Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis - Wu, Jianfeng; Huang, Zhe; Ren, Junming; Zhang, Zhirong; He, Peng; Li, Yangxin; Ma, Jianhui; Chen, Wanze; Zhang, Yingying; Zhou, Xiaojuan; Yang, Zhentao; Wu, Su-Qin; et al. (Cell research, 2013)
Keywords: 631/45/127/1220; 631/80/82/2344; 631/80/86; Amino Acid Chloromethyl Ketones - pharmacology; Animals; Apoptosis; Base Sequence; Biomedical and Life Sciences; Cell Biology; Cell Line; Interleukin-1beta - metabolism; Interleukin-6 - metabolism; Life Sciences; Lipopolysaccharides - toxicity; Macrophages - drug effects; Macrophages - metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria - drug effects; Mitochondria - metabolism; Mitogen-Activated Protein Kinase Kinases - metabolism; Necrosis; NF-kappa B - metabolism; NF-κB; Original; original-article; Protein Kinases - deficiency; Protein Kinases - genetics; Protein Kinases - metabolism; Receptor-Interacting Protein Serine-Threonine Kinases - deficiency; Receptor-Interacting Protein Serine-Threonine Kinases - genetics; Receptor-Interacting Protein Serine-Threonine Kinases - metabolism; Signal Transduction - drug effects; Tumor Necrosis Factor-alpha - pharmacology; Tumor Necrosis Factors - metabolism; 坏死性; 基因敲除; 小鼠; 巨噬细胞; 白细胞介素; 肿瘤坏死因子; 胚胎成纤维细胞; apoptosis; Mlkl; Rip3; TNF; mice; necroptosis