Multiparametric autoantibody analysis: a new paradigm for the diagnosis of connective tissue diseases

• Published in: Arthritis research & therapy Vol. 24; no. 1; pp. 278 - 10
• Main Authors: Bizzaro, Nicola, Villalta, Danilo, Bini, Vittorio, Migliorini, Paola, Franceschini, Franco, Piantoni, Silvia, Garrafa, Emirena, Riccieri, Valeria, Fioravanti, Antonella, Bellisai, Francesca, Tampoia, Marilina, Fornaro, Marco, Iannone, Florenzo, Ghirardello, Anna, Zen, Margherita, Palterer, Boaz, Parronchi, Paola, Infantino, Maria, Benucci, Maurizio, Rigon, Amelia, Arcarese, Luisa, Del Rosso, Stefania, Canti, Valentina, Bartoloni, Elena, Gerli, Roberto, Bistoni, Onelia, Cafaro, Giacomo, Perricone, Carlo, Topini, Fabiana, Cavazzana, Ilaria, Fredi, Micaela, Masneri, Stefania, Cheleschi, Sara, Bacarelli, Maria-Romana, Cammelli, Daniele, Manfredi, Mariangela, Giacomelli, Roberto, Querini, Patrizia Rovere
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.12.2022; BioMed Central; BMC
• Subjects: Analysis; Autoantibodies; Autoantibody profiling; Connective tissue diseases; Connective Tissue Diseases - diagnosis; Development and progression; Diagnosis; Health aspects; Humans; Identification and classification; Lupus Erythematosus, Systemic; Multiplex testing; Particle-based multi-analyte technology; Rheumatic Diseases - diagnosis; Risk factors; Sjogren's Syndrome - diagnosis; Italy; Autoantibody profiling; Connective tissue diseases; Particle-based multi-analyte technology; Multiplex testing

In patients affected by connective tissue diseases (CTDs), the identification of wide autoantibody profiles may prove useful in early diagnosis, in the evaluation of prognosis (risk stratification), and in predicting response to therapy. The aim of the present study was to evaluate the utility of mu...