
  ident: 172
  article-title: Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors
– volume: 3
  start-page: 362
  issue: 5
  year: 2003
  end-page: 374
  ident: 40
  article-title: Tumour-cell invasion and migration: diversity and escape mechanisms
– volume: 153
  start-page: 1427
  issue: 7
  year: 2001
  end-page: 1440
  ident: 46
  article-title: Differential dynamics of 5 integrin, paxillin, and -actinin during formation and disassembly of adhesions in migrating cells
– volume: 61
  start-page: 6624
  issue: 18
  year: 2001
  end-page: 6628
  ident: 149
  article-title: Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
– volume: 2
  start-page: 105
  issue: 2
  year: 2006
  end-page: 114
  ident: 39
  article-title: Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration
– volume: 167
  start-page: 1379
  issue: 5
  year: 2005
  end-page: 1387
  ident: 66
  article-title: In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation
– volume: 144
  start-page: 1235
  issue: 6
  year: 1999
  end-page: 1244
  ident: 122
  article-title: Rho GTPases control polarity, protrusion, and adhesion during cell movement
– volume: 2
  start-page: 306
  issue: 4
  year: 2000
  end-page: 314
  ident: 151
  article-title: Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
– volume: 43
  start-page: 79
  issue: 1
  year: 1999
  end-page: 88
  ident: 7
  article-title: Patterns of failure following high-dose 3-D conformal radiotherapy for high-grade astrocytomas: a quantitative dosimetric study
– volume: 13
  start-page: 113
  issue: 2
  year: 2006
  end-page: 135
  ident: 158
  article-title: Vascular integrins in tumor angiogenesis: mediators and therapeutic targets
– volume: 6
  start-page: 539
  issue: 3
  year: 2009
  end-page: 546
  ident: 237
  article-title: Novel drug delivery strategies in neuro-oncology
– volume: 274
  start-page: 24947
  issue: 35
  year: 1999
  end-page: 24952
  ident: 194
  article-title: A novel protease-docking function of integrin at invadopodia
– volume: 270
  start-page: 1500
  issue: 5241
  year: 1995
  end-page: 1502
  ident: 162
  article-title: Definition of two angiogenic pathways by distinct alpha v integrins
– ident: 154
  doi: 10.1215/15228517-2009-012
– volume: 3
  start-page: 489
  issue: 7
  year: 2003
  ident: 11
  publication-title: Nature Reviews Cancer
  doi: 10.1038/nrc1121
– ident: 137
  doi: 10.1083/jcb.200405156
– ident: 134
  doi: 10.1038/onc.2009.2
– volume: 20
  start-page: E5
  issue: 4
  year: 2006
  ident: 3
  publication-title: Neurosurgical Focus
– volume: 53
  start-page: 11
  issue: 1
  year: 1994
  ident: 27
  publication-title: Journal of Neuropathology and Experimental Neurology
  doi: 10.1097/00005072-199401000-00002
– ident: 12
  doi: 10.1007/s00401-007-0243-4
– volume: 270
  start-page: 1500
  issue: 5241
  year: 1995
  ident: 162
  publication-title: Science
  doi: 10.1126/science.270.5241.1500
– ident: 131
  doi: 10.1083/jcb.200111032
– ident: 174
  doi: 10.1002/mc.20297
– ident: 163
  doi: 10.1021/jm970832g
– ident: 98
  doi: 10.1158/1541-7786.MCR-05-0015
– ident: 74
  doi: 10.1038/ncb1094
– ident: 40
  doi: 10.1038/nrc1075
– volume: 167
  start-page: 1379
  issue: 5
  year: 2005
