Rapid detection assay of toxigenic Clostridioides difficile through PathOC RightGene, a novel high-speed polymerase chain reaction device

• Published in: Diagnostic Microbiology and Infectious Disease Vol. 99; no. 2; p. 115247
• Main Authors: Okanda, Takashi, Mitsutake, Hiroshi, Aso, Ryoko, Sekizawa, Ryuichi, Takemura, Hiromu, Matsumoto, Tetsuya, Nakamura, Shigeki
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2021; Elsevier BV
• Subjects: Bacterial Toxins; Binary toxin; Clostridioides difficile; Clostridioides difficile infection; Clostridium; Clostridium Infections; Feces; High-speed polymerase chain reaction; Humans; Immunoenzyme Techniques; Molecular Diagnostic Techniques; Nucleic acid amplification tests; Point-of-Care Testing; Polymerase Chain Reaction; Sensitivity and Specificity; Toxin B; Point-of-care testing; Clostridioides difficile infection; Binary toxin; Toxin B; High-speed polymerase chain reaction; Nucleic acid amplification tests

Nucleic acid amplification tests for diagnosing Clostridioides difficile infections (CDI) are improving to become faster and more accurate. This study aimed to evaluate the accuracy of rapid detection of toxigenic C. difficile using the novel high-speed polymerase chain reaction (PCR) device, PathOC...