The anti-cancer properties of heparin and its derivatives: a review and prospect

• Published in: Cell adhesion & migration Vol. 14; no. 1; pp. 118 - 128
• Main Authors: Ma, Sai-Nan, Mao, Zhi-Xiang, Wu, Yang, Liang, Ming-Xing, Wang, Dan-Dan, Chen, Xiu, Chang, Ping-an, Zhang, Wei, Tang, Jin-Hai
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2020; Taylor & Francis Group
• Subjects: cancer; Heparin; heparin derivatives; low-molecular-weight heparin; metastasis; Review; cancer; low-molecular-weight heparin; Heparin; metastasis; heparin derivatives

Heparin, including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH) and heparin derivatives, are commonly used in venous thromboembolism treatment and reportedly have beneficial effects on cancer survival. Heparin can affect the proliferation, adhesion, angiogenesis, migration and i...