  ident: 66
  publication-title: American Journal of Pathology
  doi: 10.1016/S0002-9440(10)61225-4
– ident: 97
  doi: 10.1074/jbc.M404675200
– ident: 195
  doi: 10.1074/jbc.272.4.2446
– ident: 218
  doi: 10.1016/S0960-9822(00)00177-9
– ident: 236
  doi: 10.1016/j.drudis.2008.09.005
– ident: 166
  doi: 10.1227/01.NEU.0000245622.70344.BE
– ident: 194
  doi: 10.1074/jbc.274.35.24947
– volume: 16
  start-page: 5623
  issue: 10
  year: 1996
  ident: 81
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.16.10.5623
– ident: 39
  doi: 10.1017/S1740925X06000111
– ident: 153
  doi: 10.1586/ern.09.10
– ident: 4
  doi: 10.1056/NEJMoa043330
– ident: 1
  doi: 10.1007/s00018-007-6342-5
– volume: 15
  start-page: 297
  issue: 4
  year: 2005
  ident: 148
  publication-title: Brain Pathology
  doi: 10.1111/j.1750-3639.2005.tb00115.x
– volume: 377
  start-page: 539
  issue: 6549
  year: 1995
  ident: 75
  publication-title: Nature
  doi: 10.1038/377539a0
– ident: 216
  doi: 10.1073/pnas.0307512101
– ident: 238
  doi: 10.1517/17425240903167942
– ident: 7
  doi: 10.1016/S0360-3016(98)00266-1
– ident: 49
  doi: 10.2174/138161209787846720
– volume: 18
  start-page: 2435
  issue: 4a
  year: 1998
  ident: 10
  publication-title: Anticancer Research
– volume: 2
  start-page: 143
  issue: 2
  year: 2007
  ident: 63
  publication-title: Recent Patents on Anti-Cancer Drug Discovery
  doi: 10.2174/157489207780832469
– ident: 87
  doi: 10.1128/MCB.21.22.7641-7652.2001
– ident: 113
  doi: 10.1016/j.tcb.2006.08.006
– ident: 136
  doi: 10.1016/j.ceb.2005.11.005
– ident: 193
  doi: 10.1002/(SICI)1097-0029(19981201)43:5<369::AID-JEMT3>3.0.CO;2-6
– ident: 185
  doi: 10.1038/onc.2008.137
– ident: 208
  doi: 10.1016/j.cellbi.2005.07.005
– ident: 207
  doi: 10.1083/jcb.200510115
– volume: 18
  start-page: 2571
  issue: 5
  year: 1998
  ident: 82
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.18.5.2571
– volume: 112
  start-page: 2677
  issue: 16
  year: 1999
  ident: 73
  publication-title: Journal of Cell Science
  doi: 10.1242/jcs.112.16.2677
– ident: 150
  doi: 10.1002/glia.20850
– volume: 2
  start-page: 174
  issue: 3
  year: 2008
  ident: 132
  publication-title: Cell Adhesion & Migration
  doi: 10.4161/cam.2.3.6578
– volume: 51
  start-page: 813
  issue: 5
  year: 1987
  ident: 48
  publication-title: Cell
  doi: 10.1016/0092-8674(87)90104-8
– volume: 109
  start-page: 1787
  issue: 7
  year: 1996
  ident: 76
  publication-title: Journal of Cell Science
  doi: 10.1242/jcs.109.7.1787
– ident: 95
  doi: 10.1128/MCB.00857-08
– start-page: 277
  issue: 70
  year: 2003
  ident: 196
  publication-title: Biochemical Society Symposium
– ident: 204
  doi: 10.1038/nrc2148
– ident: 46
  doi: 10.1083/jcb.153.7.1427
– ident: 191
  doi: 10.1073/pnas.0903035106
– ident: 55
  doi: 10.1038/nm0902-918
– volume: 84
  start-page: 610
  year: 1960
  ident: 140
  publication-title: American Journal of Roentgenology
– ident: 45
  doi: 10.1016/S0092-8674(00)81280-5
– ident: 94
  doi: 10.1242/jcs.03314
– ident: 234
  doi: 10.1517/17425240902988470
– volume: 14
  start-page: 7330
  issue: 22
  year: 2008
  ident: 67
  publication-title: Clinical Cancer Research
  doi: 10.1158/1078-0432.CCR-08-0797
– volume: 81
