Depletion of circ_0007841 inhibits multiple myeloma development and BTZ resistance via miR-129-5p/JAG1 axis

• Published in: Cell cycle (Georgetown, Tex.) Vol. 19; no. 23; pp. 3289 - 3302
• Main Authors: Wang, Yan, Lin, Quande, Song, Chunge, Ma, Ruojin, Li, Xiaojie
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2020
• Subjects: chemoresistance; circ_0007841; JAG1; metastasis; miR-129-5p; Multiple myeloma; proliferation; Research Paper; chemoresistance; JAG1; proliferation; metastasis; Multiple myeloma; circ_0007841; miR-129-5p

Circular RNAs (circRNAs) possess important regulatory effects on multiple myeloma (MM) progression. Here, we aimed at exploring the function of circ_0007841 in MM and the underlying molecular mechanism. Expression of circ_0007841, microRNA (miR)-129-5p and Jagged1 (JAG1) was determined via qRT-PCR o...