T2 relaxation time alterations underlying neurocognitive deficits in alcohol-use disorders (AUD) in an Indian population: A combined conventional ROI and voxel-based relaxometry analysis

• Published in: Alcohol (Fayetteville, N.Y.) Vol. 49; no. 7; pp. 639 - 646
• Main Authors: Bagga, Deepika, Modi, Shilpi, Poonia, Mahesh, Kaur, Prabhjot, Bhattacharya, D., Garg, M.L., Khushu, Subash, Singh, Namita
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2015; Elsevier Limited
• Subjects: Adult; Age; Alcohol; Alcohol-Related Disorders - pathology; Alcohol-Related Disorders - psychology; Alcoholism; Alcoholism - pathology; Alcoholism - psychology; Brain; Brain - pathology; Brain Mapping; Cognition Disorders - pathology; Cognition Disorders - psychology; Cognitive ability; Cognitive deficits; Demyelinating Diseases - pathology; Demyelinating Diseases - psychology; Female; Gliosis - pathology; Gliosis - psychology; Humans; Image Processing, Computer-Assisted; India; Intelligence Tests; Magnetic Resonance Imaging; Male; Memory; Memory - physiology; Mental disorders; Metabolism; Middle Aged; Neuropsychological Tests; NMR; Nuclear magnetic resonance; Psychiatry; Studies; T2 relaxation time; Voxel-based relaxometry; Young Adult; India; Voxel-based relaxometry; Brain; T2 relaxation time; Cognitive deficits; Alcoholism

Long-term heavy alcohol consumption has traditionally been associated with impaired cognitive abilities, such as deficits in abstract reasoning, problem solving, verbal fluency, memory, attention, and visuospatial processing. The present study aimed at exploring these neuropsychological deficits in...