  start-page: 53
  issue: 1
  year: 1995
  ident: 115
  publication-title: Cell
  doi: 10.1016/0092-8674(95)90370-4
– ident: 103
  doi: 10.1074/jbc.270.29.17437
– ident: 202
  doi: 10.1016/j.semcancer.2007.08.004
– ident: 176
  doi: 10.1080/07357900701577475
– volume: 3
  start-page: 523
  issue: 4
  year: 1997
  ident: 28
  publication-title: Clinical Cancer Research
– ident: 69
  doi: 10.1097/00130404-200303000-00008
– ident: 177
  doi: 10.1158/0008-5472.CAN-07-2667
– volume: 62
  start-page: 4263
  issue: 15
  year: 2002
  ident: 173
  publication-title: Cancer Research
– ident: 182
  doi: 10.1016/j.molonc.2009.01.002
– ident: 72
  doi: 10.1038/ncb0807-858
– volume: 55
  start-page: 1143
  issue: 11
  year: 1996
  ident: 59
  publication-title: Journal of Neuropathology and Experimental Neurology
  doi: 10.1097/00005072-199611000-00005
– ident: 143
  doi: 10.1097/00001813-200304000-00008
– ident: 101
  doi: 10.1083/jcb.146.5.1107
– ident: 181
  doi: 10.1016/j.ijrobp.2005.11.014
– ident: 41
  doi: 10.1016/j.ceb.2003.11.001
– volume: 26
  start-page: 239
  issue: 2
  year: 1993
  ident: 142
  publication-title: International Journal of Radiation Oncology Biology Physics
  doi: 10.1016/0360-3016(93)90203-8
– ident: 152
  doi: 10.1212/01.wnl.0000304121.57857.38
– ident: 22
  doi: 10.1038/35010517
– ident: 197
  doi: 10.1021/bm9010276
– ident: 25
  doi: 10.1101/gad.891601
– ident: 133
  doi: 10.1038/37656
– volume: 2
  start-page: 595
  issue: 11
  year: 2004
  ident: 178
  publication-title: Molecular Cancer Research
  doi: 10.1158/1541-7786.595.2.11
– ident: 44
  doi: 10.1007/s11060-004-2751-6
– volume: 3
  start-page: 6
  issue: 1
  year: 2000
  ident: 54
  publication-title: Prostate Cancer and Prostatic Diseases
  doi: 10.1038/sj.pcan.4500387
– ident: 200
  doi: 10.1083/jcb.200406063
– ident: 61
  doi: 10.1083/jcb.200609004
– ident: 33
  doi: 10.1200/JCO.2006.07.4807
– ident: 88
  doi: 10.1007/s12013-007-0036-3
– ident: 124
  doi: 10.1016/S0960-9822(00)00777-6
– ident: 205
  doi: 10.1002/1098-1136(200011)32:2<146::AID-GLIA40>3.0.CO;2-3
– ident: 213
  doi: 10.1038/nrc1886
– volume: 59
  start-page: 241
  issue: 1
  year: 1999
  ident: 53
  publication-title: Cancer Research
– ident: 232
  doi: 10.1146/annurev.pharmtox.47.120505.105237
– ident: 37
  doi: 10.1056/NEJMoa012224
– ident: 100
  doi: 10.1083/jcb.140.4.961
– ident: 112
  doi: 10.1242/jcs.052704
– ident: 158
  doi: 10.1080/10623320600698037
– ident: 190
  doi: 10.1038/sj.onc.1206347
– ident: 30
  doi: 10.1002/ana.410360505
– volume: 15
  start-page: 954
  issue: 2
  year: 1995
  ident: 80
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.15.2.954
– ident: 123
  doi: 10.1042/BJ20031041
– ident: 8
  doi: 10.3171/jns.2006.105.5.739
– ident: 231
  doi: 10.1002/ijc.23809
– ident: 119
  doi: 10.1073/pnas.92.20.9161
– ident: 220
  doi: 10.1126/science.277.5325.567
– ident: 228
  doi: 10.1097/nen.0b013e31804567d7
– ident: 111
  doi: 10.1016/S0165-6147(00)01596-0
– ident: 156
  doi: 10.1097/00006123-200108000-00022
– ident: 184
  doi: 10.1016/j.molmed.2005.06.007
– volume: 88
  start-page: 1924
  issue: 6
  year: 1991
  ident: 155
  publication-title: Journal of Clinical Investigation
  doi: 10.1172/JCI115516
