Genomic characterization of carbapenem-non-susceptible Pseudomonas aeruginosa in Singapore

• Published in: Emerging microbes & infections Vol. 10; no. 1; pp. 1706 - 1716
• Main Authors: Teo, Jocelyn Qi-Min, Tang, Cheng Yee, Lim, Jie Chong, Lee, Shannon Jing-Yi, Tan, Si Hui, Koh, Tse-Hsien, Sim, James Heng-Chiak, Tan, Thuan-Tong, Kwa, Andrea Lay-Hoon, Ong, Rick Twee-Hee
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2021; Taylor & Francis Group
• Subjects: Anti-Bacterial Agents - pharmacology; Bacterial Typing Techniques; Carbapenems - pharmacology; clones; Drug Resistance, Bacterial; Genome, Bacterial; genomic surveillance; Genomics - methods; Humans; Microbial Sensitivity Tests; multi-drug resistant; Multilocus Sequence Typing; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas aeruginosa - classification; Pseudomonas aeruginosa - drug effects; Pseudomonas aeruginosa - genetics; resistome; Singapore; Whole Genome Sequencing; Singapore; Pseudomonas aeruginosa; resistome; multi-drug resistant; clones; whole-genome sequencing; genomic surveillance

Pseudomonas aeruginosa is a clinically important pathogen implicated in many hospital-acquired infections. Its propensity to acquire broad-spectrum resistance has earned the organism its status as a severe public health threat requiring urgent control measures. While whole-genome sequencing-based ge...