A novel cascade machine learning pipeline for Alzheimer's disease identification and prediction

• Published in: Frontiers in aging neuroscience Vol. 14; p. 1073909
• Main Authors: Zhou, Kun, Piao, Sirong, Liu, Xiao, Luo, Xiao, Chen, Hongyi, Xiang, Rui, Geng, Daoying
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 16.01.2023
• Subjects: Aging Neuroscience; Alzheimer’s disease; automatic segmentation; coronal T1 weighted images; machine learning; radiomics classification; Alzheimer’s disease; automatic segmentation; machine learning; radiomics classification; coronal T1 weighted images

Alzheimer's disease (AD) is a progressive and irreversible brain degenerative disorder early. Among all diagnostic strategies, hippocampal atrophy is considered a promising diagnostic method. In order to proactively detect patients with early Alzheimer's disease, we built an Alzheimer'...