– ident: 127
  doi: 10.1016/0092-8674(92)90163-7
– volume: 108
  start-page: 3035
  issue: 9
  year: 2006
  ident: 167
  publication-title: Blood
  doi: 10.1182/blood-2006-05-023580
– volume: 65
  start-page: 111
  year: 1999
  ident: 210
  publication-title: Biochemical Society Symposium
– ident: 83
  doi: 10.1074/jbc.271.42.26329
– ident: 35
  doi: 10.1007/s11060-005-6749-5
– ident: 56
  doi: 10.2174/138161206777947740
– ident: 222
  doi: 10.1126/science.275.5308.1943
– start-page: 69
  issue: 4
  year: 1989
  ident: 214
  publication-title: International Journal of Cancer
– volume: 114
  start-page: 2713
  issue: 15
  year: 2001
  ident: 130
  publication-title: Journal of Cell Science
  doi: 10.1242/jcs.114.15.2713
– volume: 2
  start-page: 489
  issue: 7
  year: 2002
  ident: 217
  publication-title: Nature Reviews Cancer
  doi: 10.1038/nrc839
– ident: 6
  doi: 10.1023/A:1006091608586
– volume: 4
  start-page: 2625
  issue: 11
  year: 1998
  ident: 160
  publication-title: Clinical Cancer Research
– ident: 129
  doi: 10.1126/science.290.5490.333
– ident: 34
  doi: 10.1056/NEJMoa043331
– ident: 141
  doi: 10.1056/NEJMra0708126
– ident: 199
  doi: 10.1091/mbc.E02-04-0244
– ident: 99
  doi: 10.1038/sj.onc.1208080
– ident: 169
  doi: 10.1200/JCO.2008.16.7510
– ident: 117
  doi: 10.1016/j.cub.2005.12.033
– ident: 52
  doi: 10.1023/A:1022983000355
– ident: 225
  doi: 10.1016/S0960-9822(00)00417-6
– volume: 8
  start-page: 1484
  issue: 10
  year: 2009
  ident: 102
  publication-title: Cell Cycle
  doi: 10.4161/cc.8.10.8490
– volume: 15
  start-page: 2635
  issue: 5
  year: 1995
  ident: 104
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.15.5.2635
– ident: 50
  doi: 10.1016/j.biocel.2008.08.021
– ident: 65
  doi: 10.1161/CIRCRESAHA.107.155655
– ident: 175
  doi: 10.1007/s10637-009-9326-5
– volume: 134
  start-page: 793
  issue: 3
  year: 1996
  ident: 157
  publication-title: The Journal of Cell Biology
  doi: 10.1083/jcb.134.3.793
– volume: 84
  start-page: 6899
  issue: 19
  year: 1987
  ident: 21
  publication-title: Proceedings of the National Academy of Sciences of the United States of America
  doi: 10.1073/pnas.84.19.6899
– volume: 17
  start-page: 6906
  issue: 12
  year: 1997
  ident: 85
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.17.12.6906
– volume: 62
  start-page: 2131
  issue: 7
  year: 2002
  ident: 211
  publication-title: Cancer Research
– ident: 77
  doi: 10.1083/jcb.140.1.211
– ident: 165
  doi: 10.1186/1756-9966-27-86
– ident: 171
  doi: 10.1200/JCO.2006.09.8376
– volume: 56
  start-page: 180
  issue: 2
  year: 1997
  ident: 17
  publication-title: Journal of Neuropathology and Experimental Neurology
  doi: 10.1097/00005072-199702000-00009
– ident: 183
  doi: 10.1097/JTO.0b013e31819c78fb
– volume: 16
  start-page: 3169
  issue: 6
  year: 1996
  ident: 84
  publication-title: Molecular and Cellular Biology
  doi: 10.1128/MCB.16.6.3169
– volume: 83
  start-page: 588
  issue: 5
  year: 2000
  ident: 146
  publication-title: British Journal of Cancer
  doi: 10.1054/bjoc.2000.1316
– ident: 23
  doi: 10.1126/science.280.5369.1614
– volume: 33
  start-page: 49
  issue: 1
  year: 2000
  ident: 68
  publication-title: Pediatric Neurosurgery
