Pulsed Field Ablation for the Treatment of Atrial Fibrillation: PULSED AF Pivotal Trial

• Published in: Circulation (New York, N.Y.) Vol. 147; no. 19; pp. 1422 - 1432
• Main Authors: Verma, Atul, Haines, David E., Boersma, Lucas V., Sood, Nitesh, Natale, Andrea, Marchlinski, Francis E., Calkins, Hugh, Sanders, Prashanthan, Packer, Douglas L., Kuck, Karl-Heinz, Hindricks, Gerhard, Onal, Birce, Cerkvenik, Jeffrey, Tada, Hiroshi, DeLurgio, David B.
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 09.05.2023
• Subjects: Anti-Arrhythmia Agents - therapeutic use; Atrial Fibrillation - drug therapy; Atrial Fibrillation - surgery; Catheter Ablation - adverse effects; Catheter Ablation - methods; Electrocardiography; Humans; Original s; Prospective Studies; Pulmonary Veins; Recurrence; Treatment Outcome; clinical trial; atrial fibrillation; catheter ablation; electroporation; pulsed field ablation

Pulsed field ablation uses electrical pulses to cause nonthermal irreversible electroporation and induce cardiac cell death. Pulsed field ablation may have effectiveness comparable to traditional catheter ablation while preventing thermally mediated complications. The PULSED AF pivotal study (Pulsed...