Acceptance of a COVID-19 vaccine and associated factors among pregnant women in China: a multi-center cross-sectional study based on health belief model
Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases. Methods: A multi-center cross-sectional study among pregnan...
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Published in | Human vaccines & immunotherapeutics Vol. 17; no. 8; pp. 2378 - 2388 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Taylor & Francis
03.08.2021
Taylor & Francis Group |
Subjects | |
Online Access | Get full text |
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Abstract | Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases.
Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance.
Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80).
Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. |
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AbstractList | : Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases.
A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance.
Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80).
About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. Background : Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases. Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance. Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1–79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20–2.93), western region (aOR = 2.73, 95% CI: 1.72–4.32), low level of education (aOR = 2.49, 95% CI: 1.13–5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03–2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01–1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36–3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23–10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36–3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28–29.80). Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases. Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance. Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80). Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases. Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance. Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1–79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20–2.93), western region (aOR = 2.73, 95% CI: 1.72–4.32), low level of education (aOR = 2.49, 95% CI: 1.13–5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03–2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01–1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36–3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23–10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36–3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28–29.80). Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases.Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance.Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80).Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations.Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases.Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance.Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80).Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. |
Author | Sun, Fenglan Deng, Lixia Liu, Jue Han, Na Yuan, Chuanxiang Wang, Ruitong Tao, Liyuan Liu, Min Liu, Jihong Han, Chunhua |
Author_xml | – sequence: 1 givenname: Liyuan orcidid: 0000-0003-3497-1326 surname: Tao fullname: Tao, Liyuan organization: Peking University Third Hospital – sequence: 2 givenname: Ruitong surname: Wang fullname: Wang, Ruitong organization: Peking University – sequence: 3 givenname: Na surname: Han fullname: Han, Na organization: Tongzhou Maternal and Child Health Hospital – sequence: 4 givenname: Jihong surname: Liu fullname: Liu, Jihong organization: The Second Affiliated Hospital of Kunming Medical University – sequence: 5 givenname: Chuanxiang surname: Yuan fullname: Yuan, Chuanxiang organization: Qianjiang Maternal and Child Health Hospital – sequence: 6 givenname: Lixia surname: Deng fullname: Deng, Lixia organization: Qianjiang Central Hospital – sequence: 7 givenname: Chunhua surname: Han fullname: Han, Chunhua organization: Qujing Maternal and Child Health Hospital – sequence: 8 givenname: Fenglan surname: Sun fullname: Sun, Fenglan organization: Shexian Maternal and Child Health Hospital – sequence: 9 givenname: Min surname: Liu fullname: Liu, Min organization: Peking University – sequence: 10 givenname: Jue orcidid: 0000-0002-1938-9365 surname: Liu fullname: Liu, Jue email: jueliu@bjmu.edu.cn organization: Peking University Health Science Center |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33989109$$D View this record in MEDLINE/PubMed |