  doi: 10.1159/000028975
– ident: 16
  doi: 10.1073/pnas.91.16.7727
– ident: 79
  doi: 10.1016/j.cell.2007.05.041
– volume: 65
  start-page: 173
  year: 1999
  ident: 106
  publication-title: Biochemical Society Symposium
– volume: 59
  start-page: 442
  issue: 2
  year: 1999
  ident: 24
  publication-title: Cancer Research
– ident: 219
  doi: 10.1038/370527a0
– ident: 122
  doi: 10.1083/jcb.144.6.1235
– ident: 229
  doi: 10.1007/s11060-007-9486-0
– ident: 29
  doi: 10.1158/0008-5472.CAN-05-0077
– volume: 309
  start-page: 30
  issue: 5963
  year: 1984
  ident: 57
  publication-title: Nature
  doi: 10.1038/309030a0
– ident: 38
  doi: 10.1091/mbc.E08-03-0319
– ident: 223
  doi: 10.1038/ng0497-356
– ident: 226
  doi: 10.1158/1535-7163.MCT-06-0698
– volume: 3
  start-page: 355
  issue: 4
  year: 2009
  ident: 201
  publication-title: Cell Adhesion and Migration
  doi: 10.4161/cam.3.4.9468
– volume: 26
  start-page: 4191
  issue: 6b
  year: 2006
  ident: 18
  publication-title: Anticancer Research
– ident: 13
  doi: 10.2353/ajpath.2007.070011
– ident: 70
  doi: 10.1038/sj.onc.1209199
– ident: 107
  doi: 10.1083/jcb.200703036
– ident: 62
  doi: 10.1158/1078-0432.CCR-04-1223
– ident: 71
  doi: 10.1007/s11060-009-9916-2
– ident: 86
  doi: 10.1016/S0962-8924(99)01714-6
– ident: 179
  doi: 10.1158/0008-5472.CAN-09-0347
– ident: 233
  doi: 10.1124/pr.107.07109
– ident: 159
  doi: 10.1073/pnas.98.4.1853
– ident: 227
  doi: 10.1038/ncb1762
– volume: 10
  start-page: 249
  issue: 2
  year: 2000
  ident: 36
  publication-title: Brain Pathology
  doi: 10.1111/j.1750-3639.2000.tb00258.x
– ident: 58
  doi: 10.1021/ar800243b
– ident: 144
  doi: 10.1158/1078-0432.CCR-05-0722
– ident: 93
  doi: 10.1093/emboj/17.1.81
– ident: 121
  doi: 10.1038/ncb1626
– ident: 92
  doi: 10.1016/j.coph.2008.06.012
– volume: 5
  start-page: 309
  issue: 2
  year: 1999
  ident: 235
  publication-title: Clinical Cancer Research
– ident: 147
  doi: 10.1002/14651858.CD007415
– ident: 42
  doi: 10.1002/jcb.21159
– ident: 64
  doi: 10.1016/j.humpath.2005.03.014
– ident: 172
  doi: 10.1093/annonc/mdm140
– ident: 170
  doi: 10.1200/JCO.2006.06.6514
– ident: 188
  doi: 10.1200/JCO.2005.23.622
– ident: 198
  doi: 10.1586/ern.09.10
– start-page: 3
  volume-title: Historical perspective
  year: 1995
  ident: 138
– ident: 209
  doi: 10.1016/j.cell.2008.09.043
– ident: 212
  doi: 10.1242/jcs.00712
– volume: 111
  start-page: 1535
  issue: 11
  year: 1998
  ident: 120
  publication-title: Journal of Cell Science
  doi: 10.1242/jcs.111.11.1535
– ident: 237
  doi: 10.1016/j.nurt.2009.04.004
– ident: 96
  doi: 10.1074/jbc.M307526200
– volume: 54
  start-page: 6321
  issue: 24
  year: 1994
  ident: 19
  publication-title: Cancer Research
– volume: 75
  start-page: 819
  issue: 6
  year: 1996
  ident: 189
  publication-title: Laboratory Investigation
– ident: 109
  doi: 10.1083/jcb.131.4.989
– ident: 168
  doi: 10.1002/ijc.10265
– ident: 9
  doi: 10.1016/j.biocel.2004.01.013
– volume: 19
  start-page: 1318
  issue: 10
  year: 2000
  ident: 90
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1203422
– volume: 4
  start-page: 718
  issue: 9
  year: 1954
  ident: 139
  publication-title: Neurology
