Humoral and cellular immune memory response 12 years following single dose vaccination against hepatitis A in Argentinian children

• Published in: Vaccine Vol. 40; no. 1; pp. 114 - 121
• Main Authors: Urueña, A., Badano, M.N., Baré, P., González, J., Vicentín, R., Calli, R., Cañero-Velasco, M.C., Fink, S., Vizzotti, C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 03.01.2022; Elsevier Limited
• Subjects: Allergy and Immunology; Antibodies; Antigens; Argentina; CD4 antigen; CD4-positive T-lymphocytes; CD8 antigen; CD8-positive T-lymphocytes; Cytokines; Epidemics; Flow cytometry; Hepatitis; Hepatitis A; Hepatitis A - prevention & control; Hepatitis A Antibodies; Hepatitis A Vaccines; Hepatitis A Virus; Hepatovirus A; Hospitals; Humans; Immunity; Immunologic Memory; Immunological memory; Immunology; Infections; Leukocytes, Mononuclear; Lymphocytes; Lymphocytes T; memory; Memory cells; Memory Response; Memory T Cells; Pediatrics; Peripheral blood; Public health; Vaccination; Vaccines; Viral infections; United States > US; Argentina; Immunity; Memory Response; Vaccination; Hepatitis A Virus

•HAV booster vaccination elicited an adequate humoral memory response in most individuals.•HAV-specific memory T-cells response was observed independently of anti-HAV antibodies titers.•Long-term humoral and cellular immunity demonstrated here, supports the single-dose HAV strategy. Infants’ univers...