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References_xml | – ident: e_1_3_4_2_1 – ident: e_1_3_4_21_1 doi: 10.1111/phn.12600 – ident: e_1_3_4_8_1 doi: 10.1016/j.amepre.2015.06.009 – ident: e_1_3_4_28_1 doi: 10.1080/07370016.2011.539087 – ident: e_1_3_4_5_1 doi: 10.1016/j.cell.2020.09.040 – volume: 147 start-page: w14526 year: 2017 ident: e_1_3_4_19_1 article-title: Review of maternal immunisation during pregnancy: focus on pertussis and influenza publication-title: Swiss Med Wkly – volume: 2214 start-page: 30484 issue: 20 year: 2020 ident: e_1_3_4_48_1 article-title: Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to action publication-title: Lancet Glob Health – ident: e_1_3_4_13_1 doi: 10.1016/S1473-3099(20)30426-6 – ident: e_1_3_4_36_1 doi: 10.1016/j.vaccine.2018.10.049 – ident: e_1_3_4_33_1 doi: 10.15585/mmwr.mm6638a2 – ident: e_1_3_4_49_1 doi: 10.1016/j.vaccine.2020.12.074 – ident: e_1_3_4_25_1 doi: 10.3390/ijerph14121551 – ident: e_1_3_4_41_1 doi: 10.1016/j.vaccine.2014.01.081 – ident: e_1_3_4_24_1 – ident: e_1_3_4_22_1 doi: 10.1016/j.vaccine.2020.08.015 – ident: e_1_3_4_45_1 doi: 10.1080/07370016.2011.539087 – ident: e_1_3_4_26_1 doi: 10.1016/j.vaccine.2016.01.056 – ident: e_1_3_4_31_1 doi: 10.1093/cid/ciy737 – ident: e_1_3_4_4_1 doi: 10.1016/S2468-2667(16)30001-9 – ident: e_1_3_4_11_1 doi: 10.3390/vaccines8040582 – ident: e_1_3_4_20_1 doi: 10.1080/21645515.2015.1027470 – ident: e_1_3_4_34_1 doi: 10.1080/21645515.2018.1483809 – ident: e_1_3_4_35_1 doi: 10.1016/j.vaccine.2015.08.093 – ident: e_1_3_4_46_1 – ident: e_1_3_4_38_1 doi: 10.1371/journal.pone.0215978 – ident: e_1_3_4_27_1 doi: 10.1177/109019818801500203 – ident: e_1_3_4_7_1 doi: 10.1093/cid/ciaa433 – ident: e_1_3_4_10_1 doi: 10.7326/M20-3569 – ident: e_1_3_4_43_1 doi: 10.1136/bmj.m3320 – ident: e_1_3_4_16_1 doi: 10.1016/j.ebiom.2016.08.042 – ident: e_1_3_4_17_1 doi: 10.1186/s12889-019-7172-8 – ident: e_1_3_4_29_1 doi: 10.1177/00333549111260S215 – ident: e_1_3_4_12_1 doi: 10.1016/j.vaccine.2020.09.041 – ident: e_1_3_4_6_1 – ident: e_1_3_4_32_1 doi: 10.1016/j.eclinm.2020.100522 – ident: e_1_3_4_42_1 doi: 10.15585/mmwr.mm6938e1 – ident: e_1_3_4_3_1 doi: 10.1016/S0140-6736(20)32318-7 – ident: e_1_3_4_18_1 doi: 10.1080/21645515.2019.1596713 – ident: e_1_3_4_40_1 doi: 10.1016/B978-0-12-802174-3.00026-6 – ident: e_1_3_4_44_1 doi: 10.1016/j.ajogmf.2020.100107 – ident: e_1_3_4_47_1 doi: 10.3760/cma.j.cn112137-20210104-00008 – ident: e_1_3_4_15_1 doi: 10.1016/S0140-6736(10)60421-7 – ident: e_1_3_4_23_1 doi: 10.1016/j.vaccine.2015.09.035 – ident: e_1_3_4_9_1 doi: 10.3390/vaccines8030482 – ident: e_1_3_4_37_1 doi: 10.3390/ijerph111212162 – ident: e_1_3_4_39_1 doi: 10.1017/S0950268816002491 – start-page: 225 ident: e_1_3_4_14_1 article-title: A global survey of potential acceptance of a COVID-19 vaccine publication-title: Nat Med – ident: e_1_3_4_30_1 |
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Snippet | Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related... : Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among... Background : Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related... |
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SubjectTerms | acceptance China COVID-19 COVID-19 Vaccines Cross-Sectional Studies Female Health Belief Model Humans Pandemics Pregnancy Pregnant Women Research Paper SARS-CoV-2 Vaccination vaccine vaccine hesitancy Vaccines |
Title | Acceptance of a COVID-19 vaccine and associated factors among pregnant women in China: a multi-center cross-sectional study based on health belief model |
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