The promise of endogenous and exogenous riboflavin in anti-infection

• Published in: Virulence Vol. 12; no. 1; pp. 2314 - 2326
• Main Authors: Lei, Junwen, Xin, Caiyan, Xiao, Wei, Chen, Wenbi, Song, Zhangyong
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2021; Taylor & Francis Group
• Subjects: Anti-Infective Agents; Antibacterial agent; antifungal agent fmn riboswitch; Cytokines - immunology; Heat-Shock Proteins - immunology; immune response; mait cell; Review; Reviews; riboflavin; Riboflavin - metabolism; Riboflavin - pharmacology; antifungal agent fmn riboswitch; mait cell; Antibacterial agent; immune response; riboflavin

To resolve the growing problem of drug resistance in the treatment of bacterial and fungal pathogens, specific cellular targets and pathways can be used as targets for new antimicrobial agents. Endogenous riboflavin biosynthesis is a conserved pathway that exists in most bacteria and fungi. In this...