Efficacy of a combination of praziquantel and artesunate in the treatment of urinary schistosomiasis in Nigeria

• Published in: Transactions of the Royal Society of Tropical Medicine and Hygiene Vol. 103; no. 1; pp. 38 - 44
• Main Authors: Inyang-Etoh, P.C., Ejezie, G.C., Useh, M.F., Inyang-Etoh, E.C.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.01.2009; Royal Society of Tropical Medicine and Hygiene; Oxford University Press
• Subjects: Administration, Oral; Adolescent; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiparasitic agents; Antiparasitic Agents - therapeutic use; Artemisinins - therapeutic use; Artesunate; Biological and medical sciences; Child; Child, Preschool; Combination drug therapy; Diseases caused by trematodes; Drug Therapy, Combination; Endemic Diseases; Female; General aspects; Helminthic diseases; Humans; Infectious diseases; Male; Medical sciences; Nigeria; Nigeria - epidemiology; Parasite Egg Count; Parasitic diseases; Pharmacology. Drug treatments; Praziquantel; Praziquantel - therapeutic use; Schistosoma haematobium - isolation & purification; Schistosomiases; Schistosomiasis haematobia - drug therapy; Schistosomiasis haematobia - epidemiology; Schistosomiasis haematobia - urine; Treatment Outcome; Urinary schistosomiasis; Young Adult; Nigeria; Africa; Treatment outcome; Urinary schistosomiasis; Nigeria; Praziquantel; Artesunate; Combination drug therapy; Antimalarial; Drug combination; Anthelmintic; Prognosis; Trematode disease; Parasitosis; Helminthiasis; Infection; Schistosomiasis; Parasiticide; Tropical medicine; Combined treatment

The combined effects of praziquantel and artesunate in the treatment of urinary schistosomiasis were assessed among 312 randomly selected schoolchildren aged 4–20 years in Adim community, Nigeria. In the preliminary screening, infection was confirmed in 327 (38.5%) of the 850 subjects screened. Infe...