  doi: 10.1212/WNL.4.9.718
– volume: 48
  start-page: 5546
  issue: 19
  year: 1988
  ident: 26
  publication-title: Cancer Research
– ident: 125
  doi: 10.1038/sj.onc.1202758
– year: 2007
  ident: 5
– volume: 2
  start-page: 91
  issue: 2
  year: 2002
  ident: 51
  publication-title: Nature Reviews Cancer
  doi: 10.1038/nrc727
– ident: 145
  doi: 10.1081/CNV-200050453
– ident: 161
  doi: 10.1038/35025220
– volume: 54
  start-page: 236
  issue: 2
  year: 1995
  ident: 192
  publication-title: Journal of Neuropathology and Experimental Neurology
  doi: 10.1097/00005072-199503000-00010
– ident: 2
  doi: 10.1101/gad.1596707
– ident: 110
  doi: 10.1074/jbc.R000028200
– ident: 224
  doi: 10.1083/jcb.200105109
– ident: 135
  doi: 10.1242/jcs.01631
– volume: 2
  start-page: 306
  issue: 4
  year: 2000
  ident: 151
  publication-title: Neoplasia
  doi: 10.1038/sj.neo.7900102
– volume: 1
  start-page: 44
  issue: 1
  year: 1999
  ident: 14
  publication-title: Neuro-Oncology
  doi: 10.1093/neuonc/1.1.44
– ident: 128
  doi: 10.1016/S0960-9822(99)80286-3
– ident: 164
  doi: 10.1517/13543784.17.8.1225
– ident: 221
  doi: 10.1042/0264-6021:3460561
– volume: 153
  start-page: 569
  issue: 3
  year: 2001
  ident: 108
  publication-title: The Journal of Cell Biology
  doi: 10.1083/jcb.153.3.569
– volume: 57
  start-page: 4183
  issue: 19
  year: 1997
  ident: 20
  publication-title: Cancer Research
– volume: 55
  start-page: 2752
  issue: 13
  year: 1995
  ident: 78
  publication-title: Cancer Research
– ident: 60
  doi: 10.1242/jcs.00792
– ident: 230
  doi: 10.1158/1535-7163.MCT-08-0629
– ident: 126
  doi: 10.1126/science.1092053
– ident: 118
  doi: 10.1083/jcb.200206043
– ident: 186
  doi: 10.1073/pnas.171076798
– ident: 239
  doi: 10.1186/1471-2202-9-S2-S4
– volume: 372
  start-page: 786
  issue: 6508
  year: 1994
  ident: 105
  publication-title: Nature
  doi: 10.1038/372786a0
– ident: 47
  doi: 10.1146/annurev.cellbio.12.1.463
– volume: 97
  start-page: 221
  issue: 2
  year: 1999
  ident: 116
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80732-1
– ident: 187
  doi: 10.1371/journal.pmed.0050008
– ident: 206
  doi: 10.1002/cm.20053
– volume: 2
  start-page: 442
  issue: 6
  year: 2002
  ident: 215
  publication-title: Nature reviews Cancer
  doi: 10.1038/nrc822
– ident: 203
  doi: 10.2174/156800906776842948
– ident: 114
  doi: 10.1002/cm.20030
– ident: 91
  doi: 10.1007/s11060-008-9656-8
– volume: 108
  start-page: 224
  issue: 3
  year: 2004
  ident: 89
  publication-title: Acta Neuropathologica
– volume: 38
  start-page: 755
  issue: 4
  year: 1996
  ident: 43
  publication-title: Neurosurgery
  doi: 10.1227/00006123-199604000-00026
– volume: 22
  start-page: 1715
  issue: 10
  year: 2001
  ident: 31
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/22.10.1715
– ident: 32
  doi: 10.1002/pbc.20803
– volume: 60
  start-page: 1383
  issue: 5
  year: 2000
  ident: 15
  publication-title: Cancer Research
– volume: 61
  start-page: 6624
  issue: 18
  year: 2001
  ident: 149
  publication-title: Cancer Research
– ident: 180
  doi: 10.1158/1535-7163.MCT-08-0669
SSID ssj0064096
Score 2.1427035
Snippet Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the...
