Evaluation on the persistence of anti-HPV immune responses to the quadrivalent HPV vaccine in Chinese females and males: Up to 3.5 years of follow-up

• Published in: Vaccine Vol. 36; no. 11; pp. 1368 - 1374
• Main Authors: Huang, Teng, Liu, Youping, Li, Yanping, Liao, Yuqin, Shou, Qiong, Zheng, Minghuan, Liao, Xueyan, Li, Rongcheng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 07.03.2018; Elsevier Limited
• Subjects: Adolescent; Adult; Allergy and Immunology; Alphapapillomavirus - classification; Alphapapillomavirus - immunology; Antibodies; Antibodies, Viral - blood; Antibodies, Viral - immunology; Approximation; Cervical cancer; Child; China - epidemiology; Dosage; Female; Females; Follow-Up Studies; Human papillomavirus; Human papillomavirus (HPV); Humans; Immune response; Immunoassay; immunoassays; Immunogenicity; Immunogenicity, Vaccine; Immunoglobulin G; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunoglobulins; Laboratories; Long-term follow-up; Male; Males; Middle Aged; Papillomaviridae; Papillomavirus Infections - epidemiology; Papillomavirus Infections - immunology; Papillomavirus Infections - prevention & control; Papillomavirus Vaccines - administration & dosage; Papillomavirus Vaccines - adverse effects; Papillomavirus Vaccines - immunology; Quadrivalent vaccine; Seroepidemiologic Studies; Serogroup; seroprevalence; Vaccination; Vaccines; Womens health; Young Adult; China; Long-term follow-up; Human papillomavirus (HPV); Immunogenicity; Quadrivalent vaccine
• ISSN: 0264-410X; 1873-2518; 1873-2518
• DOI: 10.1016/j.vaccine.2018.02.006

•The immune responses to qHPV vaccine in Chinese subjects at month 42 following vaccination were investigated.•Two immunoassays were used, cLIA and IgG LIA.•The results of this study were similar to those observed in the global studies. The seropositivity of anti-HPV 6, 11, 16 remained high with bot...