Prediction of motion artifacts caused by translation in handheld laser speckle contrast imaging

• Published in: Journal of biomedical optics Vol. 28; no. 4; p. 046005
• Main Authors: Chizari, Ata, Tsong, Wilson, Knop, Tom, Steenbergen, Wiendelt
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.04.2023; SPIE; S P I E - International Society for
• Subjects: Computer Simulation; Correlation; Delrin (trademark); Dermatology; Diagnostic Imaging; Doppler effect; Illumination; Imaging; Laser Speckle Contrast Imaging; Laser-Doppler Flowmetry - methods; Lasers; Light; Medical imaging; Physical properties; Predictions; Psoriasis; Regional Blood Flow; Scattering; Simulation; Translation; Ultrasonography, Doppler; laser speckle contrast imaging; motion artifacts; numerical analysis; computer simulation; Doppler effect; analytical models; model-driven development; biomedical optical imaging

In handheld laser speckle contrast imaging (LSCI), motion artifacts (MA) are inevitable. Suppression of MA leads to a valid and objective assessment of tissue perfusion in a wide range of medical applications including dermatology and burns. Our study shines light on the sources of these artifacts,...