SourceID pubmedcentral
proquest
crossref
pubmed
hindawi
emarefa
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 1
SubjectTerms Review
SummonAdditionalLinks – databaseName: Hindawi Publishing Open Access
  dbid: RHX
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1bS8MwFA46mPgi3qb1RsC9lq3Npc2DDyLOIdQH2WBvJWkyV3CtuA7x33vSdtNNGb4VekLDd5Kc7-RcilB7TIVm1JafEUlcqiR3lQYiF2olFNcGGLItcI6eeH9IH0dsVCfIzn6H8MHadWy8tkMt9YejdjsMbOLWc3-0OG85eChlDRGH7RJS1q2r8NaGrtidpplKeABj1JxY1_cj_YtgrudJ_jA8vX20VzNGfFup-ABtmewQ7UR1TPwI3US2gCiZfE5BKkpfKpViOcMSD76rq_CgzPnGaYYfXtNcAWsu8qk8RsPe_eCu79Y_RXATRlgBcHqSCkDRC7Xh9jZC-DwZd7mvSVf5wRgIHbgQwghmJOFUCQ3zB79o7GsdJB5poUaWZ-YU4dAjYJ-DRBANTlHiS6OYBDqoBGcq8IyD2gvI4req90Vc-gyMxRbZuELWQa0azqUUWDwgMg66rtHdPBwvkI9hadt4hcxMPp_FAaGWIRKxQQQIILhErOugk0pXy0_5QK58oHcOCla0uBSwjbVX32TppGyw7QvbxcY7-9f8z9FulVFgr2UuUKN4n5tLICqFuirX6Rf1m990
  priority: 102
  providerName: Hindawi Publishing
– databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1LSwMxEB6KongRX9X1RcBea7t5bXMoIqKIUE8WeluSTdoutFvtA-2_d9LdllZEbws7YcM3yc73ZTIJQKXLlRXcl58xzarcaFk1FolcwxplpHXIkH2Bc-tVPrf5S0d0SrC8jLMAcPKrtPP3SbXHg9uvj_kdTvjmYsILUfMJ3Rr32gD_xdsUQ6Lf29Xiq3SCRBEji-K8Hw02wtGOG2p8wBi10_eK-DP9jXf-3D65Fo-eDmC_IJLkPvf8IZRcdgS7rSJVfgzNlq8rSvrzIVoN017uaaInRJO1oiuSbwUnaUZ6g3RkkExPR0N9Au2nx7eH52pxV0I1EUxMEeVQc4Xghg3rpF-kUFQm3bqkltUNjbrI81BZKKeE00xyoyz2H-VSl1obJSErw1Y2ytwZkEbIMGxHiWIWtVJCtTNCI0s0SgoThS6AyhKy-D0_EiNeSAkhYo9snCMbQLmAc2WFgRD5TQA3Bbp_NydL5GMc8T6NoTM3mk3iiHFPHJn6wwR5ISolUQ_gNPfV6lMUORdF1hdAtOHFlYE_b3vzTZb2F-duU-UPtwnP_-_ZBezluwz8Us0lbE3HM3eF5GVqrhcD8xtR1-wo
  priority: 102
  providerName: Scholars Portal
Title Mesenchymal Migration as a Therapeutic Target in Glioblastoma
URI https://search.emarefa.net/detail/BIM-471635
https://dx.doi.org/10.1155/2010/430142
https://www.ncbi.nlm.nih.gov/pubmed/20652056
https://search.proquest.com/docview/734008339
https://search.proquest.com/docview/754559750
https://pubmed.ncbi.nlm.nih.gov/PMC2905941
Volume 2010
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dS-NAEB_aQuVexDv1jN7Jwvla87EfyT74IGItBzmOo0Lfwm52awMmFW0R_3tn89Grh_hwL0sgsyTMTDK_3-7MLMDZnEnDmSs_o4qOmFZipA0CucRoqYWxiJBdgXP6S0xu2c8Zn_WAd7UwddJ-rovz6r48r4pFnVv5UOZ-lyfm_06vIum6jIR-H_oYfjuK3vx-BRKWuqRI4NeTMB60RXkYN3238-szRyLcITYRRt8ocCdXb0WkoS0VXmCYGi4cKX4u3oOe_2ZQboWk8R7stliSXDbv_Bl6tvoCO2m7W74PF6krLcoXLyVKpcVdY2yinogi0791V2RaZ4OToiI398VSI55eLUt1ALfj6-nVZNQelzDKOeUrVHSomET9homxwq1TyEjk80BEhgY6iucI9ZBcSCu5VVQwLQ2-PzKmeWRMnIf0EAbVsrJHQJKQYuSOc0kN0qU8UlZzhUBRS8F1HFoPzjqVZQ9NV4ysZhOcZ07JWaNkDw5bdW6kMBYixPHgR6vdj6eTTvMZOr3byVCVXa6fspgyhx2p_EAEoSGSJR548LWx1eZRneE9iN9YcSPgWm6_vYOeWLfebj3v-L9nnsCnJv_ALeJ8g8HqcW2_I6xZ6VPo38xCHFOW4PhnMjutHfsVRgL2Bg
link.rule.ids 230,314,727,780,784,863,878,885,2221,24318,27924,27925,53791,53793
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwEB5BVwUuaHd5hX1ZWq4lDz9SHzis0Ha7QCoOReIW2bFLI5EUQSvEv2ecR6FoxWFvkWIr1jeTzPfFM2OAowmThjNXfkYV7TGtRE8bJHJ9o6UWxiJDdgXOyUgMr9jZNb9eA97WwlRJ-5nOj8vb4rjMp1Vu5V2R-W2emH-ZnEbSdRkJ_XX4wGksw1ak1x9ggZKlKioS-P70GQ-asjyMnL7b-_WZkxHuGJsI428UuLOrX8Wkri0UXmCg6k6dLH7M_0U-3-ZQvgpKg4-w3bBJ8qte9SdYs-Vn2Eia_fIdOElccVE2fSpwVJLf1OYm6oEoMn6pvCLjKh-c5CX5c5vPNDLq-axQu3A1-D0-HfaaAxN6Gad8jlCHiklEOOwbK9yfChmJbBKIyNBAR_EEyR7KC2klt4oKpqXB9aNmmkTGxFlI96BTzkp7AKQfUozdcSapQcGURcpqrpAqaim4jkPrwVELWXpX98VIKz3BeepATmuQPdhr4FyOwmiIJMeDnw26708nLfIpur3by1ClnS0e0pgyxx6pfGcIkkOUSzzwYL-21fJRreE9iFesuBzgmm6v3kFfrJpvN753-N8zf8DmcJxcpBd_R-dfYKvORnC_dL5CZ36_sN-Q5Mz198qlnwEN4fZ9
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9tAEB5RKhCXivJ0S8tKcA1-7MPZQw9VIA0tRhyCxM3a9a6JJexEEIT49531IwRUcejNkmfl1czY833eeQAc50wazlz5GVW0x7QSPW0QyPWNlloYiwjZFTgnl2J0zX7f8JulUV910n6mi5PqrjypikmdWzkrM7_LE_OvkkEkXZeR0J-Z3P8AHzlFJ-uIevMRFkhb6sIige9Qn_GgLc3D6Om781-fOSrhRtlEGIOjwM2vXopLa7ZUeIHBam3iqPFT8S8A-jaPcikwDTfhU4soyc9m559hxVZbsJ60Z-bb8CNxBUbZ5LlEqaS4bUxO1ANRZPxSfUXGdU44KSry666YakTV82mpduB6eDYejHrt0IReximfo7pDxSRqOewbK9zfChmJLA9EZGigozhHwIcUQ1rJraKCaWlw_8ib8siYOAvpLqxW08ruA-mHFON3nElqkDRlkbKaK4SLWgqu49B6cNypLJ01vTHSmlNwnjolp42SPdht1bmQwoiIQMeDo1a77y8nneZTdH13nqEqO318SGPKHIKk8h0RBIhImXjgwV5jq8WjOsN7EL-y4kLANd5-fQf9sW7A3frfl_9eeQjrV6fD9OL88s9X2GgSEtxfnQNYnd8_2m-Ic-b6e-3RfwGxj_eQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Mesenchymal+migration+as+a+therapeutic+target+in+glioblastoma&rft.jtitle=Journal+of+oncology&rft.au=Zhong%2C+Jessie&rft.au=Paul%2C+Andre&rft.au=Kellie%2C+Stewart+J&rft.au=O%27Neill%2C+Geraldine+M&rft.date=2010-01-01&rft.eissn=1687-8450&rft.volume=2010&rft.spage=430142&rft.epage=430142&rft_id=info:doi/10.1155%2F2010%2F430142&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1687-8450&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1687-8450&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1687-8450&client=summon